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PPP > Antiemetic Drug (motion sickness) > Flashcards

Antiemetic Drug (motion sickness) Flashcards

1
Q

dopamine receptor antagonist Drugs

A

Domperidone
Metoclopramide
Prochlorperazine maleate

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2
Q

MOA of dopamine receptor antagonist

A

blocks dopamine receptors enhancing motility in upper GI tract and accelerates gastric emptying

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3
Q

side effects of domperidone

A

dry mouth, migriane, headache

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4
Q

counselling points for domperidone

A

take 15-30min before food

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5
Q

dosing for metoclopramide

A

PO 10mg TDS mx 30mg/day

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6
Q

side effects of metoclopramide

A

drowsiness

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7
Q

counselling points for metoclopramide

A
  • take 30mins before food

- may cause drowsiness, do not drive or operate machinery

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8
Q

Dosing for prochlorperazine maleate

A

PO 5-10mg TDS-QDS

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9
Q

Side effects of prochlorperazine maleate

A

constipation, dry mouth, drowsiness

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10
Q

counselling points for prochlorperazine maleate

A
  • medication can cause drowsiness. Do not drive or operate machinery
  • do not drink alcohol
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11
Q

Antihistamine Drugs

A
  • Cinnarizine

- Dimenhydrinate

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12
Q

Antihistamine MOA

A

interfering with the signal transmission between vestibular apparatus of the inner ear and the vomiting centre of hypothalamus

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13
Q

Dosing for Cinnarizine

A

PO 25mg at least 1/2 hr before travelling, repeated every 6 hours

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14
Q

Side effects for Cinnarizine

A

drowsiness

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15
Q

Counselling points for Cinnarizine

A
  • can cause drowsiness, do not drive/operate machines

- do not drink alcohol

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16
Q

Side effects for Dimenhydrinate

A

drowsiness, dizziness, dry mouth

17
Q

counselling points for dimenhydrinate

A
  • can cause drowsiness, do not drive/operate machineries

- do not drink alcohol

18
Q

Selective 5HT3-receptors antagonist drugs

A
  • ondansetron
19
Q

side effect of ondansetron

A

constipation, fatigue, headache, malaise (discomfort)

PPP (14 decks)

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