Fertilisation & meiosis Flashcards
Name the steps of fertilization
- Sperm transport
- Capacitation
- Acrosome
- Penetration
5.Cortical Reaction - Nuclear fusion
What is the fundamental idea of Fertilisation?
Sperm and egg create a zygote
What are the two stages of development?
Embryonic and Fetal
Describe the process of fertilisation.
The sperm capacitates at the zona pellucida of the egg, triggering an acrosome reaction. Once it penetrates, the egg undergoes cortical reaction to ensure no other sperm get in. Then, the sperm and egg nuclei fuse to form a diploid zygote with a complete set of chromosomes.
How does an embryo develop?
Cleavage: After fertilisation, the zygote undergoes rapid cell divisions (mitosis) without increasing in size, forming a ball of cells called a morula.
The morula becomes a blastocyst, which has a fluid-filled cavity. The blastocyst implants into the uterine wall around day 6-7.
What is meiosis?
Formation of egg and sperm cells that divide twice to form 4 daughter cells
Explain what the first meiotic division is
2 genetically different daughter cells have 4 chromatids. The chromosomes exchange genes by crossing over, inheriting a random assortment of genetic material.
Explain what the second meiotic division is
Amount of genetic material is halved; centromeres halved; 2 sister chromatids separate to opp. sides of cell and divide into 4 haploid daughter cells
2 identical forms of gene
Homozygous
2 different forms of gene
Heterozygous
Explain Prophase in PMAT
Prophase = chromosones condence and line up with homologous pairs (crossing over = genetic exchange)
Explain the MAT in PMAT
Metaphase = chromosones in the middle
Anaphase = chromosones are pulled away by spindle fibres
Telophase = 2 newly formed nuclei
In Meiotic 2, there is no ___
Crossing over or lining up in pairs
Prometaphase is
disappearance of envelope, fastening of sister chromatids and kinetochore function
What hormone is released during parturition?
Increase in Oxytocin - uterine contractions