Geriatrics Flashcards

1
Q

What are microscopic findings in Alzheimer’s Dz?

A

Neurofibrillary tangles

B-amyloid protein plaques

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2
Q

What are three gene’s associated with Alzheimer’s Dz?

A

Amyloid precursor protein gene at Chromosome 21
Presenilin-1 gene at Chromosome 14
Presenilin-2 gene at Chromosome 1

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3
Q

What type of medication is used to treat Alzheimer’s? Name two.

A

Acetylcholinesterase inhibitors

Rivastigmine
Donepezil

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4
Q

What test is commonly done to assess cognitive function? And what do the scores indicate?

A

MMSE

Severe <9
Moderate 10-18
Mild 19-24
Normal > 27

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