Food Allergies

Question 1

TH1 vs TH2

Answer 1

antagonistic relationship
absolute levels lead to allergy (if alot more one vs other
1=virus, bacteria, protozoa
2=parasites

Question 2

Gliadin

• structure
• does what

Answer 2

proline and glutamine rich

Bind to DQ2 antigen
-activated by tissue glutaminase=crosslinnk=stronger autoimmune reactio

Question 3

pre vs pro biotics

Answer 3

pre feeds biota

post is biota

Question 4

Clostridium bacteria

Answer 4

from maternal gut, to breast milk to baby (all microbiota to baby like this)
=expansion of Treg cells
=class swtich to IgA (from IgE i think)
—–doesnt let stuff through epithlium

Question 5

Increased bacteria=

Answer 5

less alergic respoinse

-

Question 6

Breast milk has

Answer 6

several lactic acid baceteria (clostrida)

Milk oligosacs

Question 7

Milk oliggo sacs

Answer 7

noursh good bacteria

prevent grwoth of harmful bacteria

Question 8

Undertstimulation of TH1=high TH2 levels

Answer 8

@ farm-less expansion of other childrens infections

Question 9

Food adjuctives

• types
• what do

Answer 9

sultites, nitrtites, nitrates, MSG

stim immune response-can lead to allergic rxn

Question 10

SLIT

Answer 10

small amounts given under tongue
-IgG levels rise drastically=bind to allergen before IgE can

stimulation of Treg levels

Question 11

Anti IgE/receptor therapy

Answer 11

block FCepsilonRecptor of mast cell
block IgE-R

or change molecule so cant bind to these areas )allsteric binding to TgE can dissocatie IgE from recepotor