Fibrous and fibro-osseous tumor

Question 1

what is Fibrous dysplasia?

what characterizes fibrous dysplasia?

what are the bones mostly affected by this?

Answer 1

Benign non-neoplastic process of bones.

1. replacement of marrow by fibrous tissue.
2. presence of poorly formed woven bone arranged in Chinese letter pattern.

ribs, femur, or cranial bones of children and young adults.

Question 2

what are the types of fibrous dysplasia?

Answer 2

1. Monostotic fibrous dysplasia
2. Polystotic fibrous dysplasia
3. McCune-Albright syndrome

Question 3

what is Monostotic fibrous dysplasia?

what is Polystotic fibrous dysplasia?

Answer 3

Involvement of single bone and asymptomatic

there is Involvement of Multiple bones, is symptomatic, you see deformities and fractures of craniofacial bones, can see Shepherd Crook deformity of proximal femur.

Question 4

what is McCune-Albright syndrome?

what can occur secondary to this disease?

Answer 4

Polystotic disease with precocious sexual development with café-au-lait spots

Secondary sarcoma may develop after irradiation (rarely).