Female genitourinary tract

Question 1

what are the vulva disorders?

Answer 1

1. Bartholin gland abscess*
2. Condyloma acuminata*
3. Extramammary Paget’s Disease*

Question 2

what is this?

Answer 2

Bartholin gland abscess

Question 3

what is this?/

Answer 3

Exudation associated with Bartholin gland abscess

Question 4

what is a Bartholin gland abscess?

Answer 4

happens because of occlusion of duct of Bartholin vulvovginal glands due to infection with N. gonorrhoeae

Question 5

what is this?

Answer 5

Condyloma Acuminatum, venereal warts, HPV, Human Papillomavirus

Question 6

what is this?

Answer 6

HPV 6 or 11

episomal form

Question 7

what is Condyloma Acuminatum?

what causes it?

what is seen at micro level?

Answer 7

Is a wart like, verrucous lesion.

HPV 6 or 11

lesion with proliferation of stratified squamous epithelium and some cell have perinuclear clearing (koilocytosis)

Question 8

how does extra-mammary Paget’s Disease?

In what body part does it appear mostly?

malignant HPV cell contain what? what stain can be used? what can it lead to?

Answer 8

red, crusted sharply demarcated, maplike lesions.

labia majora

mucin, PAS, intraepithelial adenocarcinoma

Question 9

what is this?

Answer 9

Extra- mammary Paget’s Disease

Question 10

what is being shown in both pictures?

Answer 10

malignant cells

up - malignant paget’s cells

down - malignant pagets cells with mucin

Question 11

extra mammary pagets tumors are derived from what cells?

most lesions are usually found where?

how does it spread?

Answer 11

primitive epithelial progenitor cells

in the epidermis

pagetoid spread = along the epithelium

Question 12

what are the Disorders of Vagina?

Answer 12

1. Embryonal Rhabdomyosarcoma*
2. Vaginal adenosis and clear cell adenocarcinoma*

Question 13

what is this?

Answer 13

embryonal rhabdomyosarcoma

Question 14

what is another name for lesion presentation?

Answer 14

grape-like tumor

Question 15

what is another name for Embryonal Rhabdomyosarcoma?

who does it affect?

how does it present grossly?

Answer 15

Sarcoma Botryoides

girls younger than 5 years

grape-like mass protruding from the vagina

Question 16

what do you find at micro level on a rhabdomyosarcoma?

Answer 16

• Spindle shaped tumor (rhabdomyoblasts) cells with rare cross striations (evidence of skeletal muscle differentiation)
• Cambium layer: tendency of tumor to grow beneath the vaginal epithelium

Question 17

rhabdomyosarcoma cells will stain with what?

how will it spread?

Answer 17

desmin

through the blood

Question 18

on who does Vaginal adenosis and clear cell adenocarcinoma occur?

Answer 18

women exposed to Diethylstilbesterol (DES) in utero

Question 19

what is this?

Answer 19

vaginal adenosis