GERD/ Heartburn

Question 1

Antacid drugs

Answer 1

• aluminium hydroxide
• magnesium carbonate
• magnesium trisilicate

Question 2

Dosing for Aluminum Hydroxide

Answer 2

PO 5-10ml QDS

Question 3

Side effects of Aluminum Hydroxide

Answer 3

Constipation

Question 4

Counselling points for Aluminum Hydroxide

Answer 4

• taken after meals and bedtime

- do not take with other medications

Question 5

Dosing for magnesium carbonate

Answer 5

PO 10ml TDS

Question 6

Side effects for Magnesium Carbonate

Answer 6

Diarrhoea

Question 7

Contraindication for Magnesium Carbonate

Answer 7

severe renal failure

Question 8

Counselling points for Magnesium Carbonate

Answer 8

• taken after meals and at bedtime

- do not take with other medication

Question 9

Dosing for Magnesium Trisilicate

Answer 9

PO 5-15ml TDS

Question 10

Side effects of Magnesium Trisilicate

Answer 10

diarrhoea

Question 11

Contraindication for Magnesium trisilicate

Answer 11

severe renal failure

Question 12

Counselling points for Magnesium Trisilicate

Answer 12

• taken after meals and at bedtime

- do not take with other medication

Question 13

Alginate Drug

Answer 13

Sodium alginate (gaviscon)

Question 14

Dosing for Gaviscon

Answer 14

PO 10-20ml QDS

Question 15

Side effects for Gaviscon

Answer 15

Diarrhoea

Question 16

Contraindication for Gaviscon

Answer 16

severe renal failure

Question 17

Counselling points for Gaviscon

Answer 17

• taken after meals and before bedtime

- do not take with other medication

Question 18

Antiflatulent Drug

Answer 18

Simethicone

Question 19

Dosing for Simethicone

Answer 19

PO 40-125mg QDS

Question 20

Side effects for Simethicone

Answer 20

NA

Question 21

Contraindication for Simethicone

Answer 21

NA

Question 22

Counselling points Simethicone

Answer 22

Take with or after meals

Question 23

H2 receptor antagonist Drug

Answer 23

Famotidine

Question 24

Famotidine MOA

Answer 24

Competitively blocks H2 receptors on parietal cells reducing acid secretion

Question 25

Proton Pump Inhibitor Drug

Answer 25

omeprazole and esomeprazole

Question 26

PPI MOA

Answer 26

irreversibly inactivate the hydrogen/potassium ATPase proton pump suppressing both stimulated and basal acid secretion

Question 27

Dosing for Omeprazole (GERD)

Answer 27

PO 20mg OD for 4-8 weeks

Question 28

Dosing for Omeprazole (NSAIDs PUD)

Answer 28

PO 20-40mg OD for 4-8 weeks

Question 29

Side effects for Omeprazole

Answer 29

Headache

Question 30

Contraindication for Omeprazole

Answer 30

Hypersensitivity to omeprazole and esomeprazole

Question 31

Counselling points for omeprazole

Answer 31

- administer 30-60 mins before meals | - swallow whole

Question 32

Dosing for Esomeprazole (GERD)

Answer 32

PO 20mg BD for 14 days

Question 33

Dosing for Esomeprazole (NSAIDs PUD)

Answer 33

PO 20mg OD for 4-8 weeks

Question 34

Side effects for Esomeprazole

Answer 34

headache

Question 35

Contraindication for Esomeprazole

Answer 35

Hypersensitivity to omeprazole and esomeprazole

Question 36

Counselling points for Esomeprazole

Answer 36

- administer 30-60 mins before meals | - swallow whole

Question 37

Treatment for gastritis

Answer 37

PPI over 4-8 weeks

Question 38

Treatment for NSAID-induced ulcers

Answer 38

PPI over 4-8 weeks

Question 39

What are the antibiotics in the triple therapy

Answer 39

Amoxicillin Clarithromycin Metronidazole

Question 40

What is Combo 1

Answer 40

Omeprazole 20mg BD Amoxicillin 1g BD Clarithromycin 500mg BD

Question 41

What is Combo 3 for?

Answer 41

Allergic to amoxicillin Omeprazole 20mg BD Clarithromycin 250mg BD Metronidazole 400mg BD

Question 42

How long is triple therapy for?

Answer 42

1 week but can be extended to 2 weeks

Question 43

When is quadruple therapy used?

Answer 43

when there is eradication failure, when patient still has infection despite triple therapy

Question 44

What drugs are in quadruple therapy

Answer 44

PPI Bismuth tetracycline metronidazole