Fetal Development and Stress Flashcards
What is Barkers Hypothesis
heart disease, type 2 diabetes, stroke, hypertension originate in response to undernutrition during fetal life
What is programming hypothesis?
non-genetic factors can organize or imprint permanently on physiological system
What is the role of the HPA axis during pregnancy?
estrogen stimulates cortisol porduction, and there is more estrogen during pregnancy, therefore, higher cortisol
What are some positive aspects of stress during pregancy?
- influence growth in uterus, activity of pancreas
- maturation of organ system
- accelerate lung maturation, decreases respiratory distress syndrome
How can moderate levels of stress be beneficial for optimal developement?
- sensitizes developing nervous system
- develops adaptive response to stress
What are physiological impacts of maternal stress?
- increase infant mortality and preterm births
- decrease birth weight
- HPA axis response
What are psychological impact of maternal stress?
- long-term psychological effects
1. deficits learning and memory
2. temperament
3. ADHD
4. Schizophrenia
What are the types of stress?
- chronic stress
- pregnancy specific anxiety (PSA)
What are some consequences of chronic stress?
linked to delayed language developement and lower intellectual functioning
What are some consequences of PSA
- shorter gestation
- decreased mental and motor developement
- disruptive temperament and attention regulation problems
What are the threats to normal fetal development?
- susceptible to damage
- environmental factors that interfere with growth during critical period
- differs depending on system or organ
What threats affect the developmental process?
- teratogen in early pregnancy may result in major structural malformation
- same teratogen later may result in neurobehavioral deficits
What are the results of severe life event stress in the first trimester for the baby?
more congenital abnormalities, defect cranial-neural crest and derived organs
What are the results of high maternal anxiety in the second trimester for the baby?
atypical laterality
What are the result of severe stress and higher coritsol levels than normal in the third trimester for the baby?
more risk preterm labour, and premature delivery, infant will cry more, fussing and negative facial expressions.