Gastroenterology Flashcards
Hepatitis B status:
- Anti HBs positive. All other tests negative
Previous immunisation
Hepatitis B status:
- Anti HBc positive. HBsAg negative
Previous infection not a carrier
Hepatitis status: Anti Hbc IgG positive, HbsAg positive. Negative anti HbC IgM and anti Hbs
Chronic Hep B infection
Treatment of recurrent C Diff within 12 weeks of symptom resolution
Fidaxomicin
Investigation of choice for suspected perianal fistulae
MRI pelvis - used to etermine whether the fistula is simple or complex
Antibodies present in Primary biliary cholangitis
Anti mitochondrial antibodies
Management of primary biliary cholangitis
Urseodeoxycholic acid
What is barrats oesophagus?
Metaplasia of the lower oesophageal mucosa with the squamous epithelium being replaced by columnar epithelium
What is the most common extra intestinal feature in crohns disease and ulcerative colitis?
Arthritis
In Crohns and UC which extrarticular manifestations are related to disease activity.
Arthritis (asymmetrical)
Erythema nodosum
Episcleritis
Osteoporosis
In crohns and UC what extracurricular manifestations are unrelated to disease activity
Arthritis (symmetrical)
Uveitis
Pyoderma gangrenosum
Clubbing
Primary sclerosing cholangitis
First line test for H Pylori
Urea breath test.
What test can be used to confirm H Pylori eradication
Urea breath test
What cancer are yoy at increased risk of if you have coeliac disease
Enteropathy associated T cell lymphoma of the small intestine
What is the double duct sign on MRCP and what does it mean?
Dilatation of the common bile duct and the pancreatic duct – indicitive of pancreatic cancer
Investigation of choice for suspected pancreatic cancer
High resolution CT scanning
First line to achieve remission is crohns disease
Steroids
First line to maintain remission in crohns disease
Azathioprine
Most common cause of hepatocellular carcinoma in the UK
Hepatitis C
Are granulomas seen in crohns or UC
Crohns
What is melanosis coli associated with?
Laxative abuse
Are goblet cells associated with crohns or UC?
Crohns
What is peutz jeghers syndrome
Autosomal dominant condition characterised by numerous hamartomatous polyps in the GI tract. Also associated with pigmented frckles on the lips, face, palms and soles.
Inheritence pattern of hereditary haemachromatosis
Autosomal recessive
Treatment for wilsons disease
Penicillamine
HLA subtype in coeliac disease
HLA DQ2 and HLA DQ8
When do PPIs have to be stopped prior to GI endoscopy
2 weeks before an upper GI endoscopy
Is total iron binding capacity low or high in Iron deficiency anaemia?
High
Is total iron binding capacity low or high in anaemia of chronic disease?
Low or normal
Blood tests for monitoring haemachromatosis
Transferrin saturation (below 50%) and serum ferritin (below 50)
Antibodies in autoimmune hepatitis
ANA
Anti smooth muscle antibodies
What malignancy is associated with H Pylori
MALT Lymohoma
Mucosa associated lymphoid tissue
Type of oesophageal cancer more likely to develop in patients with a hostory of GORD or Barrets oesophagus
Adenocarcinoma
Investigation for local staging of oesophageal cancer
Endoscopic USS
What type of oesophageal carcinoma is seen more commonly in patients with achalasia
Squamous cell
Where is the oesophagous do you get adenocarcinoma
Lower third
Where in the oesophagus do you get Squamous cell carcinoma
Upper two thirds
