FUNCTIONAL ANATOMY - Hearing, Olfaction and Taste Flashcards

1
Q

What are the two properties of sound?

A

Frequency
Amplitude

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2
Q

Describe how sound is transmitted down the external and middle ear and into the inner ear

A

Sound waves enter the auricle and are transmitted down the external acoustic meatus to the tympanic membrane. The tympanic membrane vibrates and transmits these vibrations through the ossicles which vibrate the vestibular (oval) window into the inner ear

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3
Q

What is the function of the organ of corti?

A

The organ of corti which converts sound vibrations into neural impulses which can be transmitted to the brain

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4
Q

Describe the structure of the organ of corti

A

The organ of corti consists of hair cells innervated by the cochlear branch of cranial nerve VIII and fixed to the basilar membrane

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5
Q

Describe how sound waves are converted to neural impulses by the organ of corti

A

Vibration of the stapes against the vestibular (oval) window creates pressure waves which move through the fluid within the scala vestibuli, cochlear duct and the scala tympani to the cochlear (round) window where the pressure will be dissipated into the middle ear. As the pressure waves travel through the cochlear duct, the basilar membrane is displaced leading to displacement of the sterocilia of the hair cells and transmission of action potentials down the cochlear branch of cranial nerve VIII

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6
Q

What is the difference between inner and outer hair cells?

A

Inner hair cells convert sound waves into neural impulses whereas outer hair cells amplify and fine-tune sounds through altering the tension of the basilar membrane

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7
Q

How does the basilar membrane exhibit topographical organisation?

A

Different regions of the basilar membrane are sensitive to different frequencies of sound. The base of the basilar membrane is sensitive to high frequency so higher frequency sounds are going to deflect the basilar membrane closer to the vestibular (oval) window whereas the apex of the basilar membrane is sensitive to low frequency so lower frequencies are going to deflect the basilar membrane further from the vestibular (oval) window

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8
Q

How do the cochlear neurones of cranial nerve VIII exhibit tuning curves?

A

Each cochlear neurone of cranial nerve VIII exhibits a tuning curve which shows the range of frequency that specific neurone can detect and respond to, with each neurone having an optimal frequency

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9
Q

How does an increase in amplitude (dB) influence frequency?

A

An increase in amplitude (dB)/sound intensity results in a wider range of frequencies in which cochlear neurones can respond to

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10
Q

Describe the auditory pathway

A

Neural impulses are transmitted along the cochlear neurones of cranial nerve VIII to the cochlear nucleus in the brain stem. Information is then transmitted to the superior olivary nucleus in the brainstem, followed by the caudal colliculus in the midbrain, to the medial geniculate nucleus in the thalamus and finally to the auditory cortex

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11
Q

What is the key function of the superior olivary nucleus in the auditory pathway?

A

Processing and integration of sound arrival time and intensity in both ears to localise the direction of a sound source

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12
Q

What are the two divisions of the superior olivary nucleus?

A

Lateral superior olive
Medial superior olive

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13
Q

What is the function of the lateral superior olive?

A

Processing and integration of sound intensity

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14
Q

What is the function of the medial superior olive?

A

Processing and integration of sound arrival time

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15
Q

What is conduction deafness?

A

Disorders of the external and middle ear causing hearing impairment/loss

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16
Q

What are two external ear disorders which can cause conduction deafness?

A

Cerumen (excessive ear wax)
Otitis externa

17
Q

Which middle ear disorder can cause conduction deafness?

A

Fluid accumulation in the auditory tube

18
Q

What is sensorineural deafness?

A

Lesions of the cochlea or cranial nerve VIII causing hearing impairment/loss

19
Q

What is a common clinical sign of hair cell damage?

A

Tinnitus

20
Q

What can be used to treat sensorineural deafness caused by hair cell loss?

A

Cochlear implant

21
Q

What is central deafness?

A

Brain lesions which causing hearing impairment/loss

22
Q

How is the olfactory system significantly different to other sensory modalities?

A

The olfactory system doesn’t involve the thalamus like all of the other sensory modalities

23
Q

What is the purpose of the bowman’s glands within the olfactory epithelium?

A

Bowman’s gland produce mucous

24
Q

Why do odorants have to be partially lipid soluble?

A

Odorants have to be partially lipid soluble to penetrate the mucous to reach the underlying olfactory receptors

25
Q

What happens when odorants bind to olfactory receptors?

A

The binding of odorants to olfactory receptors stimulate intracellular pathways, triggering action potentials along cranial nerve I (olfactory nerve)

26
Q

Describe the olfactory pathway

A

Nerve impulses are transmitted along cranial nerve I (olfactory nerve) to the olfactory bulb which contains mitral cells which transmit olfactory information via the olfactory tract to the limbic system

27
Q

What are the functions of the vomeronasal organ?

A

Pheromone detection

28
Q

How does the olfactory pathway differ for the vomeronasal organ?

A

For the vomeronasal organ, nerve impulses are transmitted along cranial nerve I (olfactory nerve) to the accessory olfactory bulb which contains mitral cells which transmit olfactory information specifically to the amygdala of the limbic system

29
Q

(T/F) The olfactory system shows complete adaptation

A

TRUE.

30
Q

Where are taste receptors located within the tongue?

A

Taste receptors are located within buds within papillae