Fluid, Electrolyte, and Acid-Base Balance Flashcards
Fluid:
water that contains dissolved or suspended substances such as glucose, mineral salts, and proteins
ECF:
Extracellular fluid: outside the cells
ICF:
Intacellular fluid: inside the cells
ECF has 2 major divisions, and 1 minor division:
Major:
1. Intravascular fluid: liquid portion of blood
2. Interstitial fluid: between cells and outside blood vessels
Minor:
1. Transcellular fluids: secreted by epithelial cells-cerebrospinal, pleural, peritoneal, and synovial fluids
ECF Contains
Sodium, chloride, and bicarbonate
Albumin (intravas)
Gastric and intestinal secretions (trans)
ICF Cations and Anions:
C: Potassium and magnesium
A: phosphate
Osmolality of a fluid is a
measure of particles per kilogram of water
Normal value range for Osmolality:
280-300 mOsm/kg H2O
Normal range for Sodium:
136-145 mEq/L
Normal range for Potassium:
3.5-5.0 mEq/L
Normal range for Chloride:
98-106 mEq/L
Normal range for Bicarbonate (HCO3):
22-26 mEq/L
Normal range for calcium:
8.5-10 mg/dL
Normal range for magnesium:
1.5-2.5 mEq/L
Normal range for Anion gap:
5-11 mEq/L
Normal range for pH:
7.35-7.45
Normal range for PaCO2 (Arterial blood gases):
35-45 mm Hg
Normal range for Arterial blood gases PaO2:
80-100 mm Hg
Normal range for Arterial blood gases O2 Sat:
95-100%
Brain Natriuretic peptide:
determine presence of heart failure with fluid excess
Evaluation for patients who have congestive heart failure 0-100
Isotonic:
Use 5% dextrose in water
fluid with the same concentration of nonpermeant particles as normal blood
Hypotonic:
45% normal solution
more dilute than the blood
Hypertonic:
5% dextrose in normal saline, 10% dextrose in water, lactated ringers
more concentrated than normal blood
Active transport:
cells maintain their high intracellular electrolyte concentration
ATP moves electrolytes across cell membranes against the concentration gradient
Ex. Sodium potassium pump: Na out and K in
Osmosis:
Water moves through membrane that separates fluid with different particle concentrations –> meet equilibrium
osmotic pressure: inward pulling force caused by particles in the fluid
Filtration:
fluid moves into and out of capillaries
Hydrostatic pressure: the force of the fluid pressing outward against a surface
Colloids: containing albumin and other proteins
Colloid osmotic pressure or oncotic pressure: inward pulling force caused by blood proteins that help move fluid from interstitial area back into capillaries
Diffusion:
passive movement of electrolytes or other particles down the concentration gradient (high areas to low)
Normal range for Fluid Intake:
Women: 2700 ml/day
Men: 3500 ml/day
Normal range for Output:
Urine 1500 ml/day
Defecation 100-200 ml/day
Fluid output normally occurs through 4 organs:
Skin
Lungs
GI tract
Kidneys
Abnormal fluid includes:
Vomiting
Wound drainage
Hemorrhage
ADH:
Vasopressin
water retainer, increasing water retention
regulates the osmolality of the body fluids by influencing how much water is excreted in urine
Renal failure will not be able to absorb or secrete this hormone
More ADH is released if body fluids become more concentrated
RAAS:
Converts Angiotensis 1 to 2, stimulates production of aldosterone = increases BP
High BP = ACE inhibitor
Angiotensin
Converting
Enzyme
Aldosterone:
Passive, water absorbed and blood volume expands
Maintains BP and fluid balance
Thyroid:
cardiac output increased glomerular excretion rate, filter faster more urine
Extracellular fluid volume imbalances:
- ECV deficit: present when there is insufficient isotonic fluid in the extracellular compartment
- Hypovolemia: decreased vascular volume, often used when discussing ECV deficit
- ECV excess: there is too much isotonic fluid in the extracellular compartment, intake of sodium containing isotonic fluid has exceeded fluid output
Osmolality imbalances:
Hypernatremia: water deficit, hypertonic condition,
2 causes: loss of relatively more water than salt
gain of relatively more salt than water
Hyponatremia: water excess or water intoxication, hypotonic condition, arises from gain of relatively more water than salt or loss of relatively more salt than water
Clinical dehydration:
the combination of ECV deficit and hypernatrmia occur at same time
Where can you find Potassium?
Fruits Potatoes Instant coffee Molasses Brazil nuts Absorbs easily
Where can you find calcium?
dairy products canned fish with bones broccoli oranges requires vitamin D for best absorption undigested fat prevents absorption
Where can you find Magnesium?
dark green leafy vegetables
whole grains
Mg containing laxatives and antacids
Undigested fat prevents absorption
Where can you find phosphate?
Milk
processed foods
Aluminum antacids prevents absorption
What are used to monitor a patient’s acid base balance?
lab tests of blood called ABGs Arterial blood gases
-Also reveals adequacy of ventilation and oxygention
Acid production: 2 types
Cellular metabolism creates
- Carbonic acid: H2CO3
- Metabolic acids: any acids are not carbonic acid which include citric acid, lactic acid