Gas Transport Flashcards
Where does carbon dioxide bind in the blood
To the globin
The maximum amount of O2 that can be combined with Hb is called the
O2 capacity
The percentage of the available binding sites that have O2 attached to Hb
O2 saturation
What does a shift to the right mean on hemoglobin saturation
Lower affinity of oxygen
What does 2,3 BPG due to oxygen
Reduces affinity
What is the Bohr effect
When CO2 lowers the affinity of O2 by stabilizing the T state of Hb
Hb traveling from high to low pH releases O2
Hb S has _____ instead of glutamic acid
Valine
How do you treat a patient with carboxyhemoglobin
Put patient on 100% O2
Which way will it shift if patient has carbon monoxide posioning
Left
What color does someome with carbon monoxide turn
Red
Small changes in PCO2 results in _______ amounts of Co2 to loaded and unloaded
Large
What is the haldane effect
In the presence of high blood O2, there will be less affinity of Hb to Co2 leading to the dissociation of carbaminohemoglobin and unloading of Co2 (in lung)
What is another name for hypercapnia
Acidosis