Genetics and Heredity Flashcards

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1
Q
Sickle cell anemia is an example of which of the following:
Incomplete dominance
Epistasis
Nondisjunction
Complete Dominance
Pleiotropy
A

Sickle cell anemia is an example of pleiotropy. Pleiotropy occurs when the expression of one gene ends up affecting the functioning of others. For example, in a person with sickle cell anemia there is a gene that is unable to properly code for hemoglobin. This abnormality causes the red blood cell to change shape (sickle shaped), which then consequently affects their ability to move throughout the body and deliver important cell-to-cell nutrients such as oxygen.

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2
Q

The calico cat is a popular example of

A

The calico cat is a popular example of x-inactivation. Remember that x-inactivation simply means one of the x-chromosomes is inactivated. Calico cats have different colors throughout their body because varying x-chromosomes have genes that are rendered to be inactive. Some are active and some are not, this causes some of the cat’s hair to be yellow, some to be black, and some white.

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3
Q

A person with type AB blood can give blood to

A

A person with type AB blood can give blood to only another person with type AB blood. If it tries to give blood to someone with type A blood for example, the type A blood will recognize the B on the AB blood as being an antigen, and will thus send out antibodies to fight against the foreign invader. Although type AB blood can receive any type of blood, it can only donate to itself. This is the opposite of the O blood type, and helps teach the differences between something that is codominant versus something that is homozygous recessive.

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4
Q

How many different alleles are there possible for blood types

A

There are three different alleles are possible for blood types; IA, IB, and i. Anytime that you see superscripts or primes used it refers to codominance, so IA and IB are codominant, while i is the recessive allele.

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5
Q

If a coin is tossed 4 times, what is the probability that you will get at least 3 tails

A

If a coin is tossed 4 times, the probability that you will get at least 3 tails is 5/16. The total possible outcomes of flipping a coin 4 times is 16 (222*2). Here are the total possible combination of getting at least 3 tails: TTTT, ThTT, TThT, TTTh, and hTTT. The other combinations that you can get are: hhhh, hhhT, hhTh, hThh, Thhh, TThh, hhTT, ThTh, hThT, hTTh, and ThhT. For a further study of probability rules go through the QR videos pertaining to probability and statistics.

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6
Q
A pea plant that is RR for red flowers is crossed with another pea plant that is homozygous recessive for white flowers, which color(s) will be expressed in the F1 generation
Pink
Red
White
All of above
A

When a pea plant that is RR for red flowers is crossed with another pea plant that is homozygous recessive for white flowers, the color(s) that will be expressed in the F1 generation will all be red. The reason that they will all be red, is because when the RR crosses with rr, all of the genotypes will be Rr (heterozygous). All of the heterozygous genotypes will thus produce red flowers.

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7
Q

How many different gametes can be produced from AaBb

A

4 different gametes can be produced from AaBb. They are as follows: AB, Ab, aB, and ab.

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8
Q
Which of the following is not an autosomal genetic defect:
Sickle-cell anemia
Phenylketonuria
Tay-sachs disease
Turner syndrome
Huntington's disease
A

Turner Syndrome is not an autosomal genetic defect, but rather a sex chromosome genetic defect. An autosomal chromosome refers to a non-sex chromosome. Turner syndrome involves the nondisjunction of sex chromosomes, whereas the other four genetic disorders are all autosomal.

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9
Q

The alleles A and A’ rather than A and a lead to the conclusion of:

A

The alleles A and A’ rather than A and a lead to the conclusion of incomplete dominance. When the A’ allele is said to be prime’ rather than showing recessive (a), it shows that there is incomplete dominance in the heterozygous expression. Neither trait will have full dominance in the heterozygous form, rather there will be a mixed phenotype expressed.

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10
Q

How many different phenotypes are available with blood

A

There are 4 different phenotypes that are available with blood, or more specifically 4 different blood group types. A, B, AB, and O expressed. While there are 6 different genotypes of blood, there are only 4 expressed phenotypes because the i allele is recessive.

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11
Q

Huntington’s Disease is

A

Huntington’s Disease is an Autosomal dominant genetic defect. With it being an autosomal dominant genetic defect, it is transferrable without both parents being carriers or there being another type of chromosome defect.

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12
Q

Color blindness is more prominent in

A

Color blindness is more prominent in males because it is a sex linked recessive condition. The genes pigments are located or carried on the X chromosome. Therefore in males (XY) it is more prominent than females (XX) because males only have one X sex chromosome that codes for this trait. If a male is a carrier it will be expressed 100% of the time, whereas if a female is a carrier it will compete with the other X chromosome.

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13
Q

A person with blood type O can receive blood from

A

A person with blood type O can receive blood from only another person with type O blood. The reason a person with type the type O blood type cannot receive blood from types A, B, or AB, is because it recognizes these blood types as being foreign invaders due to their carbohydrates and will produce antibodies to attack them.

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14
Q

When a person has a gamete with an extra #21 chromosome, this is commonly referred to as

A

When a person has a gamete with an extra #21 chromosome, this is commonly referred to as Down syndrome. Another name for Down syndrome to remember is Trisomy 21. Tri meaning three, somy referring to somatic cells, and 21 referencing the number 21 chromosome.

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15
Q
If you wanted to determine the genotype of a red flowered pea plant, which of the following would you want to perform:
Test cross
Polyhybrid cross
F2 cross
Dihybrid cross
A

If you wanted to determine the genotype of a red flowered pea plant, you would want to perform a test cross. With the dominant phenotype expressed (red flowers), you do not know what the genotype is. The best way to determine this is to perform a test cross and observe which phenotypes are expressed in the offspring. If you don’t get any white offspring, then you would say that it is highly likely that the red flowered plant is homozygous dominant.

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16
Q

Say a person has a hypothetical gene that codes for hair and another for color. When the hair gene inactivates the hair color to be expressed, this is referred to as

A

Say a person has a hypothetical gene that codes for hair and another for color. When the hair gene inactivates the hair color to be expressed, this is referred to as epistasis. Epistasis simply refers to the event where the results of one gene directly deals with the activation (or lack thereof) of another. If a hypothetical person has no hair, then hair color is irrelevant because its phenotype cannot be expressed.

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17
Q
Collectively the different blood types display all of the following with the exception of:
Complete dominance
Codominance
Incomplete dominance
Homozygous recessive
None of above
A

Collectively the different blood types display all of the following with the exception of incomplete dominance. Complete dominance is showed in both type A and type B blood types when paired with the recessive (i) allele. Codominance is expressed in the blood type AB. Homozygous recessive is shown in blood type O (ii). There is no example of incomplete dominance in blood types.

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18
Q

When two people are carriers for a genetic defect that is autosomal recessive, and they subsequently have four children. How many of their children will hypothetically inherit the genetic defect

A

When two people are carriers for a genetic defect that is autosomal recessive, and they subsequently have four children, they will hypothetically have one of their four children inherit the genetic defect (25%).

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19
Q

In a genetic cross, if red flowered pea plants are crossed with white flowered pea plants. And, the first offspring produces all red flowered pea plants, what will be the F2 generation genotypic ratio

A

In a genetic cross, if red flowered pea plants are crossed with white flowered pea plants. And, the first offspring produces all red flowered pea plants, the F2 generation genotypic ratio will be 1:2:1. When knowing that all of the F1 generation pea plants have red flowers, it is obvious that the parental red flowered pea plant is homozygous dominant. All of the white flowered pea plants are recessive, so with these things known, all of the F1 generation pea plants are heterozygous. When the heterozygous F1 generations cross, you will get a ratio of 1 homozygous dominant, 2 heterozygous and 1 homozygous recessive plants (1:2:1 ratio).

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20
Q

In the dihybrid cross of AABB x aabb, how many different genotypes are expressed in the F2 progeny

A

In the dihybrid cross of AABB x aabb, there are four different phenotypes expressed in the F2 progeny. The first thing to determine with this question is the type of genotypes in the F1 progeny. This is done by filling out the Punnett Square. When looking at the Punnett Square for the F1 progeny, you get only one genotype (AaBb, heterozygous) which results in only one phenotype. Since all of the genotypes are heterozygous, you will then cross AaBb x AaBb. As a result, you will get the following genotypic frequencies: AABB (1), AABb (2), AaBB (2), AaBb (4)—which express both dominant phenotypes. aaBB (1) and aaBb (2)—which express the recessive first trait and dominant second trait. AAbb (1) and Aabb (2)—which express the dominant first trait and recessive second trait. Aabb—which expresses both recessive traits. So out of the 16 total combinations there are 9 different genotypes expressed with 4 different phenotypes expressed.

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21
Q
Mental retardation is a common symptom of all of the following except:
Klinefelter syndrome
Down syndrome
Cri Du Chat syndrome
Turner Syndrome
A

Mental retardation is a common symptom of all of the following except Turner Syndrome. While it is possible to have mental retardation from Turner Syndrome, it is not a common effect of it.

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22
Q

When a white haired dog mates with a black haired dog, their puppies have a mix of both white and black hair. This is an example of

A

When a white haired dog mates with a black haired dog, their puppies have a mix of both white and black hair. This is an example of codominance. Codominance simply means that both traits are dominant and expressed. Instead of having grey hair (incomplete dominance), and one having black hair only (complete dominance), both are expressed (codominance).

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23
Q
What genotype is not produced from the cross of Aa by Aa:
aA
AA
Aa
aa
A

When there is a heterozygous crossed with a heterozygous, you will end up with all of the different traits in the offspring. This question is sort of tricky because although you will see the heterozygous genotype, it is incorrect to put the recessive trait before the dominant. That is why it is proper to write Aa and not aA.

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24
Q
The law of segregation:
Occurs during Mitosis.
Is a law that was discovered by Netwon.
Refers to the nonrandom segregation of alleles to offspring.
None of above.
All of above.
A

The law of segregation is a law that was discovered by Gregory Mendel while using pea plants. This law refers to the “random” segregation of alleles to offspring and occurs during Meiosis I. Make sure that you understand the difference between the law of segregation and the law of independent assortment.

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25
Q

If a pea plant’s dominant phenotype is red flowers, and its recessive phenotype is white flowers, and you observe a red flowered pea plant, what are the possible genotype of this red flowered pea plant

A

Since the red flowered pea plant is the dominant phenotype, there are two possible genotypes that can produce it: Homozygous Dominant and heterozygous. If we flip the questions and ask about the white plant, there is only one genotype that can produce the white flowered pea plant, homozygous recessive.

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26
Q

A person with type AB blood can receive blood from

A

A person with type AB blood can receive blood from all of the different blood types. This is because it is codominant, and can thus recognize A, B, AB, and O blood types as not being foreign invaders or antigens.

27
Q

A person with the blood type O can give blood to

A

A person with the blood type O can give blood to anyone. He or she is referred to as a universal donor. One way of remembering that type O is the universal donor is that the shape of an O is circular or universal in its nature. Blood type O has neither an A or B carbohydrate present, therefore all of the blood types will accept blood type O.

28
Q

When a monohybrid cross occurs between a heterozygous plant along with the homozygous recessive plant, what is the ratio of the dominant phenotype to the recessive trait express

A

When a monohybrid cross occurs between a heterozygous plant along with the homozygous recessive plant, the ratio of the dominant phenotype to the recessive phenotype is 2:2, which is the same as a 1:1 ratio. You will get two heterozygous (dominant trait expressed plants), along with two homozygous recessive ones.

29
Q

A dihybrid cross involves

A

A dihybrid cross involves the analyzing of genes for two different traits. For example with pea plants, a dihybrid cross might involve looking at the genes for flower color and seed type. A monohybrid cross would just involve the analysis of one trait such as flower color.

30
Q

In the dihybrid cross of AABB x aabb, what is the phenotypic ratio of the F2 progeny

A

In the dihybrid cross of AABB x aabb, the phenotypic ratio of the F2 progeny is 9:3:3:1. That is there are 9 genotypes that express both dominant phenotypes together. 3 genotypes for each hetero expressions, and 1 genotypes that has both recessive phenotypes expressed.

31
Q

If a person is a carrier for a genetic defect that is autosomal dominant, and they subsequently have four children with someone who is not a carrier. How many of their children will hypothetically inherit the genetic defect

A

If a person is a carrier for a genetic defect that is autosomal dominant, and they subsequently have four children with someone who is not a carrier, they will hypothetically have two of their four children inherit the genetic defect (50%).

32
Q

In the dihybrid cross of AABB x aabb, how many different genotypes are expressed in the F1 progeny

A

In the dihybrid cross of AABB x aabb, there is only 1 different genotype expressed in the F1 progeny—AaBb. All of the F1 progeny will be heterozygous for both traits (AaBb), which means that there will only be one phenotype expressed—the dominant traits for both alleles.

33
Q

___ have the ability to determine specific traits that have the potential to be passed on from parents to their offspring.

A

Alleles have the ability to determine specific traits that have the potential to be passed on from parents to their offspring. An allele is simply a specific variation of a gene. In flowers for example, you might see a white allele and a green allele. The white allele codes for white flowers, while the green allele codes for green flowers.

34
Q
The height of humans is an example of which of the following:
Pleiotropy
Nondisjunction
Polygenic inheritance
Epistasis
Linked genes
A

The height of humans is an example of polygenic inheritance. There is not one gene that simply regulates the height of humans (for example a short gene and a small gene), but there is rather a relationship between many genes that give rise to the actual height of a person. This is why there are both varying and relatively similar heights among people.

35
Q

In the dihybrid cross of AABB x aabb, how many different phenotypes are expressed in the F1 progeny

A

In the dihybrid cross of AABB x aabb, there is only 1 different phenotype expressed in the F1 progeny—Dominant traits. All of the F1 progeny will be heterozygous for both traits (AaBb), which means that there will only be one phenotype expressed.

36
Q

A pea plant with red flowers is crossed with one that has white flowers, which color(s) will be present in the F1 progeny

A

When a pea plant with red flowers is crossed with one that has white flowers, the color(s) that will be present in the progeny cannot be determined because the genotypes are not given. In order to determine the phenotypes or expression of the genes (colors), it must be determined which type of alleles are present. For example the red flowers could be either homozygous dominant or heterozygous.

37
Q

A genetic cross is done between 2 different plants and involves the analysis of 1 genetic trait, which type of cross is this

A

When a genetic cross is done between 2 different plants and involves the analysis of 1 genetic trait, it is a monohybrid cross. A monohybrid cross simply refers to the examination of one genetic trait (example; flower color).

38
Q

Nondisjunction:
Frequently results in genetic defects.
Occurs when chromosomes do not correctly separate.
Results in gametes with incorrect numbers of chromosomes.
None of above.
All of above.

A

Nondisjunction occurs when chromosomes do not correctly separate, frequently results in genetic defects, and also results in gametes with incorrect numbers of chromosomes.

39
Q

How many different genotypes are available with blood

A

6 different genotypes are available with blood, they are as follows: ii, IAIA, IBIB, IAIB, IAi, and IBi.

40
Q

The probability that a gene crosses over with another gene on the same chromosome increases as

A

The probability that a gene crosses over with another gene on the same chromosome increases as they are located farther apart. The closer a gene is to another gene on the same chromosome, the least likely it is to break off and cross over during the process of synapsis. The distance between chromosomes is important to study when looking at genetics.

41
Q

If a coin is tossed 6 times, the probability that you will get 6 heads

A

If a coin is tossed 6 times, the probability that you will get 6 heads is 1/64. This problem involves six tosses of a coin. Each toss has a ½ chance of being heads, therefore taking ½ and multiplying it by the number of total coin tosses (6), will yield 1/64 ( ½ * ½ * ½ * ½ * ½ * ½ ). For a further study of probability rules go through the QR videos pertaining to probability and statistics.

42
Q

If a coin is tossed 6 times, the probability that the 5th toss will be tails is

A

If a coin is tossed 6 times, the probability that the 5th toss will be tails is ½. The reason that it is ½ or 50% is because each toss is independent of each other. Questions about genetics involve a proper understanding of probability. For a further study of probability rules go through the QR videos pertaining to probability and statistics.

43
Q
X-Inactivation:
Involves Carr bodies
Renders both x-chromosomes inactive. 
Develop during early embryonic stages.
All of above
None of above
A

X-Inactivation involves Barr bodies, renders one of the x-chromosomes inactive, and do develop during early embryonic stages.

44
Q

In a Punnett Square, how many possible combinations (not different) are there in a dihybrid cross

A

In a Punnett Square, there are 16 possible combinations or boxes in a dihybrid cross. If you have a cross between the genotypes AABB x AABB, you would have 16 total combination boxes in the Punnett Square and all of them would be AABB.

45
Q

What two genetic disorders are necessary for a male cat to be Calico?

i. Klinefelter syndrome
ii. Cri Du Chat syndrome
iii. Down syndrome
iv. Turner syndrome
v. X-inactivation

A

The calico cat is a result of x-inactivation, that is one of the X chromosomes out of the two is a Barr body and inactive. This causes some of the genes to be turned on and others to be turned off, rendering the cat spotted or calico in color throughout. Calico cats are typically not males, because in order for a male to be calico it must have XXY chromosomes; it must have two X chromosomes but also be a male. This is what is commonly referred to as Klinefelter’s Syndrome, and results in the male calico cat when combine with x-inactivation.

46
Q
Which of the following genetic disorders would someone have if they were experiencing muscle deterioration and increased difficulties in their hand eye coordination:
Duchenne's
Cri Du Chat Syndrome
Color Blindness
Hemophilia
Down Syndrome
A

If someone was experiencing muscle deterioration and increased difficulties in their hand eye coordination they could potentially have Duchenne’s Muscular disorder. Duchenne’s is a sex linked dominant disorder and involves the absence of a necessary muscle protein.

47
Q

Which law refers to the fact that homologous chromosomal pairs along with their genes segregate independently in respect to others

A

The law of independent assortment refers to the fact that homologous chromosomal pairs along with their genes segregate independently in respect to others.

48
Q
Hemophilia is:
an example of pleiotropy.
the same to inherit in both male and female.
an example of epistasis.
easier to inherit as a male.
easier to inherit as a female.
A

Hemophilia is easier to inherit as a male. Being that Hemophilia is an x-linked and recessive gene, it takes the inheritance of both of a female’s x-chromosomes to possess hemophilia. With males only having one x-chromosome, whatever gene is present on the x-chromosome is expressed even though it is a recessive gene. Therefore, hemophilia is more prevalent in males than females.

49
Q

In the dihybrid cross of AABB x aabb, how many different ohenotypes are expressed in the F2 progeny

A

In the dihybrid cross of AABB x aabb, there are four different phenotypes expressed in the F2 progeny. The first thing to determine with this question is the type of genotypes in the F1 progeny. This is done by filling out the Punnett Square. When looking at the Punnett Square for the F1 progeny, you get only one genotype (AaBb, heterozygous) which results in only one phenotype. Since all of the genotypes are heterozygous, you will then cross AaBb x AaBb. As a result, you will get the following genotypic frequencies: AABB (1), AABb (2), AaBB (2), AaBb (4)—which express both dominant phenotypes. aaBB (1) and aaBb (2)—which express the recessive first trait and dominant second trait. AAbb (1) and Aabb (2)—which express the dominant first trait and recessive second trait. Aabb—which expresses both recessive traits. So out of the 16 total combinations there are 9 different genotypes expressed with 4 different phenotypes expressed.

50
Q
Which of the following genetic defect is most similar to Down syndrome in the way that they occur:
Huntington's disease
Cri Du Chat syndrome
Tay-Sachs disease
Hemphilia
Turner syndrome
A

Turner syndrome is a genetic defect that is most similar to Down syndrome because they both occur as a result of nondisjunction. In Turner syndrome you have the nondisjunction of the sex chromosomes, whereas in Down syndrome you have the nondisjunction of chromosome 21.

51
Q
When looking at a heterozygous plant, you notice that its color is pink. What are the possible parental alleles that gave rise to this specific phenotype?
Red only
Pink only
White only
Red and White 
All of above
A

When looking at a heterozygous plant, you notice that its color is pink. The possible parental alleles that gave rise to this specific phenotype are red and white. Knowing that the plant is heterozygous, you know that both alleles are hetero or different. Therefore you couldn’t have two pink alleles, or two white alleles, or two red alleles giving rise to the pink color, it would have to be two different alleles. When two alleles give rise to a phenotype that neither has, there is no dominant or recessive behavior, and this is better known as incomplete dominance.

52
Q
Which of the following monohybrid crosses would result in an equal ratio of phenotypes to genotypes in the F1 generation:
Homo dom x Homo dom
Homo rec x Hetero
Hetero  x Homo dom
Hetero x Hetero
More than one of the above
A

When looking for monohybrid crosses that would result in an equal ratio of phenotypes to genotypes in the F1 generation, you must first determine the possible genotypes. For this question there are three genotypes, Aa, AA, and aa. There are only two phenotypes available, the dominant trait expressed along with the expression of the recessive trait. When a heterozygous crosses with a homozygous dominant, you will get two different types of genotypes in the F1 generation, but only one phenotype. When a heterozygous is crossed with a heterozygous, you will get all three genotypes, so this is not a possible answer either. A homozygous dominant crossed with another homozygous dominant will give you 1 genotype and 1 phenotype. A homozygous recessive crossed with a heterozygous will give you 2 types of genotypes and 2 types of phenotypes, so this is also an answer.

53
Q

Curly hair amongst humans is an example of

A

Curly hair amongst humans is an example of incomplete dominance. In humans neither straight or curly hair is completely dominant over the other, so when the heterozygous form is present, instead of taking the dominant form it takes a form in the middle—wavy hair.

54
Q

When a gene has two different alleles, and one is dominant while the other is recessive, which allele is the trait that is expressed?

A

When a gene has two different alleles, and one is dominant while the other is recessive, the dominant allele is the trait that is expressed. Anytime the word dominant is used in regards to a specific allele, it refers to the fact that it is a dominating allele over the recessive trait, therefore you can eliminate other options such as incomplete dominance.

55
Q

Genetic material or segments of DNA that are sited on chromosomes and give trait instructions are termed

A

Genetic material or segments of DNA that are sited on chromosomes and give trait instructions are termed genes. Again word associations will really help you remember terms on test day, which is why it is good to associate genes with genetic material.

56
Q

Females have __ sex chromosomes whereas males have __ sex chromosomes.

A

Females have XX sex chromosomes whereas males have XY sex chromosomes.

57
Q

A red flowered parental pea plant with the genotype Pp produces what gametes

A

A red flowered parental pea plant with the genotype Pp produces P and p gametes. In the Pp red flowered pea plant, there is a pair of homologous chromosomes that end up migrating to opposite poles in division. After the gametes are developed, they then come together with another gamete to form a zygote which gives rise to specific phenotypes.

58
Q

What type of genes cannot independently segregate

A

Linked genes cannot independently segregate. The reason that they cannot segregate is because they are located on the same chromosome and as a result cannot be physically separated. Genes that are physically close to each other are as a result inherited together.

59
Q
A person with XO sex chromosomes has which of the following genetic disorders:
hemophilia
down syndrome
cri du chat syndrome
klinefelter syndrome
turner syndrome
A

A person with XO sex chromosomes has turner syndrome. Because of nondisjunction, gametes can lack their sex chromosome or have an extra, which when absent is labeled as an O. In a person with turner syndrome, they are missing a chromosome from one parent and receive the X from either the father or the mother.

60
Q

Cri Du Chat syndrome occurs as a result of

A

Cri Du Chat syndrome occurs as a result of the deletion of chromosome 5. People who have Cri Du Chat syndrome results in retardation and produce a catlike cry in children.

61
Q

In the dihybrid cross of AABB x aabb, what is the phenotypic ratio of the F1 progeny

A

In the dihybrid cross of AABB x aabb, the phenotypic ratio of the F1 progeny is 16:0:0:0. With the cross AABB x aabb you will get all heterozygous in the first generation offspring. This results in one phenotype expressed; both being dominant traits.

62
Q

When a cell has two copies of a chromosome, and these copies code for the same specific trait at the same specific genetic loci, they are referred to as

A

When a cell has two copies of a chromosome, and these copies code for the same specific trait at the same specific genetic loci, they are referred to as homologous pairs. Within each homologous pair, one chromosome is inherited from the mother, while the other chromosome is inherited from the father.

63
Q

Each chromosome has a specific location where genes are, this location is known as the gene’s ___.

A

Each chromosome has a specific location where genes are, this location is known as the gene’s locus. I always associate the term locus with location to remember this term.