final Flashcards
Introduction to The Muscular System
Skeletal muscles: movement in environment•Smooth muscles: intestines, ureters, veins and arteries•Cardiac muscle: pumps blood through heart and blood vessels•40–50% of body weight
The Types of Muscle
- Skeletal
- Smooth
- Cardiac
Skeletal
Skeletal: voluntary, striated, and multinucleated
Smooth
Smooth: involuntary, nonstriated, and uninucleated
Cardiac
Cardiac: involuntary, striated, and uninucleated
The Anatomy of Skeletal or Striated Muscle
- Skeletal muscle cell surrounded by sarcolemma
- Fasciculi: bundles of fascicles
- Fascicles: individual bundles of muscle fibers
- Perimysium: surrounds each fascicle
- Epimysium: covers the perimysium
- Fascia: covers the epimysium•Myosin: A bands
- Actin: I bands
- Z lines
- H zone
- Sarcomere: between two adjacent Z lines–Actual contraction process occurs here
- Sarcotubular system–T system and sarcoplasmic reticulum
Introduction to The Physiology of Muscle Contraction
- Motor unit: all muscle cells innervated by one motor neuron
- Muscle cell properties–Excitability–Conductivity–Contractility–Elasticity
The Physiology of Muscle Contraction: Neuroelectrical Factors
•Na+ higher concentration outside muscle cell
•K+ higher concentration inside muscle cell
•Resting potential: charge outside positive and inside negative
•Electrical potential: rush of Na+ inside cell
•K+ moves outside cell attempting to balance
•Action potential
–Calcium released
–Troponin and tropomyosin action inhibited
–Activated myosin links to actin filaments
The Physiology of Muscle Contraction: Chemical Interactions
- Myosin heads contain ATP
- ATP releases energy upon myosin/action link
- Energy released used to pull action
- Sodium: potassium pump pumps out sodium
- Resting potential restored
The Physiology of Muscle Contraction: Energy Sources
•ATP: energy source for muscle contraction
•ATP production
–Glycolysis
–Krebs citric acid cycle
–Electron transport
•Alternate sources: fatty acids and phosphocreatine
The Muscle Twitch
•Stimulus > latent period > contraction > relaxation
•Contraction strength depends on
–Strength, speed, and duration of stimulus
–Weight of load
–Temperature
•All-or-none law
Muscle Tone
•State of partial contraction throughout whole muscle
•Maintains pressure on abdominal contents
•Helps maintain blood pressure
•Aids digestion
•Types
–Isotonic, isometric
The Anatomy of Smooth Muscle
•Found in hollow structures •Involuntary, uninucleated, nonstriated •Arrangement (two layers) –Longitudinal (outer) –Circular (inner)
The Anatomy of Cardiac Muscle
- Autonomic nervous system control
- Involuntary, uninucleated, striated
- Intercalated disks: coordinate contraction
- Cardiac muscles: contract, relax, and contract 75 times/minute
The Naming and Actions of Skeletal Muscles
- Action
- Shape
- Origin and insertion
- Location
- Direction of fibers
- Origin: more fixed attachment of muscle
- Insertion: movable attachment of muscle
- Tendons: attach muscle to bone
- Aponeurosis: wide flat tendon
- Flexors: bend limb at a joint
- Extensor: straighten limb at a joint
- Abductors: move limb away from midline
- Adductors: bring limb toward midline
- Rotators: revolve limb around axis
- Dorsiflexors: raise the foot
- Plantar flexors: lower the foot
- Supinators: turn palm upward
- Pronators: turn palm downward
- Levators: raise a part of the body
- Depressors: lower a part of the body
- Prime movers or agonists: bring about an action
- Antagonists: oppose agonists
- Synergists: assist prime movers
Origin
Origin: more fixed attachment of muscle
Insertion
Insertion: movable attachment of muscle
Tendons
Tendons: attach muscle to bone
Aponeurosis:
Aponeurosis: wide flat tendon
Flexors
Flexors: bend limb at a joint
Extensor
Extensor: straighten limb at a joint
Abductors
Abductors: move limb away from midline
Adductors
Adductors: bring limb toward midline
Rotators
Rotators: revolve limb around axis
Dorsiflexors
Dorsiflexors: raise the foot
Plantar flexors:
Plantar flexors: lower the foot
Supinators
Supinators: turn palm upward
Pronators
Pronators: turn palm downward
Levators
•Levators: raise a part of the body
Depressors
Depressors: lower a part of the body
Prime movers or agonists
Prime movers or agonists: bring about an action
Antagonists
Antagonists: oppose agonists
Synergists
Synergists: assist prime movers
The Function and Location of Selected Skeletal Muscles: Superficial Muscles
Superficial muscles of the body, anterior view
Superficial muscles of the body, posterior view
Muscles of Facial Expression
- Occipitalis
- Frontalis
- Zygomaticus
- Levator labii superioris
- Orbicularis oris and buccinator
Muscles of Mastication
- Masseter
- Temporalis
- Pterygoid
Muscles of the Eye
- Superior rectus•Inferior rectus
- Medial rectus•Lateral rectus
- Superior and inferior oblique
Muscles Moving the Head
Sternocleidomastoid
–Contraction of both causes flexion of neck
–Contraction of one causes rotation to left or right
Muscles Moving the Shoulder Girdle
- Levator scapulae
- Rhomboids
- Pectoralis minor
- Trapezius
- Serratus anterior
Muscles Moving the Humerus
- Pectoralis major
- Latissimus dorsi
- Teres minor
- Deltoid
- Supraspinatus
- Infraspinatus
Muscles Moving the Elbow
- Brachialis
- Biceps brachii
- Brachioradialis
- Triceps brachii
- Anconeus
Muscles Moving the Wrist
- Flexor carpi
* Extensor carpi
Muscles Moving the Hand
- Supinator
- Pronator teres
- Pronator quadratus
Muscles Moving the Thumb
- Flexor pollicis
- Extensor pollicis
- Adductor pollicis
- Abductor pollicis
- Opponens pollicis
Muscles Moving the Fingers
- Flexor digitorum
- Extensor digitorum
- Interossei
Muscles of the Abdominal Wall
- External oblique
- Internal oblique
- Transversus abdominis
- Rectus abdominis
Muscles of Respiration or Breathing
•Diaphragm
–Main muscle
•External and internal intercostals
–Expand the ribs
Muscles Moving the Femur
- Psoas
- Iliacus
- Gluteus maximus
- Gluteus medius
- Gluteus minimus
- Tensor fascia lata
Muscles Moving the Knee Joint
- Biceps femoris
- Semitendinosus
- Semimembranosus
- Popliteus
- Gracilis
- Sartorius
- Quadriceps femoris
Muscles Moving the Foot
- Gastrocnemius
- Tibialis posterior
- Soleus
- Peroneus longus
- Plantaris
- Tibialis anterior
- Peroneus tertius
Muscles Moving the Toes
- Flexor hallucis
- Extensor hallucis
- Flexor digitorum
- Extensor digitorum
- Abductor hallucis
- Abductor digiti minimi
The Nervous SystemIntroduction, Spinal Cord, and Spinal Nerves Introduction
•Control center and communication network
–Directs functions of body’s organs and systems
–Interprets external environment
–Determines reaction to change
•Homeostasis: balanced internal environment–Controlled by nervous and endocrine systems
Homeostasis
Homeostasis: balanced internal environment–Controlled by nervous and endocrine systems
Organization
•Central nervous system: brain and spinal cord
•Peripheral nervous system
–Afferent peripheral system
•Sensory neurons
–Efferent peripheral system
•Somatic
•Autonomic: sympathetic and parasympathetic
•Central nervous system
•Central nervous system: brain and spinal cord
•Peripheral nervous system
•Peripheral nervous system
–Afferent peripheral system
•Sensory neurons
•Sensory neurons
–Efferent peripheral system
Neuroglia Cells
- Astrocytes: support, connection, blood-brain barrier
- Oligodendroglia: support, myelin sheath formation
- Microglial: phagocytosis
- Ependymal: line the ventricles of the brain
- Schwann: myelin sheaths in peripheral nervous system
Astrocytes
•Astrocytes: support, connection, blood-brain barrier
Oligodendroglia
•Oligodendroglia: support, myelin sheath formation
Microglial
Microglial: phagocytosis
Ependymal
•Ependymal: line the ventricles of the brain
Schwann
Schwann: myelin sheaths in peripheral nervous system
The Structure of a Neuron
•Cell body
•Dendrites: receptive areas
•Axon: extension of cell body
–Schwann cells
–Nodes of Ranvier
•Multipolar: several dendrites coming off cell body
•Bipolar: one dendrite and one axon
•Unipolar: one process extending from cell body
•Receptors: detect environmental stimuli
•Sensory: receive impulse from receptor site
•Internuncial: transmit impulse for interpretation and processing
•Motor: reaction to the stimulus
•Dendrites
•Dendrites: receptive areas
Axon
•Axon: extension of cell body
–Schwann cells
–Nodes of Ranvier
Multipolar
Multipolar: several dendrites coming off cell body
Bipolar
Bipolar: one dendrite and one axon
Unipolar:
Unipolar: one process extending from cell body
Receptors
Receptors: detect environmental stimuli
Sensory
Sensory: receive impulse from receptor site
Internuncial
•Internuncial: transmit impulse for interpretation and processing
Motor
•Motor: reaction to the stimulus
The Physiology of the Nerve Impulse
•Nerve cell fiber resting potential –Na+ concentration higher on outside –K+ concentration higher on inside –Negative charge on inside –Positive charge on outside •Depolarization: Na+ rush inside cell •Repolarization: K+ rush out to restore balance •Depolarization: Repolarization moves in one direction •Myelinated vs. unmyelinated •All-or-none law
The Synaptic Transmission
•Synapse: axon terminal branches close to next dendrites •Impulse reaches axon terminals •Triggers neurotransmitter release into synaptic cleft •Neurotransmitters –Acetylcholine •Most common –Epinephrine –Norepinephrine –Serotonin –Dopamine –Endorphins
The Reflex Arc
•Knee-jerk reflex •Maintain homeostasis –Heartbeat/breathing rates –Digestion –Coughing –Sneezing –Swallowing –Vomiting
Grouping of Neural Tissue
•White matter –Groups of myelinated axons –Forms nerve tracts in CNS •Gray matter –Nerve cell bodies and dendrites –Unmyelinated axon bundles –Cortex: gray matter on surface of brain
Grouping of Neural Tissue
•White matter –Groups of myelinated axons –Forms nerve tracts in CNS •Gray matter –Nerve cell bodies and dendrites –Unmyelinated axon bundles –Cortex: gray matter on surface of brain •Nerve: bundle of fibers outside CNS •Ganglia: nerve cell bodies outside CNS •Tract: bundle of fibers inside CNS •Nucleus: nerve cell bodies and dendrites inside CNS •Horns: areas of gray matter in spinal cord
White matter
•White matter
–Groups of myelinated axons
–Forms nerve tracts in CNS
Gray matter
•Gray matter
–Nerve cell bodies and dendrites
–Unmyelinated axon bundles
–Cortex: gray matter on surface of brain
Nerve
•Nerve: bundle of fibers outside CNS
Ganglia
•Ganglia: nerve cell bodies outside CNS
Tract
•Tract: bundle of fibers inside CNS
Nucleus
•Nucleus: nerve cell bodies and dendrites inside CNS
Horns
•Horns: areas of gray matter in spinal cord
The Spinal Cord Introduction
•Continuation of medulla oblongata •31 segments each with a pair of spinal nerves •Protected by meninges –Dura mater –Arachnoid –Pia mater
Functions of the Spinal Cord
•Conveys sensory impulses to the brain •Integrates reflexes •Spinal nerves connect at roots –Dorsal root: sensory –Ventral root: motor
The Spinal Nerves
•All 31 pairs arise from union of dorsal and ventral roots
•Mixed nerves consisting of motor and sensory fibers
•Most exit vertebral column between vertebrae
•Named and numbered according to region and level of spinal cord
–Cervical: 8 pairs
–Thoracic: 12 pairs
–Lumbar: 5 pairs
–Sacral: 5 pairs
–Coccygeal: 1 pair
The Nervous SystemThe Brain, Cranial Nerves, Autonomic Nervous System, and the Special Senses Introduction
•Brain is divided into four main parts
–Brainstem: controls breathing, heartbeat rates and reactions to auditory and visual stimuli
–Diencephalon: controls homeostasis
–Cerebrum: controls intellectual processes and emotions
–Cerebellum: maintains body posture and balance
Brainstem
–Brainstem: controls breathing, heartbeat rates and reactions to auditory and visual stimuli
Diencephalon
–Diencephalon: controls homeostasis
Cerebrum
–Cerebrum: controls intellectual processes and emotions
Cerebellum
–Cerebellum: maintains body posture and balance
•Brain is divided into four main parts
–Brainstem:
–Diencephalon:
–Cerebrum:
–Cerebellum:
The Principal Parts of the Brain
•Main parts: brainstem, diencephalon, cerebrum, and cerebellum •Protection –Cranial bones –Meninges –Cerebrospinal fluid •Ventricles –Interventricular foramen
•Main parts of the brain
•Main parts:
- brainstem,
- diencephalon,
- cerebrum,
- and cerebellum
Protection for the brain
Protection
–Cranial bones
–Meninges
–Cerebrospinal fluid
Ventricles of the brain
Interventricular foramen
The Anatomy and Functions of the Brainstem
- Medulla oblongata
- Pons varolii
- Midbrain
Medulla oblongata
•Medulla oblongata –Ascending and descending tracts –Connect spinal cord with the brain –Some tracts cross over in medulla –Reticular formation: controls consciousness –Reflex centers
•Pons varolii
•Pons varolii
–Connects spinal cord with brain
–Connects parts of brain with each other
–Helps control breathing
•Midbrain
•Midbrain
–Ventral cerebral peduncles: convey impulses from cortex to pons and spinal cord
–Dorsal tectum: reflex center
–Controls movement of head and eyeball (visual stimuli)
–Controls movement of head and trunk (auditory stimuli)
The Anatomy and Functions of the Diencephalon
•Optic tracts
•Mamillary bodies: memory and emotional responses
•Thalamus
–Relay station for sensory impulses
–Interpretation center for pain, temperature, and touch
•Epithalamus: contains pineal gland
•Hypothalamus: homeostasis
–Controls and integrates autonomic nervous system
–Receives sensory impulses from internal organs
–Controls pituitary gland and links endocrine and nervous systems
The Cerebrum: Structure and Function
•Cerebral cortex: gray matter surface
•Longitudinal fissure separates two hemispheres
•Gyri: folds
•Sulci: grooves
•Corpus callosum: bridge connecting two hemispheres
•Surface of the cortex
–Motor areas control muscular movements
–Sensory areas interpret sensory impulses
–Association areas process emotions and intellect
•Cerebral hemispheres
–Frontal lobe: muscle movement, moods, aggression, smell, motivation
–Parietal lobe: touch, pain, balance, taste, temperature
–Temporal lobe: hearing, smell, memory, abstract thought, judgment
–Occipital lobe: vision
•Cerebral cortex
•Cerebral cortex: gray matter surface
•Longitudinal fissure
•Longitudinal fissure separates two hemispheres
•Gyri:
•Gyri: folds
Sulci:
•Sulci: grooves
•Corpus callosum
•Corpus callosum: bridge connecting two hemispheres
•Surface of the cortex
•Surface of the cortex
–Motor areas control muscular movements
–Sensory areas interpret sensory impulses
–Association areas process emotions and intellect
•Cerebral hemispheres
•Cerebral hemispheres
–Frontal lobe: muscle movement, moods, aggression, smell, motivation
–Parietal lobe: touch, pain, balance, taste, temperature
–Temporal lobe: hearing, smell, memory, abstract thought, judgment
–Occipital lobe: vision
The Cerebellum: Structure and Function
•Butterfly-shaped •Two partially separated hemispheres connected by vermis •Functions –Coordinating muscular movements –Maintaining posture –Maintaining balance
The Autonomic Nervous System
•Subdivision of efferent PNS•Functions without conscious effort
•Regulates functions of internal organs
•Assists in maintaining homeostasis
•Helps deal with emergency situations
•Sympathetic
–Energy and stressful situations–Increases heartbeat and breathing rates
–Neurotransmitters: acetylcholine and norepinephrine
•Parasympathetic
–Restores body to nonstressful state
–Neurotransmitter: acetylcholine
–Stimulates digestion, urination, and defecation
The 12 Cranial Nerves and Their Functions
- (I) Olfactory: smell
- (II) Optic: sight
- (III) Oculomotor: movement of eyeball, constriction of pupil
- (IV) Trochlear: movement of eyeball
- (V) Trigeminal: chewing, sensations in teeth
- (VI) Abducens: movement of eyeball
- (VII) Facial: facial expression, taste, tear and salivary glands
- (VIII) Vestibulocochlear: equilibrium, hearing
- (IX) Glossopharyngeal: swallowing, taste, salivary glands
- (X) Vagus: certain muscle movements, sensory impulses
- (XI) Accessory: swallowing, head movement
- (XII) Hypoglossal: swallowing, speech
- (I) Olfactory: smell
- (II) Optic: sight
- (III) Oculomotor: movement of eyeball, constriction of pupil
- (IV) Trochlear: movement of eyeball
- (V) Trigeminal: chewing, sensations in teeth
- (VI) Abducens: movement of eyeball
- (VII) Facial: facial expression, taste, tear and salivary glands
- (VIII) Vestibulocochlear: equilibrium, hearing
- (IX) Glossopharyngeal: swallowing, taste, salivary glands
- (X) Vagus: certain muscle movements, sensory impulses
- (XI) Accessory: swallowing, head movement
- (XII) Hypoglossal: swallowing, speech
- (I) Olfactory: smell
- (II) Optic: sight
- (III) Oculomotor: movement of eyeball, constriction of pupil
- (IV) Trochlear: movement of eyeball
- (V) Trigeminal: chewing, sensations in teeth
- (VI) Abducens: movement of eyeball
- (VII) Facial: facial expression, taste, tear and salivary glands
- (VIII) Vestibulocochlear: equilibrium, hearing
- (IX) Glossopharyngeal: swallowing, taste, salivary glands
- (X) Vagus: certain muscle movements, sensory impulses
- (XI) Accessory: swallowing, head movement
- (XII) Hypoglossal: swallowing, speech
- (I) Olfactory: smell
- (II) Optic: sight
- (III) Oculomotor: movement of eyeball, constriction of pupil
- (IV) Trochlear: movement of eyeball
- (V) Trigeminal: chewing, sensations in teeth
- (VI) Abducens: movement of eyeball
- (VII) Facial: facial expression, taste, tear and salivary glands
- (VIII) Vestibulocochlear: equilibrium, hearing
- (IX) Glossopharyngeal: swallowing, taste, salivary glands
- (X) Vagus: certain muscle movements, sensory impulses
- (XI) Accessory: swallowing, head movement
- (XII) Hypoglossal: swallowing, speech
- (I) Olfactory: smell
- (II) Optic: sight
- (III) Oculomotor: movement of eyeball, constriction of pupil
- (IV) Trochlear: movement of eyeball
- (V) Trigeminal: chewing, sensations in teeth
- (VI) Abducens: movement of eyeball
- (VII) Facial: facial expression, taste, tear and salivary glands
- (VIII) Vestibulocochlear: equilibrium, hearing
- (IX) Glossopharyngeal: swallowing, taste, salivary glands
- (X) Vagus: certain muscle movements, sensory impulses
- (XI) Accessory: swallowing, head movement
- (XII) Hypoglossal: swallowing, speech
•(I) Olfactory
•(I) Olfactory: smell
•(II) Optic:
•(II) Optic: sight
•(III) Oculomotor:
•(III) Oculomotor: movement of eyeball, constriction of pupil
•(IV) Trochlear:
•(IV) Trochlear: movement of eyeball
•(V) Trigeminal:
•(V) Trigeminal: chewing, sensations in teeth
•(VI) Abducens:
•(VI) Abducens: movement of eyeball
•(VII) Facial:
•(VII) Facial: facial expression, taste, tear and salivary glands
•(VIII) Vestibulocochlear:
•(VIII) Vestibulocochlear: equilibrium, hearing
•(IX) Glossopharyngeal:
•(IX) Glossopharyngeal: swallowing, taste, salivary glands
•(X) Vagus:
•(X) Vagus: certain muscle movements, sensory impulses
•(XI) Accessory:
•(XI) Accessory: swallowing, head movement
•(XII) Hypoglossal:
•(XII) Hypoglossal: swallowing, speech
The Special Senses
- The Sense of Smell
- The Sense of Taste
- The Sense of Sight
- The Sense of Hearing and Equilibrium
The Sense of Smell
- Molecules in air dissolve in nasal mucus
- Bipolar sensory neurons transfer chemical impulse
- Olfactory bulbs receive impulse
- Impulse sent to olfactory cortex
- Odor variety dependent on brain interpretation
The Sense of Taste
- Taste buds on tongue, palate, and pharynx
- Taste bud cell types–Exterior capsule: epithelial cells–Interior: taste cells
- Taste depends on chemicals dissolved in saliva
- Taste influenced by olfactory sensations
The Sense of Sight
•Eyes protected by eyelids and eyelashes •Tears –Lubricate the eyes –Contain bacteriolytic lysozyme enzyme –Contain salt and gamma globulin
The Sense of Hearing and Equilibrium
•Outer ear
–Auricle: external, visible, flexible part
–External auditory meatus
•Lined with hair and ceruminous glands
–Tympanic membrane: vibrates in response to sound
•Middle ear
–Auditory ossicles: malleus, incus, and stapes
–Openings: oval and round windows
–Eustachian tube: equalizes pressure
•Inner ear
–Cochlea: hearing
–Equilibrium•Static: vestibule
•Kinetic: semicircular canals
•Outer ear
•Outer ear
–Auricle: external, visible, flexible part
–External auditory meatus
•Lined with hair and ceruminous glands
–Tympanic membrane: vibrates in response to sound
•Middle ear
•Middle ear
–Auditory ossicles: malleus, incus, and stapes
–Openings: oval and round windows
–Eustachian tube: equalizes pressure
•Inner ear
•Inner ear
–Cochlea: hearing
–Equilibrium•Static: vestibule
•Kinetic: semicircular canals
•Molecules in air dissolve where?
in nasal mucus
•Bipolar sensory neurons transfer what?
chemical impulse
•Olfactory bulbs receive what?
impulse
•Impulse sent where?
to olfactory cortex
•Odor variety dependent on what?
brain interpretation
•Taste buds reside on?
on tongue, palate, and pharynx
•Taste bud cell types
Exterior capsule: epithelial cells
–Interior: taste cells
•Taste depends on what?
chemicals dissolved in saliva
•Taste influenced by what?
by olfactory sensations
•Eyes protected by what?
eyelids and eyelashes
•Tears
–Lubricate the eyes
–Contain bacteriolytic lysozyme enzyme
–Contain salt and gamma globulin
The Endocrine System Introduction
•Maintains internal environment (homeostasis)
•Hypothalamus: sends chemical signals to pituitary
•Endocrine glands
–Ductless
–Secrete hormones directly into bloodstream
The Functions of Hormones
•Control cellular respiration, growth, and reproduction
•Control body fluids and electrolyte balance
•Control secretion of other hormones
•Control behavior patterns
•Regulate reproductive cycles, growth, and development
•Chemical control functions as negative feedback loop
–Thermostat turns furnace on when temperature falls below set point
•Hormones function similarly
The Classification of Hormones
•Modified amino acids –Epinephrine, oxytocin•Proteins –Insulin, growth hormones •Steroid –Cortisol, estrogen
The Hypothalamus of the Brain
•Controls secretions of the pituitary gland
•Nerve cells produce chemical signals
–Releasing hormones
–Releasing inhibitory hormones
–Controlled by negative feedback from endocrine system
The Major Endocrine Glands and Their Hormones
The Anterior Pituitary Gland, Its Hormones, and Some Disorders
The Anterior Pituitary Gland, Its Hormones, and Some Disorders
•Growth hormone (GH): cell metabolism and growth
–Decreased production
•Dwarfism: childhood
–Increased production
•Gigantism: childhood
•Acromegaly: post puberty
–Controlled by two releasing hormones from hypothalamus
•Thyroid-stimulating hormone (TSH): stimulates thyroid
•Adrenocorticotropic hormone (ACTH): stimulates adrenal cortex
•Melanocyte-stimulating hormone (MSH): stimulates melanocytes
•Follicle-stimulating hormone (FSH)
–Females
•Stimulates ovarian follicle development
–Males
•Stimulates sperm cell production
•Luteinizing hormone (LH)
–Females•Stimulates ovulation and progesterone production
–Males
•Testosterone production
•Lactogenic hormone (prolactin): stimulates milk production in females
–May cause decrease in male sex hormones
The Posterior Pituitary Gland and Its Hormones
•Antidiuretic hormone (ADH)
–Increased water reabsorption in kidney tubules
–Deficiency results in diabetes insipidus
–Regulated through osmoreceptors
•Dehydration causes water conservation
•Oxytocin
–Contraction of uterine smooth muscles
–Constriction of mammary gland cells (lactation)
–Given after childbirth to constrict blood vessels to minimize risk of hemorrhage
The Thyroid Gland, Its Hormones, and Some Disorders
•Located below larynx on either side of trachea •Requires iodine •Hormones –Thyroxine (T4): metabolism –Triiodothyronine (T3): metabolism –Calcitonin: regulation of calcium and phosphate concentration •Hypothyroidism –Cretinism –Lowered metabolic rate –Myxedema •Hyperthyroidism –Elevated metabolism –Graves’ disease •Exophthalmia
The Parathyroid Glands, Their Hormones, and Some Disorders
•Located within the posterior thyroid gland•Chief cells secrete parathormone (PTH)
•PTH stimulates bone cell release of calcium and phosphate
•Hyperparathyroidism
–Breakdown of bone matrix
•Hypoparathyroidism
–Low calcium level in blood
The Adrenal Glands, Their Hormones, and Some Disorders
•Located on top of each kidney
•Adrenal medulla: epinephrine and norepinephrine
•Adrenal cortex: aldosterone, cortisol, androgens
•Disorders
–Addison’s disease: lack of adrenal cortex hormones
–Cushing’s syndrome: too much adrenal cortex hormones
The Pancreas, Its Hormones, and Some Disorders
•Islets of Langerhans•Beta cells: insulin production
•Alpha cells: glucagon production
•Blood glucose levels regulated by negative feedback
•Disorders
–Low blood glucose: acidosis
–High blood glucose: excess kidney production, dehydration
–Diabetes mellitus: insufficient insulin production
The Testes and the Ovaries
- Testes: testosterone–Development of male reproduction structures–Development of male sex characteristics
- Ovaries: estrogen and progesterone–Development of female reproductive organs–Development of female sex characteristics–Control menstrual cycle
The Thymus Gland and Its Hormone
- Located behind the sternum
- Secretes thymosin
- Important for T cell production
- Thymus shrinks as we age
The Pineal Gland and Its Hormone
•Located in the brain near the thalamus •Melatonin –Inhibits reproductive functions –Regulates body rhythms •Serotonin: neurotransmitter and vasoconstrictor –Stimulates smooth muscle contractions
the semitendinosus has
a really long tendon
rectus means
straight up and down
gracilis is
the most medial muscle
the tibia is on the
big toe side
the fibula is on the
little toe side
the fibula is also known as
peroneus longus
anterior leg muscle=
extends foot/toes
posterior leg muscles=
flexes foot/toes
hallucis=
big toe
the big toe is medial or lateral
medial
little toe os medial or lateral
lateral
ab - ductor
away from midline
ad- ductor
towards the midline
interossei
in between bones
flaccid
limp
trophic
growth
hyper
alot
atrophy
no growth
myo =
muscle
myalgia ==
pain
my =
muscle
The Nervous System
Introduction, Spinal Cord and Spinal Nerves
Control center and communication network
Directs functions of body’s organs and systems
Interprets external environment
Determines reaction to change
Homeostasis: balanced internal environment
Controlled by nervous and endocrine systems
Organization of nervous system
Central Nervous System (CNS)- BRAIN and SPINAL CORD
Peripheral Nervous System (PNS)- NERVES
AFFERENT peripheral system (Sensory neurons)
EFFERENT peripheral system (motor neurons)
Somatic- conducts impulses from the brain & spinal cord to skeletal muscle
Autonomic Nervous System (ANS): conducts impulses from the brain & spinal cord to smooth muscle tissue, cardiac tissue, & the glands
Sympathetic (SANS): Stimulates & speeds up metabolic actions
‘Fight or Flight’ Response (i.e. heart rate & sweating)
Parasympathetic (PANS): Slows down metabolic actions:
Stimulate digestion, urination, and defecation:
“Rest & Digestion” Response
Classification of Nerve Cells
Provide unique functions
Sensing, thinking, remembering, controlling, muscle activity, regulating glandular secretions
Support, protect, & nourish the neurons
Maintains homeostasis in the interstitial fluid that bathes it
Neuroglia Cells (Support Cells)
**60% of ALL Brain Cells!
Astrocytes: support, connection, blood brain barrier
Oligodendroglia: support, myelin sheath formation in central nervous system (CNS)
Schwann: myelin sheath formation in peripheral nervous system (PNS)
Microglial: phagocytosis
Ependymal: line the ventricles of the brain
The Structure of a Neuron
Cell body: Control Center Dendrites: receptive areas Axon: extension of cell body Schwann cells- myelinated portions Nodes of Ranvier- unmyelinated portions Multipolar: several dendrites coming off cell body; ** Most common! Most MOTOR neurons Bipolar: one dendrite and one axon Most INTERNEURONS neurons Unipolar: one process extending from cell body Most SENSORY neurons
The Structure of a Neuron 3
Receptors: detect environmental stimuli
Sensory (afferent) neurons:
Receive stimulus impulse from receptor site
Carry impulses to the brain
Internuncial (Interneurons):
transmit impulse for interpretation and processing
Carry impulses between neurons
Motor (efferent) neurons:
React to the stimulus
Carry impulses from the brain to “effector” organs
The Physiology of the Nerve Impulse
Concentration of electrolytes: Na+ (sodium) higher on outside K+ (calcium) higher on inside Resting potential: charge outside positive and inside negative Action (Electrical) Potential: rush of Na+ inside cell AKA “Depolarization” Repolarization: K+ moves outside cell attempting to balance change in charges
The Physiology of the Nerve Impulse- Depolarization : Repolarization
Depolarization:
Na+ rush inside cell
Repolarization:
K+ rush out to restore balance
Depolarization: Repolarization
moves in ONE direction
The Synaptic Transmission
SYNAPSE: axon terminal branches close to next dendrites
Impulse reaches axon terminals
Triggers neurotransmitter release into synaptic cleft
Major Neurotransmitters (NTs): Acetylcholine Most common primary NT of the PANS Epinephrine Norepinephrine primary NT of the SANS Serotonin Dopamine Endorphins
The Reflex Arc
Involuntary reaction to external stimulus i.e. Knee-jerk reflex Homeostasis maintenance Examples: Heartbeat/breathing rates Digestion Coughing Sneezing Swallowing Vomiting Involuntary reaction to external stimulus
Grouping of Neural Tissue
White matter Groups of myelinated axons Forms nerve tracts in CNS Gray matter Nerve cell bodies and dendrites Unmyelinated axon bundles Cortex: gray matter on surface of brain Horns: gray matter in spinal cord
Neural tissue consists of the primary components (axon, cell body, & dendrites) of a neuron:
Nerve: bundle of fibers (axons) inside the PNS
Tract: bundle of fibers (axons) inside the CNS
Ganglia: neuron cell bodies inside the PNS
Nucleus: neuron cell bodies and dendrites inside the CNS
The Spinal Cord’s Anatomy
Continuation of the brain’s medulla oblongata
31 segments; each has a pair of spinal nerves
Protected by meninges:
Dura mater (“Tough mother”)- outermost layer
Arachnoid (“Web”)- middle layer
Pia mater (“Delicate mother”)- innermost layer
Functions of the Spinal Cord
Conveys sensory impulses to the brain Integrates reflexes Spinal nerves connect at roots Dorsal (posterior) root: sensory Ventral (anterior) root: motor
The Spinal Nerves’ Anatomy
All 31 pairs arise from union of dorsal and ventral roots
Mixed nerves consisting of motor and sensory fibers
Most exit vertebral column between vertebrae
The Spinal Nerves’ Anatomy
Named and numbered according to region and level of spinal cord Cervical: 8 pairs Thoracic: 12 pairs Lumbar: 5 pairs Sacral: 5 pairs Coccygeal: 1 pair
Drugs that Act on the CNS: Depressants
Valium
Low Doses: Relieves tension
High Doses: Drowsiness, Sedation, and Loss of any pain sensations
Opiates (i.e. Codeine and Heroin)
Sedatives and Analgesics; Euphoria
Overuse: coma, convulsions, and respiratory problems that could lead to death
Marijuana- from hemp plant; produces Euphoria
Hashish- more potent cousin of marijuana (come from different part of hemp plant)
produces Euphoria AND alters perception of time and space.
Overuse: Hallucinations, Respiratory Problems
Drugs that Act on the CNS: Stimulants
Cocaine Euphoria (quick) Overuse: Changes in personality, seizures, and death (from stroke or abnormal rhythms of the heart) LSD Heightened & Exaggerated 5 senses
Amphetamines- Over-stimulate postsynaptic neurons:
Euphoria, Muscle spasms, restlessness, rapid heartbeat, & hypertension
Overuse: Death (from respiratory or heart failure)
Drugs that Act on the CNS: Hallucinogens
LSD
Heightened & Exaggerated 5 senses
A Stimulant
Drugs that Act on the CNS: Anabolic Steroids
Act like the male sex hormones Cause skeletal muscle cells to increase in size Overuse: negative feedback effect on the hypothalamus of the brain and the pituitary gland In sex hormones In testes size & sterility Liver Problems Heart Disease Anger
Afferent peripheral system (sensory neurons)
carries info to the brain
efferent peripheral system (motor neurons)
carry info away from the brain
Microglial: phagocytosis
(swallowing of foreign agents)
The Structure of a Neuron 2
Multipolar: several dendrites coming off cell body; ** Most common!
Most MOTOR neurons
Bipolar: one dendrite and one axon
Most INTERNEURONS neurons
Unipolar: one process extending from cell body
Most SENSORY neurons
C-ome L-ets G-et S-un B-urned
statum corneum- protection keritinized cells stratum lucidum- clear stratum germanium statum spnosom statum basale - where new cells are made
synarthrosis
don't move made of har cartilage fixed fibrocartilage syndesmosis (ligament)
amphiarthrosis
slightly moveable
fibrocartilage
hyaline cartilage
diarthrosis (synovial)
freely moving
hyaline
6 synovial joints
- ball and socket
- pivot
- hinge
- saddle
5 condyloid
6 gliding
main Parts of the Brain
MAIN PARTS Brainstem Diencephalon Cerebrum Cerebellum
protection parts of the brain
PROTECTION
Cranial bones
Meninges
Cerebrospinal fluid
Ventricles of the brain
VENTRICLES
4 Ventricles
Interventricular foramen
Brain stem parts
Midbrain
Pons
Medulla
parts of the Diencephalon
Diencephalon
Thalamus
Hypothalamus
The Principal Parts of the Brain: PROTECTION
PROTECTION Cranial bones Meninges Epidural Space Dura Mater Subdural Space Arachnoid Mater Subarachnoid Space Pia Mater Cerebrolspinal fluid (CSF) Inside the subrachnoid space
The Principal Parts of the Brain: VENTRICLES (Sagittal Cross Sectional View)
VENTRICLES- Spaces where CSF is produced and circulated
4 Ventricles
Interventricular foramen- connects the Lateral Ventricles with the
3rd Ventricle
Cerebral Aqueduct- connects the 3rd & 4th Ventricles
Midbrain
Midbrain
Ventral cerebral peduncles: convey impulses from cortex to pons and spinal cord
Dorsal tectum: reflex center
Controls movement of head and eyeball (visual stimuli)
Controls movement of head and trunk (auditory stimuli)
Pons varolii
Pons varolii
Connects spinal cord with brain
Connects parts of brain with each other
Helps control breathing
Medulla oblongata
Medulla oblongata Ascending and descending tracts Connect spinal cord with the brain Some tracts cross over in medulla Reticular formation: controls consciousness Reflex centers
Diencephalon:
Diencephalon: Optic Tracts Mammillary bodies Thalamus Epithalamus Houses Pineal gland Hypothalamus Optic tracts: Visual Relay System Mammillary bodies: Memory and emotional responses Thalamus Relay station for sensory impulses Interpretation center for pain, temperature and touch Epithalamus: contains Pineal gland Hypothalamus:
Hypothalamus:
Hypothalamus: Homeostasis
Controls and integrates autonomic nervous system
Receives sensory impulses from internal organs
Controls the Pituitary gland (linked via the Infundibulum) and links endocrine and nervous systems
The Cerebrum Structure and Function
Cerebral cortex: gray matter surface
Longitudinal fissure: separates two hemispheres
Gyri: folds
Sulci: grooves
Corpus callosum: bridge connecting two hemispheres
Cerebral cortex:
Cerebral cortex: gray matter surface
Longitudinal fissure:
Longitudinal fissure: separates two hemispheres
Gyri:
Gyri: folds
Sulci:
Sulci: grooves
Corpus callosum:
Corpus callosum: bridge connecting two hemispheres
Surface of the cortex
Motor areas control muscular movements
Sensory areas interpret sensory impulses
Association areas process emotions and intellect
Cerebral hemispheres
Cerebral hemispheres Frontal lobe: Parietal lobe: Temporal lobe: Occipital lobe:
Frontal lobe:
Frontal lobe: muscle movement, moods, aggression, smell, motivation
Parietal lobe:
Parietal lobe: touch, pain, balance, taste, temperature
Temporal lobe:
Temporal lobe: hearing, smell, memory, abstract thought, judgment
Occipital lobe:
Occipital lobe: vision
The Cerebellum: Structure
Butterfly-shaped
Two partially separated hemispheres connected by vermis
The Cerebellum: Function
Reflex center in coordinating complex skeletal muscular movements
Maintaining posture
Maintaining balance
The Autonomic Nervous System
Subdivision of efferent PNS Functions without conscious effort Regulates functions of internal organs Assists in maintaining homeostasis Helps deal with emergency situations
The Autonomic Nervous System: Sympathetic
Sympathetic
“ Fight or Flight” Response
Energy and stressful situations
Increases heartbeat and breathing rates
Neurotransmitters: Acetylcholine and Norepinephrine
The Autonomic Nervous System: Parasympathetic
Parasympathetic
“ Rest & Digest” Response
Restores body to nonstressful state
Stimulates digestion, urination and defecation
Neurotransmitter: Acetylcholine
The 12 Cranial Nerves and Their Functions (cont’d.)
(I) Olfactory: smell (II) Optic: sight (III) Oculomotor: movement of eyeball constriction of pupil (via parasympathetic nervous system) (IV) Trochlear: movement of eyeball (down & in)
(I) Olfactory:
(I) Olfactory: smell
(II) Optic:
(II) Optic: sight
(III) Oculomotor:
(III) Oculomotor:
movement of eyeball
constriction of pupil
(via parasympathetic nervous system)
(IV) Trochlear:
(IV) Trochlear: movement of eyeball (down & in)