Fertilisation & meiosis Flashcards

1
Q

Name the steps of fertilization

A
  1. Sperm transport
  2. Capacitation
  3. Acrosome
  4. Penetration
    5.Cortical Reaction
  5. Nuclear fusion
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1
Q

What is the fundamental idea of Fertilisation?

A

Sperm and egg create a zygote

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2
Q

What are the two stages of development?

A

Embryonic and Fetal

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2
Q

Describe the process of fertilisation.

A

The sperm capacitates at the zona pellucida of the egg, triggering an acrosome reaction. Once it penetrates, the egg undergoes cortical reaction to ensure no other sperm get in. Then, the sperm and egg nuclei fuse to form a diploid zygote with a complete set of chromosomes.

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2
Q

How does an embryo develop?

A

Cleavage: After fertilisation, the zygote undergoes rapid cell divisions (mitosis) without increasing in size, forming a ball of cells called a morula.

The morula becomes a blastocyst, which has a fluid-filled cavity. The blastocyst implants into the uterine wall around day 6-7.

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3
Q

What is meiosis?

A

Formation of egg and sperm cells that divide twice to form 4 daughter cells

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4
Q

Explain what the first meiotic division is

A

2 genetically different daughter cells have 4 chromatids. The chromosomes exchange genes by crossing over, inheriting a random assortment of genetic material.

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5
Q

Explain what the second meiotic division is

A

Amount of genetic material is halved; centromeres halved; 2 sister chromatids separate to opp. sides of cell and divide into 4 haploid daughter cells

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6
Q

2 identical forms of gene

A

Homozygous

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7
Q

2 different forms of gene

A

Heterozygous

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8
Q

Explain Prophase in PMAT

A

Prophase = chromosones condence and line up with homologous pairs (crossing over = genetic exchange)

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9
Q

Explain the MAT in PMAT

A

Metaphase = chromosones in the middle
Anaphase = chromosones are pulled away by spindle fibres
Telophase = 2 newly formed nuclei

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10
Q

In Meiotic 2, there is no ___

A

Crossing over or lining up in pairs

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11
Q

Prometaphase is

A

disappearance of envelope, fastening of sister chromatids and kinetochore function

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12
Q

What hormone is released during parturition?

A

Increase in Oxytocin - uterine contractions

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13
Q

In labour, there is a decline in

A

progesterone

14
Q

Phenotype

A

appearance or observable characteristic

15
Q

Genotype

A

genetic makeup of organism - individual collection

16
Q

If an egg is fertilised, it will burrow __

A

into the endometrium during implantation.

17
Q

When LH is present, the oocyte leaves the ruptured follicle, and it becomes

A

a corpus luteum which produces progesterone

18
Q

What does GnRH release in men?

A

Released by the hypothalamus and stimulates production of luteinizing hormone (LH) from the anterior pituitary.

19
Q

What does the ovary release?

A

Controlled by hypothalamus - it releases FST and LH - gonadotropins

20
Q

The release of oxytocin from posterior pituitary gland during labour is

A

a positive feedback loop - stimulates muscular contractions to push the baby