Gastrointestinal patologi Flashcards

1
Q

Beskriv kort patogenes av en magsår pga HP.

A

HP (proteaser, fosfolipaser, ammonia) -> inflammation -> produktion av cytokiner

leder till

  1. gastrin stimulering
  2. undertryckt somatostatin

-> Magsår

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2
Q

Vad händer om HP finns i antrum?

A
  1. Ökad gastrin
  2. Ökad HCl (minskad pH)
  3. Duod. pH minskar
  4. Duedonit (HP)
    Ulcus deodeni
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3
Q

Vad händer om HP finns i högre upp i magsäcken och orsakar gastrit?

A
  1. Pangastrit
  2. Parietalceller minskar
  3. HCl minskar (pH ökar)
  4. pH=2 => intestinal metaplasi
  5. Bakterier trivs
  6. Nitrat -> Nitrit -> Nitrocaminer
    CANCER
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4
Q

Kronisk ulcus (peptic) i ventrikle

A
Ventrikel ulcus
Äldre 
Kön 2/1
Minskad HCl
Pangastrit
HB 70%
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5
Q

Kronisk ulcus (peptic) i duodenum

A
Duedenal ulcus
40år
Kön 7/1
Antrum
HB 90%
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6
Q

Malabsorption: Luminal fas

A
  1. Pankreas dysfunktion
  2. Störd gallutsöndring
  3. Brist på gallstenar
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7
Q

Malabsorption: Intestinal fas

A
  1. Dysfunktion av mikrovilli
  2. Minskad absorptionsyta
  3. Metabol dysfunktion i de absorberande cellerna
  4. Störd transport av nutrienter
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