Gamma Glutamyl Transferase (GGT) Flashcards
catalyze the transfer of y-glutamyl residue from y-glutamyl peptide to amino acid, H2O
GGT
most common donor of gamma-glutamyl peptide
Glutathione
GGT is sensitive marker for the detection
Ethanol Detoxification
GGT marker for diagnosis of
HEPATOBILIARY disorder
Chronic Alcoholism
Occult Alcoholism
GGT Enzymatic Reaction
Glutathione + amino acid —> glutamyl-peptide + L-cysteinylglycine
Assay for Enzyme Activity of GGT
Szaz Assay
Absorbance of ______ is measured in GGT
P-nitroaniline
Absorbance is measured within
405-420 nm
Szaz Assay Reaction
Y-glutamyl-p-nitroanilide + glycylglycine —> y-glutamyl-glycylglycine + p-nitroaniline
Required coenzyme for Szaz Assay
Aminotransferase
coenzyme for the activity of aminotransferase
Pyridoxal Phosphate (Vit B6)