Anti-platelets Flashcards
1
Q
Drug names
A
Aspirin
Clopidogrel
Ticagrelor
Tirofiban
2
Q
Uses
A
Arterial circulation (as anticoagulants are not effective here) Thromboprophylaxis Angina MI Stroke Primary prevention Secondary prevention
3
Q
Aspirin (mechanism)
A
Prevents platelets clumping together
Irreversibly blocks COX synthesis
This prevents TXA2 synthesis
4
Q
Aspirin (administration)
A
Oral
75mg daily
5
Q
Aspirin (adverse effects)
A
GI bleeding
Ulceration
6
Q
Clopidogrel (mechanism)
A
Prevents platelets clumping together
Prevents ADP from binding to it’s receptors
7
Q
Clopidorgrel (administration)
A
Oral
8
Q
Tirofiban (mechanism)
A
Short term treatment to prevent MI in high risk patients with unstable angina
9
Q
Tirofiban (administration)
A
IV
