Genes and DNA Flashcards

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1
Q

What is a gene?

A

sequence of nucleotides that codes for rRNA, tRNA or single polypeptide via an mRNA intermediate.
eukaryotes have more than 1 copy of some genes while prokaryotes have only 1 copy.

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2
Q

what is euchromatin?

A

eukaryotic genes that being actively transcribed by a cell

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3
Q

what is heterochromatin?

A

genes that are not being actively transcribed.

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4
Q

what is genome?

A

entire DNA sequence of an organism

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5
Q

what is the central dogma?

A

the central dogma is that DNA is transcribed to RNA which is translated to aa forming a protein.

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6
Q

what does DNA stand for ?

A

deoxyribonucleic acid

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7
Q

what is DNA?

A

Polymer of nucleotides. DNA nucleotides differ from each other only in the nitrogenous base.

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8
Q

what are the 4 nitrogenous bases of DNA?

A

Adenine, Guanine, Cytosine and Thymine.
A and G are two rings and called purines.
C and T are single ring and called pyrimidines.

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9
Q

how are nucleotides connected?

A

phosphodiester bond between the third carbon of one deoxyribose and the 5 carbon of the other. creates a sugar to a phosphate bond. DNA is made in a 5’ to a 3’ direction

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10
Q

DNA strands

A

are in antiparallel direction bound together by hydrogen bonds between the bases to form a double stranded structure . A and T form 2 hydrogen bonds with each other. G and C form 3 hydrogen bonds with each other. the two DNA strands are complementary strands, they curl into a double helix.

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11
Q

what are the two grooves?

A

the double helix has two distinct grooves, the major and the minor.

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12
Q

what is each nucleotide made up of ?

A
a phosphate group
a 5 carbon sugar 
and a nitrogenous base. 
know that AT pair and GC pair 
and that RNA docent have T it has U or Uracil instead ( which is a pyrimidine)
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13
Q

what does RNA stand for ?

A

ribonucleic acid

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14
Q

how is RNA different from DNA?

A

Carbon 2 on pentose is not deoxygenated ( it has a OH hydroxyl group)
RNA is single stranded
RNA has U. instead of T
RNA can also move through nucleus pores and is not confirmed to the nucleus.
DNA is made by replication and RNA is made by transcription.

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15
Q

what are 3 important types of RNA?

A

mRNA (messenger)- deliver DNA code for amino acids to the cytosol where proteins are made
rRNA (ribosomal)- combines with proteins to form ribosomes. - rRNA is made in the nucleolus.
tRNA (transfer) - collects amino acids in the cytosol and transfers them to ribosomes for incorporation into a protein.

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