general suger . Youve Got To Be KIDding NEY Flashcards
Pre renal kidney injury causes
Main
And so
Reduced blood flow
Blood loss D and v Heart failure/attack Nsaids reduce prostaglandins so vasoconstriction prevented Allergies- histamine vasodilator
Renal kidney injury causes
Main
Then
Kidney ugh Sepsis (infection) - inflammation Tumours Tubular necrosis nephritis Vasculitis (stiff )
Post renal kidney injury causes
Main
Also
Blockage of urinary tract
Tumours- bladder kidney prostae (inc benign prostate enlargement)
Kidney stones
Blood clots
chorion=
outermost layer of trophoblasts
where chorionic villi project from
septum= (placenta)
protruding part of mother’s endometrium, un’eroded’ by chorionic villi enzymes, seperates pools of placental sinus/mothers blood around chorionic villi
decidua
part of mother’s endometrium in placenta- layer below the septums and maternal blood in intervillous space
which mucus helps and which hinders sperm transport
helps= thin, alkaline, secreted in proliferative/follicular phase (1-14)
hinders= thick, acidic, secreted in luteal phase (15-28), prevents polyspermy
labour : chain reaction
fetus–> ant pit –> ACTH –> placenta –> less prog, more oes —> prostaglandins (from uterine tissues) increase –> oxytocin (from post pit) increase –> uterine contraction
when hcg, oes and prog high in pregnancy
roles of hcg, oes, prog in pregnancy
hcg- spike early on.
- produced by trophoblasts
- matures placenta
- maintains corpus luteum and stimulates its production of oes and prog
oes and prog- low at start, then rise, oes higher than prog
- stops progressive menstrual cycles (hpg axis: low gnrh so low fh and lsh)
-oes : stimulates uterine muscle growth
, prepares breasts
- prog: inhibits uterine muscle contraction (prevents miscarriage)
- maintains thick endometrium
morula
ball of cells (16 ish)
totipotent
before=zygote
blastocyst
from morula/blastula
two distinct layers- outer= trophectoderm (made from trophoblasts) inner= inner cell mass - embryonic
blastula
after morula, before blastocyst
post fertilisation stages order
capacitation (sperm) acrosomal reaction cortical granules released syngamy (pronuclei fuse (pronuclear membranes break down)) cleavage morula blastocyst compaction hatching (zone pellucida breaks down) implantation
compaction=
cells of blastocyst flatten, tight junctions, sona pellucida thins, outer cells polarized
implantation stages
apposition (orientation)
attachment (adhesions from trophoblast projections)
invasion (chorionic villi –> placenta)