GA agents Flashcards
What are features of propofol?
Rapid onset of anaesthesia
Pain on IV injection
Rapidly metabolised with little accumulation of metabolites
Proven anti emetic properties
Moderate myocardial depression
Widely used especially for maintaining sedation on ITU, total IV anaesthesia and for daycase surgery
What are features of sodium thiopentone?
Extremely rapid onset of action making it the agent of choice for rapid sequence of induction
Marked myocardial depression may occur
Metabolites build up quickly
Unsuitable for maintenance infusion
Little analgesic effects
What are features of ketamine?
May be used for induction of anaesthesia
Has moderate to strong analgesic properties
Produces little myocardial depression making it a suitable agent for anaesthesia in those who are haemodynamically unstable
May induce state of dissociative anaesthesia resulting in nightmares
What are features of etomidate?
Has favorable cardiac safety profile with very little haemodynamic instability
No analgesic properties
Unsuitable for maintaining sedation as prolonged (and even brief) use may result in adrenal suppression
Post operative vomiting is common
Which GA has anti-emetic properties?
Propofol
Which GA is suitable for rapid anaesthesia for haemodynamic unstable patients?
Ketamine
Which GA can result in adrenal suppression?
Etomidate
Which GA can cause myocardial depression?
Sodium thiopentone
Which GA can result in dissociative anaesthesia?
Ketamine
Which GA is not suitable for maintaining sedation?
Etomidate
Sodium thiopentone
Which GA has little analgesic effect?
Sodium thiopentone
Which GA can cause post-op vomiting?
Etomidate
