Fetal Development Flashcards

1
Q

What is an acrosome?

A

Develops during maturation of the sperm. It contains digestive enzymes that help sperm across the corona radiata.

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2
Q

What is capacitation?

A

Process that sperm goes through in crypts of female genital tract where it is fed and prepared to make it responsive to female environment.

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3
Q

The ovum is surrounded by what 2 walls?

A

Corona Radiata and Zona Pellucida.

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4
Q

What is Cortical Reaction?

A

When the Zona Pellucida blocks enzymes of any other sperm, preventing them from attaching.

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5
Q

What is the pre-embryonic stage?

A

From fertilisation to implantation.

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6
Q

What is the embryonic stage?

A

From implantation to week 8.

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7
Q

What is the fetal stage?

A

From week 9 to birth.

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8
Q

What 4 steps is the pre-embryonic stage made up of?

A

Zygote - Day 2 Embryo (cleavage) - Morula (3 days) - Blastocyst (10 days)

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9
Q

What is the bilaminar disc?

A

The embryoblast differentiates into two layers when implantation occurs; the epiblast and hypoblast.

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10
Q

What is Gastrulation?

A

The process of the bilaminar disc evolving into a trilaminar disc. It puts an end to the pre-embryonic state (at day 15).

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11
Q

What does the epiblast differentiate into during gastrulation?

A

Ectoderm. This forms skin, hair, nails etc.

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12
Q

What does the hypoblast differentiate into during gastrulation?

A

Endoderm. This forms glandular cells and lining of digestive and respiratory tracts.

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13
Q

What is the Primitive Streak?

A

A channel created by epiblast cells migrating inwards. More cells migrate through it between the 2 layers of bilaminar disc, forming the mesoderm layer.

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14
Q

What does the Mesoderm form?

A

Muscles, bones, blood and urogenital glands.

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15
Q

What is the notochordal process?

A

The creation of a tube that in the mesoderm by the ectoderm. It temporarily connects the amniotic cavity and yolk sac, providing pressure equilibrium.

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16
Q

What is the notochord?

A

The result of the closing of the tube created during notochordal process. Acts as a midline for tissues to follow in trilaminar disc and forms major structure of embryo.

17
Q

What is embryonic folding?

A

Occurs during the 4th week when trilaminar disc fold on horizontal and median planes, forming the embryo.

18
Q

What is the Primitive Gut?

A

Formed from the fusion of the endoderm to midline. It differentiates into foregut, midgut and hindgut.

19
Q

By what day is embryo folded and the end of embryonic state?

A

Day 25

20
Q

What is neurulation?

A

The formation of the neural tube which forms into the brain and spinal cord of the embryo.

21
Q

What is dextral looping?

A

During cardiac development, the atrium and ventricle are created by twisting rightward.

22
Q

What is the window of implantation?

A

The embryo sends chemical signals to tell the endometrium to be responsive to implantation for a very short period of time.

23
Q

What does the trophoblast differentiate into?

A

Cytotrophoblast and syncytiotrophoblast.

24
Q

What are chorionic villi?

A

Finger-like projections of the syncytiotrophoblast which feed the pregnancy.

25
Q

What does the Cytotrophoblast form?

A

The Chorionic Membrane (Chorion).

26
Q

What are the steps of fertilisation?

A
  1. Penetration of Corona Radiata
  2. Acrosome Reaction
  3. Cortical Reaction
  4. Gamete Fusion
  5. Meiosis Completion
27
Q

What are the steps of Gastrulation?

A
  1. Primitive Streak
  2. Mesoderm Development
  3. Notochordal Process
  4. Notochordal Plate
  5. Notochord Fusion