Chronic Inflammation Flashcards
Chronic Inflammation
Vasodilation
Blood clotting
Oedema
Recruitment of immune cells
Signs:
Redness
Heat
Oedema
Pain
Chronic Inflammation: Pathophysiology
Cytokines (TNF-a, Il-1,6)
Histamine
Kinins
NF-kB
PGE-2
Chronic Inflammation: Eicosonaids
Hormone-like messagers made by oxidation of omega 3 and 6 fats.
Inflammation resolution
T-Reg cells
PGE-1 and 3, Resolvins and protectins
Chronic inflammation: Causes and risk factors
Refined sugar
High Omega 6/3 ratio
FADS1,2 polymorphisms
Obesity
Chronic stress
Sleep
Over-exercise
Oxidative stress
Toxic load
Metabolic endotoxaemia
Persistant or latent infection
Chronic Inflammation: Supplements
COPED GB
Curcumin
OPCs
Plant sterols
EFAs
Vitamin D
Ginger
Boswelia
Chronic Inflammation: Curcumin
Il-6, TNF-a
Chronic inflammation: OPCs
COX-2
Chronic inflammation: Plant sterols
Il-6, TNF-a
Chronic Inflammation: EFAs
Il-6, TNF-a
Chronic Inflammation: Vitamin D
T-reg - immunomodulator
Il-6, TNF-a
Chronic Inflammation: Ginger
Cox-2
Chronic Inflammation: Boswelia
Pain
5-Lox