Gall stones Flashcards
What is cholelithiasis
Prescence of gall stones
What is choledocholthiasis
Presence of gall stones in common bile duct
How do gall stones form
Imbalance between ratio of cholesterol and bile pigments in bile
Too much cholesterol - age, obesity
Too much bilirubin - haemolysis
Not enough bile salts
What is cholesterolsis
Increased cholesterol in gall bladder forming HB polyps
What are the symptoms of gall stone
Asymptomatic (30%)
Dyspepsia
Loss of appetite
Biliary colic if stone gets stuck in CBD (RUQ pain radiating to back +- jaundice + N+V)
Colic last longer than obstruction
Sympyoms when stuck in CBD Jaundice Dark urine Pale stool Pruritus Steattorhea
Exam
- Scars as laparoscopic
- HSM or palpable GP - suggest malignancy
- Murphy’s for cholecystitis
What suggests abscess
Hx RUQ pain
Swinging fever
What are the RF for gall stones
Age Female OCP Obesity DM Pregnancy Hyperlipidaemia Haemolytic anaemia Bile infection Low fibre, high fat Rapid weight loss FH IBD - terminal ileal as affects absorption of bile salt
What are the complications of gallstones
If in bile duct
- Obstructive jaundice
- Cholangitis (bile duct)
- Pancreatitis as enzymes back up
- Cirrhosis
Gall bladder / cystic duct
- Biliary colic
- Cholecystits
- Empyema
- Obstruction
- Mirizzis syndrome
- Gall stone ileus
Empyema / abscess = emergency
Peritonitis
What is Mirizzi
Gall stone in GB compresses CBD
What is gall stone ileus
Fistula between gall bladder and duodenum
Stone passes and obstructs
What are the Sx of gall stone ileus
HX gall stone
Abdominal pain
Distension
Vomit
How do you Dx gall stone ileus
Laparotomy
What are cholendochal cysts
Remove as can be cancerous
How do you Dx gall stone
What other investigations for Ddx
Blood -FBC, U+E, LFT, CRP, amylase
USS = 1st line
Standard workup
Do urinalysis, CXR and ECG for DDX
What should you always do in renal / biliary colic in men
CT KUB
Assume AAA until proven otherwise
What are signs suggesting AAA
Pulsatile and expnasile mass
Do aorta exam on every abdominal
What should you do if suspect stone in CBD
MRCP
ERCP if going to remove
Not urgent if no cholangitis
Likely to cholecystectomy after
What will stones in CBD or hepatic duct cause
Jaundice
If in cystic or gall bladder = no jaundice
How do you treat asymptomatic gall stones
Observe
What do you do if symptomatic / risk of complications
Rehydrate
NBM
Laparoscopic cholecystectomy = gold standard to remove gall bladder
What is often found at cholecystectomy
Stones in CBD
Can remove at operation or early ERCP in days following
What suggest stone in CBD
Ongoing RUQ pain / jaundice
What are other options if unfit
ORSO dissolution
UDCA