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Cardiovascular SOH > Fibrinolytic drugs > Flashcards

Fibrinolytic drugs Flashcards

1
Q

Fibrinolytics (mechanism)

A

Used to re-open occluded arteries by breaking down clots
Plasminogen is converted to plasmin
Plasmin converts fibrin to fibrin fragments
Clot lysis

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2
Q

Fibrinolytics (administration)

A

IV

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3
Q

Fibrinolytic examples

A

Streptokinase
Alteplase
Duteplase

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4
Q

Streptokinase

A

Extracted from strep cultures
Action: activates plasminogen
Action is blocked after 4 days due to generation of antibodies
Do not give further doses

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5
Q

Alteplase and duteplase

A

Action: activates plasminogen

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Cardiovascular SOH (42 decks)

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