Frog Quiz Flashcards
The gray crescent is necessary to form ___. Without it, you form ___.
Gray crescent is necessary to form axial structures. Otherwise you get the belly piece, chicken mcnuggets.
What happens with MTs over expressed?
Axial head structures overexpressed
What factors are involved in expressing B catenin in excess?
Presence of disheveled, GSK-3, and Wnt 11
What does B catenin cause transcription of?
Siamois, and Twin
Mesoderm Induction: Step 1
Vg1 (TGF Beta protein) induces VegT (transcription factor) which causes endoderm formation, increased Beta catenin increases nodal.
Mesoderm Induction: Step 2
Graded Nodal expression dorsal/ventral
Mesoderm Induction: Step 3
Mesoderm induced in the marginal zone from underlying vegetal cells
Ventral Dorsal Interaction: BMPs
Ventral BMPs inhibited by Dorsal Noggin and Chordin
Ventral Dorsal Interaction: XWnt8
Ventral XWnt8 inhibited by Dorsal FrzB,Dickkopf, and Cerberus
Without ventral signals, ectoderm will become ___
Neural
Neural Induction: What posteriorizes?
Wnt, FGF, RA
Neural Induction: What creates the spinal cord?
BMP inhibitors
Neural Induction: What creates brain?
Wnt inhibitors
NIMZ after gastrulation
part becomes neural ectoderm, part becomes epidermis
IMZ after gastrulation Dorsal Deep Cells & Dorsal Superficial Cells
Dorsal Deep Cells: Organizer
Dorsal Superficial Cells: Roof of archenteron, endoderm