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First Aid: pscyhopharmacology Flashcards

1
Q

first-line treatment for extrapyramidal symtpoms caused by antipsychotics

A

Benztropine

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2
Q

tardive dyskinesia

A

grimacing and tongue protrusion

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3
Q

acute dystonia

A

intermittent spasmodic or sustained involuntary contractions of muscles in the face, neck, trunk, pelvis, extremities, and even the larynx.

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4
Q

Akathisia

A

restlessness

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5
Q

bradykinesia

A

slow body movement

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6
Q

common side effect of anticholinergic medication

A

constipation

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7
Q

Anticholinergic medications exacerbate what disorders

A

neurocoginitive (dementias)

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8
Q

HAM side effects

A
  1. antihistamine: sedation, weight gain
  2. antiadrenergic: hypotension
  3. antimuscurinic: dry mouth, blurred vision
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9
Q

which drugs have HAM side affects

A
  1. TCAs

2. low-potency antipsychotics

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10
Q

drugs that cause serotonin syndrome

A

SSR

MOAI

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11
Q

What is hypertensive crisis

A

buildup of stored catecholamines

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12
Q

what causes hyperprolactinemia

A
  1. high potency typical antipsychotics

2. risperidone

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13
Q

CYP450 inducers

A
  • tobacco
  • carbamazepine
  • barbituates
  • St. John wort
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14
Q

CYP450 inhibitors

A
  • FLuvoxamine
  • Fluoxetine
  • Paroxetine
  • Duloxetine
  • Sertaline
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15
Q

CYP450 inhibitors do what to drugs

A

increase drug levels

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16
Q

CYP450 inducers do what to drugs

A

decrease drug levels

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17
Q

What percent of patients respond to anti-depressants

A

60-70

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18
Q

Longest half life SSRI

A

Fluoxetine

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19
Q

SSRI with highest GI upset

A

Sertaline

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20
Q

which SSRI is the only drug approved for OCD

A

Fluvoxamine

21
Q

Black box warning for SSRI drugs

A

suicidal thinking and behavior in children and young adults

22
Q

Side effect of SNRI

A

increase blood pressure

23
Q

why would you perscribe Bupropion over SSRI

A

lack of sexual side effects

24
Q

Black box warning for Nafezodone

A

serious liver failure

25
Q

what is prescribed to elderly patients for treating major depression and helps with sleep and appetite

A

Mirtazapine

26
Q

TCA used to treat OCD

A

Clomipramine

27
Q

TCA used to treat enuresis

A

Imipramine

28
Q

treatment for overdose TCA

A

sodium bicarbonate

29
Q

3 C side effects of TCA

A

Cardiotoxicity
Convulsoins
Coma

30
Q

Depression with atypical features, characterized by hypersomnia, increased appetite, leaden paralysis, and increase sensitivity to inerpersonal rejection. Treatment?

31
Q

MOA for MAOI

A

irreversibly inhibits enzymes MAO-A and B

32
Q

treatment for serotonin syndrome

A
  1. discontinue medication
  2. Benzo and supportive care
  3. cyproheptadine
33
Q

warning with atypical antipsychotics for elderly

A

all-cause mortality and stroke

34
Q

side effect profile for low potency typical antipsychotics

A

antiadrenergic
anticholinergic
antihistaminic

35
Q

how is high-potency antipyschotics given to the patient? which ones

A

intramuscular

  • haloperidol
  • fluphenazine
36
Q

what dopamine pathway is blocked for treatment of positive symtpoms

A

mesolimbic

37
Q

what causes negative symptoms of schizophrenia

A

mesocortical

38
Q

what causes extrapyramidal symptoms

A

nigrostiatum

39
Q

treatment for akathisia

A

beta blockers and benzos

40
Q

dystonia

A

sustained painful contraction of muscles

41
Q

who is at an increased risk for getting tardive dyskinesia

A

women and patients with affective disroders

42
Q

Which antipsychotic is shown to decrease risk of suicide

43
Q

Lurasidone treats

A

bipolar depression

44
Q

Therapuetic range for lithium

45
Q

Anticonvulsants are good at treating

A

mixed features and rapid-cycling bipolar disorders

46
Q

main side effects of carbamazapine

A

Stevens-Johnson syndrome

Teratogenic: neural tube defects

47
Q

Use for lamotrigine

A

bipolar depression

48
Q

side effect of Lamotrigine

A

stevens-johnson syndrome

49
Q

Side effect of topiramate

A

weight loss

cognitive slowing

Psychology (21 decks)

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