First Aid: pscyhopharmacology Flashcards
first-line treatment for extrapyramidal symtpoms caused by antipsychotics
Benztropine
tardive dyskinesia
grimacing and tongue protrusion
acute dystonia
intermittent spasmodic or sustained involuntary contractions of muscles in the face, neck, trunk, pelvis, extremities, and even the larynx.
Akathisia
restlessness
bradykinesia
slow body movement
common side effect of anticholinergic medication
constipation
Anticholinergic medications exacerbate what disorders
neurocoginitive (dementias)
HAM side effects
- antihistamine: sedation, weight gain
- antiadrenergic: hypotension
- antimuscurinic: dry mouth, blurred vision
which drugs have HAM side affects
- TCAs
2. low-potency antipsychotics
drugs that cause serotonin syndrome
SSR
MOAI
What is hypertensive crisis
buildup of stored catecholamines
what causes hyperprolactinemia
- high potency typical antipsychotics
2. risperidone
CYP450 inducers
- tobacco
- carbamazepine
- barbituates
- St. John wort
CYP450 inhibitors
- FLuvoxamine
- Fluoxetine
- Paroxetine
- Duloxetine
- Sertaline
CYP450 inhibitors do what to drugs
increase drug levels
CYP450 inducers do what to drugs
decrease drug levels
What percent of patients respond to anti-depressants
60-70
Longest half life SSRI
Fluoxetine
SSRI with highest GI upset
Sertaline