genetic information (RNA and protein synthesis) Flashcards
what does mRNA stand for?
messenger RNA
when is mRNA made?
during transcription
what does mRNA do?
carries the genetic code from the DNA to the ribosomes, where it makes a protein in translation
what is a group of 3 bases called in mRNA?
codons
what does tRNA stand for?
transfer RNA
what does tRNA do?
used in translation
carries the amino acids to the ribosomes
what is the structure of tRNA?
single polynucleotide clover shape hydrogen bonds between base pairs anticodon amino acid binding site
what is a sequence of 3 bases called in a tRNA molecule?
anticodon
what are the stages of transcription?
DNA helix unwinds to expose bases and act as a template
chain of DNA acts as a template
catalysed by DNA helicase
which breaks hydrogen bonds between bases
free mRNA nucletoides in the nucleus align with exposed complementary bases
RNA polymerase bonds RNA nulceotides by phosphodiester bonds
pre mRNA spliced to form mRNA
mRNA moves out of the nuclear pore and attaches to a ribosome in the cytoplasm
what are the stages of translation?
mRNA attaches to a ribosome at the start codon
tRNA has an anticodon complementary to the mRNA codon
tRNA brings along a specific amino acid
amino acids joined by peptide bonds using ATP
tRNA released
ribosome moves along mRNA to form a polypeptide
detaches at the stop codon
enters the golgi for folding and modification
what is genetic diversity?
the number of different alleles of genes in a species/population
what is genetic diversity in a population increased by?
mutations in the DNA
different alleles being introduced to a population after migration (gene flow)
what is a genetic bottleneck?
event that causes a big reduction in a population
why does a genetic bottleneck reduce genetic diversity?
reduces the number of alleles in the gene pool, survivors reproduce and a larger population is created from fewer individuals
what is the founder effect?
type of genetic bottleneck where there is only a small number of alleles in the initial gene pool