GERD/ Heartburn Flashcards

1
Q

Antacid drugs

A
  • aluminium hydroxide
  • magnesium carbonate
  • magnesium trisilicate
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2
Q

Dosing for Aluminum Hydroxide

A

PO 5-10ml QDS

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3
Q

Side effects of Aluminum Hydroxide

A

Constipation

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4
Q

Counselling points for Aluminum Hydroxide

A
  • taken after meals and bedtime

- do not take with other medications

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5
Q

Dosing for magnesium carbonate

A

PO 10ml TDS

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6
Q

Side effects for Magnesium Carbonate

A

Diarrhoea

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7
Q

Contraindication for Magnesium Carbonate

A

severe renal failure

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8
Q

Counselling points for Magnesium Carbonate

A
  • taken after meals and at bedtime

- do not take with other medication

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9
Q

Dosing for Magnesium Trisilicate

A

PO 5-15ml TDS

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10
Q

Side effects of Magnesium Trisilicate

A

diarrhoea

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11
Q

Contraindication for Magnesium trisilicate

A

severe renal failure

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12
Q

Counselling points for Magnesium Trisilicate

A
  • taken after meals and at bedtime

- do not take with other medication

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13
Q

Alginate Drug

A

Sodium alginate (gaviscon)

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14
Q

Dosing for Gaviscon

A

PO 10-20ml QDS

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15
Q

Side effects for Gaviscon

A

Diarrhoea

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16
Q

Contraindication for Gaviscon

A

severe renal failure

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17
Q

Counselling points for Gaviscon

A
  • taken after meals and before bedtime

- do not take with other medication

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18
Q

Antiflatulent Drug

A

Simethicone

19
Q

Dosing for Simethicone

A

PO 40-125mg QDS

20
Q

Side effects for Simethicone

A

NA

21
Q

Contraindication for Simethicone

A

NA

22
Q

Counselling points Simethicone

A

Take with or after meals

23
Q

H2 receptor antagonist Drug

A

Famotidine

24
Q

Famotidine MOA

A

Competitively blocks H2 receptors on parietal cells reducing acid secretion

25
Q

Proton Pump Inhibitor Drug

A

omeprazole and esomeprazole

26
Q

PPI MOA

A

irreversibly inactivate the hydrogen/potassium ATPase proton pump suppressing both stimulated and basal acid secretion

27
Q

Dosing for Omeprazole (GERD)

A

PO 20mg OD for 4-8 weeks

28
Q

Dosing for Omeprazole (NSAIDs PUD)

A

PO 20-40mg OD for 4-8 weeks

29
Q

Side effects for Omeprazole

A

Headache

30
Q

Contraindication for Omeprazole

A

Hypersensitivity to omeprazole and esomeprazole

31
Q

Counselling points for omeprazole

A
  • administer 30-60 mins before meals

- swallow whole

32
Q

Dosing for Esomeprazole (GERD)

A

PO 20mg BD for 14 days

33
Q

Dosing for Esomeprazole (NSAIDs PUD)

A

PO 20mg OD for 4-8 weeks

34
Q

Side effects for Esomeprazole

A

headache

35
Q

Contraindication for Esomeprazole

A

Hypersensitivity to omeprazole and esomeprazole

36
Q

Counselling points for Esomeprazole

A
  • administer 30-60 mins before meals

- swallow whole

37
Q

Treatment for gastritis

A

PPI over 4-8 weeks

38
Q

Treatment for NSAID-induced ulcers

A

PPI over 4-8 weeks

39
Q

What are the antibiotics in the triple therapy

A

Amoxicillin
Clarithromycin
Metronidazole

40
Q

What is Combo 1

A

Omeprazole 20mg BD
Amoxicillin 1g BD
Clarithromycin 500mg BD

41
Q

What is Combo 3 for?

A

Allergic to amoxicillin
Omeprazole 20mg BD
Clarithromycin 250mg BD
Metronidazole 400mg BD

42
Q

How long is triple therapy for?

A

1 week but can be extended to 2 weeks

43
Q

When is quadruple therapy used?

A

when there is eradication failure, when patient still has infection despite triple therapy

44
Q

What drugs are in quadruple therapy

A

PPI
Bismuth
tetracycline
metronidazole