Fibromylagia Flashcards
Fibromyalgia
A condition of chronic widespread pain and abnormal pain processing mechanisms.
Fibromyalgia: Symptoms
Pain
Fatigue, sleep disturbance, stiffness, headaches, bowel disturbances, anxiety and depression.
Fibromyalgia: Causes and risk factors
- Trauma ― physical and emotional, HPAA dysregulation
- Hypothyroidism
- SIBO
- Dybiosis
- GBA
- Infections - EBV
- Nutritional deficiencies: Vit D, B12 and Mg
- Gluten
- Genetics (MTHFR, COMT)
- Heavy metals
Fibromyalgia: Natural approach
- PK diet?
- Gluten-free diets
- Low FODMAP diet
- Support the thyroid, adrenals, GIT as needed.
- Reduce glutamate levels
Fibromyalgia: Supplements
Magnesium
Vitamin D
Vitamin B6
CoQ10
5-HTP
Fibromyalgia: Mg
Dose: 200-500mg
NMDA antagonist
Anti-nociceptive - analgesic
Fibromyalgia: Vit D
Modulate central pain
Reduces PGE2
Fibromyalgia: Vitamin B6
50-100mg
Co-factor for conversion of glutamate to GABA
Fibromyalgia: CoQ10
Dose: 300mg daily
Antioxidant
Mitochondrial dysfunction
Electron transport chain
Fibromyalgia: 5-HTP
Dose: 100-300mg/day
- 5 - HTP is the direct precursor to serotonin,
which plays a role in descending pain regulation.
Fibromyalgia: Herbs
Ashwagandha - HPA axis and GABA
St Johns Wort - increases seratonin and dopamine
Devil’s Claw - Anti-inflammatory
Fibromyalgia: Other
Reduce toxic load
Chelate heavy metals
Optimise glutathione
Saunas
Epsom salts
Support methylation
Support sleep
Exercise
Support stress
Tissue sales
Capaicin -> substance P