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MSRA > Gastroenterology > Flashcards

Gastroenterology Flashcards

1
Q

Hepatitis B status:
- Anti HBs positive. All other tests negative

A

Previous immunisation

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2
Q

Hepatitis B status:
- Anti HBc positive. HBsAg negative

A

Previous infection not a carrier

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3
Q

Hepatitis status: Anti Hbc IgG positive, HbsAg positive. Negative anti HbC IgM and anti Hbs

A

Chronic Hep B infection

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4
Q

Treatment of recurrent C Diff within 12 weeks of symptom resolution

A

Fidaxomicin

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5
Q

Investigation of choice for suspected perianal fistulae

A

MRI pelvis - used to etermine whether the fistula is simple or complex

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6
Q

Antibodies present in Primary biliary cholangitis

A

Anti mitochondrial antibodies

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7
Q

Management of primary biliary cholangitis

A

Urseodeoxycholic acid

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8
Q

What is barrats oesophagus?

A

Metaplasia of the lower oesophageal mucosa with the squamous epithelium being replaced by columnar epithelium

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9
Q

What is the most common extra intestinal feature in crohns disease and ulcerative colitis?

A

Arthritis

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10
Q

In Crohns and UC which extrarticular manifestations are related to disease activity.

A

Arthritis (asymmetrical)
Erythema nodosum
Episcleritis
Osteoporosis

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11
Q

In crohns and UC what extracurricular manifestations are unrelated to disease activity

A

Arthritis (symmetrical)
Uveitis
Pyoderma gangrenosum
Clubbing
Primary sclerosing cholangitis

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12
Q

First line test for H Pylori

A

Urea breath test.

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13
Q

What test can be used to confirm H Pylori eradication

A

Urea breath test

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14
Q

What cancer are yoy at increased risk of if you have coeliac disease

A

Enteropathy associated T cell lymphoma of the small intestine

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15
Q

What is the double duct sign on MRCP and what does it mean?

A

Dilatation of the common bile duct and the pancreatic duct – indicitive of pancreatic cancer

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16
Q

Investigation of choice for suspected pancreatic cancer

A

High resolution CT scanning

17
Q

First line to achieve remission is crohns disease

A

Steroids

18
Q

First line to maintain remission in crohns disease

A

Azathioprine

19
Q

Most common cause of hepatocellular carcinoma in the UK

A

Hepatitis C

20
Q

Are granulomas seen in crohns or UC

A

Crohns

21
Q

What is melanosis coli associated with?

A

Laxative abuse

22
Q

Are goblet cells associated with crohns or UC?

A

Crohns

23
Q

What is peutz jeghers syndrome

A

Autosomal dominant condition characterised by numerous hamartomatous polyps in the GI tract. Also associated with pigmented frckles on the lips, face, palms and soles.

24
Q

Inheritence pattern of hereditary haemachromatosis

A

Autosomal recessive

25
Q

Treatment for wilsons disease

A

Penicillamine

26
Q

HLA subtype in coeliac disease

A

HLA DQ2 and HLA DQ8

27
Q

When do PPIs have to be stopped prior to GI endoscopy

A

2 weeks before an upper GI endoscopy

28
Q

Is total iron binding capacity low or high in Iron deficiency anaemia?

A

High

29
Q

Is total iron binding capacity low or high in anaemia of chronic disease?

A

Low or normal

30
Q

Blood tests for monitoring haemachromatosis

A

Transferrin saturation (below 50%) and serum ferritin (below 50)

31
Q

Antibodies in autoimmune hepatitis

A

ANA
Anti smooth muscle antibodies

32
Q

What malignancy is associated with H Pylori

A

MALT Lymohoma
Mucosa associated lymphoid tissue

33
Q

Type of oesophageal cancer more likely to develop in patients with a hostory of GORD or Barrets oesophagus

A

Adenocarcinoma

34
Q

Investigation for local staging of oesophageal cancer

A

Endoscopic USS

35
Q

What type of oesophageal carcinoma is seen more commonly in patients with achalasia

A

Squamous cell

36
Q

Where is the oesophagous do you get adenocarcinoma

A

Lower third

37
Q

Where in the oesophagus do you get Squamous cell carcinoma

A

Upper two thirds

MSRA (21 decks)

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