Antibodies Flashcards
where do T cells reside
paracortex
BTK is involved in
B cell maturation
what do high levels of TGIF-B do
stimulate MALT to secrete IgA
what does the brambell receptor do (FcRB)
Allows IgG to be transported across the placenta
why dont you test a baby’s IgG in the first si=x month
it will only contain the mothers IgG
what is the first isotype produced by the immune system
IgM
what is used to determine whether an infection is acute or chronic
IgM
IgM forms a ______
pentameter
what antibodies are bound by J chain
IgM and IgA
secreted IgA forms _____
dimer
what is the function of pIgR
bind to J chain and transcytose Ig through the epethelial cell to the apical side
when antibodies bind to NA or HA portions until particle is opsonized
neutralization
what antibody causes degranulation
IgE
what is complement-dependent cell cytotoxicity and what antibodies are involved
classical complement pathway; IgM (best) and IgG
antibody dependent cell cytotoxicity involes
NK cells and binding to Fc(gamma)R
the spleen plays and important role in
- site of natural antibody production
- added source of IgG serum
- site of blood filtering phagocytes
what provides specificity for NK cells
IgG
what antibodies are involved in neutralization
IgA, IgM, IgG
what antibody is involved in complement activation
IgM
what antibody is involved in opsonization
IgG
mast cells are activated by
IgE
