GI Flashcards
Name two types of peptic ulcers:
duodenal ulcers (young 30-55), feel better with feeding
gastric ulcers (old 55-65), feel worse with feeding
signs of symptoms: GNAWING epigastric pain
signs/symptoms of perforated ulcers:
severe epigastric pain
rigid boardlike abd
quiet bowel sounds
What are three causes of a perfed bowel?
peptic ulcer disease
ruptured diverticulum
appendicitis (rare)
This is tested by a urea breath test, can be present with duodenal or gastric ulcers
H. pylori
What is the step-wise approach for outpatient management of peptic ulcer disease?
- 1st line, everybody gets this: H2 blockers*
- -tidine*
- ranitidince (zantac) famotidine (pepcid)*
2nd line: PPIs
-azole
lansoprazole (prevacid) omeprazole (prilosec) esomeprazole (nexmium)
What musosal protective agent is used for traveler’s diarrhea and has direct action against H. pylori?
bismuth subsalicylate (peptobismal)
What mucosal protective agent is used for NSAID induced ulcer prophylaxis and it therefore given to patients with RA who take chronic NSAIDS?
Misopristol (cytotec)
H. pylori eradication therapy includes five possible 3 drug combinations. What three combinations use 2 abx + PPI?
AOC
MOC
MOA
A *amoxicillin+omeprazole+clarithromycin
O *Metronidazole + omeprazole + clarithromycin
M O C *Metronidazole + omeprazole + amoxicillin
O
A
H. pylori eradication therapy includes five possible 3 drug combinations. What are the two regimens that include 2 abx + 1 bismuth?
THE BMT BMTO is not as popular due to qid dosing
BMT: bismuth+metronidazole+tetracycline
BMTO: bismuth+metronidazole+tetracycline+omeprazole
If you suspect a bowel perf, what imaging would you order and what would it show?
upright or decubitus abd xray show in about 75% of cases
you would expect it to show free air under the abd
1) When the normal tissue lining the esophagus changes to tissue that resembles the lining of the intestine.
2) this is a serious complication of GERD.
3) this finding increases the risk of developing esophageal adenocarcinoma, which is a serious, potentially fatal cancer of the esophagus.
Barrett’s esophagus
What are normal platelet count?
150-400
With hepatitis A, the blood and stool are infectious during the _______ week incubation period:
2-6 week incubation period
Hep B is transmitted through:
blood
sexual activity
mother-fetus
Which two types of hepatitis have a vaccine?
A and B
Why do patients in the icteric phase have jaundice?
from unconjugated bilirubin