General Virology+ DNA Viruses Flashcards
What’s meaning of recombination
Exchange of gene between 2 chromosomes by crossing over
Whats meaning of Complimentaion
Virus complement the other to work (example Hepatitis B and Hepatitis D)
Whats meaning of phenotypic mixing?
When two viruses infect the same cell at the same time
Types of viral vaccine
- Live attenuated
2. Killed
Live attenuated vaccine for which viruses?
فرخه صفرا سايبينها في الممر ببوكس صغير مع روتافايروس
Killed vaccine for which viruses
RIP Always
- Rabies
- influnza-injected
- Polio virus(salk)
- Hepatitis A virus
All DNA viruses are dsDNA except:
Parvovirus
All RNA viruses are ssRNA except:
Reovirus
(+) stranded RNA viruses:
Corona FC THRP
- Corona
- Flavi-virus
- calici-virus
- toga-virus
- hepe-virus
- Retro-virus
- Picorna-virus
(-) stranded RNA viruses:
FAR-BOP
- Filo-virus
- Arena-virus
- Rhabdovirus
- Bunya-virus
- Orthomyxovirus
- Paramyxovirus
all DNA viruses replicated in the nucleus except:
Poxvirus
all the RNA viruses replicated in the cytoplasm except:
- Paramyoxivirus
2. Retrovirus
Which DNA viruses are circular?
- Papilloma
- Polyoma
- Hepadnavirus (ex:HBV)
Naked(non-enveloped) DNA viruses:
PAPP
- Papilloma
- adenovius
- polyoma
- parvovirus
Naked(non-developed) RNA viruses:
CHPR
- calici-virus
- hepe-virus
- picorna-virus
- Reo-virus
General DNA viruses
HHAPPPPy
Herpes,hepadna,adenovirus,papilloma,polyoma,poxvirus,parvovirus
Types of herpes virus:
- HSV-1
- HSV-2
- VSV
- EBV
- cytomegalovirus
- HHV-6,7
- HHV-8
HSV-1 primary infection:
Gingivostomatitis
HSV-1 reactivation, cause:
Cold sores
HSV-1 diseases:
- gingivo-stomatitis(primary infection).
- Kerato-conjunctivitis.
- Herpes labialis (secondary infection).
- Temporal lobe encephalitis
- Esophagitis
HSV-1 temporal lobe encephlitis symptomes:
- Acute onest of fever
- Aphasia عدم القدره على الكلام
- seizure
- headache
HSV-2 diseases
- Herpes genetalis : pustules and ulcer on labia, penis, buttocks
- Neonatal herpes
VZV diseases
- Chickenpox
- Shingles
- herpes zoster
Herpes zoster symptomes
- Unilateral veiscular rash
- Pain that persists for several months.
- Dermatom destruction
Latent form of VZV
Herpes zoster
Primary infection of VZV
Chickenpox
Which type of disease of VZV the immune system produce IgG aginst it ?.
Chickenpox
Which virus infect B-cell?
EBV
Which viruse cause mononucleosis?
EBV
Symptomes of mononucleosis
- Fever
- Hepatospleenomegally
- Pharyngitis
- Lymphoadenopathy
Symptomes of congenital CMV
- Deafness
- Jaundice
- Seizures
- Hepatospleenomegally
CMV diseases
CHVER-P
- Pneumonea( in transplant patient)
- Esophagitis
- Retinitis(AIDS)
- Hemorrhage
- Vission loss
- Cotton-wool exudate
Which viruse cause roseola infantum?
HHV-6
Symptomes of Roseola infantum:
- High fever(3-5 days)
- Seizures
- Diffuse maculopapular rash
Which viruse case capusi sarcoma?
HHV-8
Capusi sarcoma seen in ?
- HIV
- AIDS
- Transplant patient
What’s capusi sarcoma?
Neoplasm of endothelium cell
Kaposi sarcoma result in:
- Vascular proliferation
2. Dark violaceus plaque of nodules
Disease of pox-virus
- Smallpox
2. Crowpox (milk-maid blister)
Which virus cause molluscum contagrosum?
Crowpox of poxvirus
HBV for which group of viruses?
Hepadna-virus
Diseases of adeno-virus
- Acute hemorrhagic cystits (in children)
2. Pharyngio-conjunctival fever
Pharyngio-conjunctival fever symptomes :
- Fibrile pharyngitis
- Fever
- Conjunctvitis
- Nasal congestion
- Cough
Human papilloma virus 1-4 cause:
Skin wart ( verruca vulgaris )
Human papilloma virus 6,11 cause
Genital wart (condylomata acuminata)
Human papilloma virus 16,18 cause:
Neoplasia in :
- Anal
- Cervical
- Vaginal
- Vulvar
Parvo-virus {B-19} cause in normal child:
Erythema infectiousum ( slapped cheecks )
Parvo-virus {B-19} cause in normal adult :
Acute systemic arthropathy
Parvo-virus {B-19} cause in general
Chonic hemolytic anemia