Female Genital Tract Flashcards

1
Q

Pus within tubal lumen

A

Pyosalpinx

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2
Q

Intestinal obstruction due to adhesions between small bowel and pelvic organs

A

Fitz-Hugh-Curtis syndrome (violin-string adhesions)

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3
Q

Treatment of bartholin cysts

A

Marsupialization

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4
Q

4 cardinal histologic features of Lichen Sclerosis

A
  1. Thinning of epidermis with disappearance of rete pegs
  2. Hydropic degeneration of basal cells
  3. Collagenous fibrous tissue replacement of dermis
  4. Monoclonal band like lymphatic infiltrates
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5
Q

White parchment-like patches of vulvar skin and labial atrophy

A

Lichen sclerosus (Chronic atrophic vulvitis)

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6
Q

Nonspecific condition arising from rubbing or scratching the skin presents with leukoplakia. (+) expansion of stratum granulosum

A

Lichen simplex chronicum

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7
Q

Etiologic factors of Condyloma acuminata

A

HPV 6 and 11

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8
Q

Vulvar cancer with infiltrating tumor characterized by nests and cords of malignant squamous cells

A

Basaloid carcinoma

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9
Q

Labia majora with maplike pruritic red crusts

A

Extramammary paget’s disease

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10
Q

Clear cell adenocarcinoma of the vagina

A

In utero exposure to Diethylstilbestrol (DES)

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11
Q

Derived from wolffian duct presenting with submucosal fluid-filled cyst

A

Gartner duct cyst

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12
Q

Area of predilection of vaginal cancer

A

Upper posterior vagina

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13
Q

A malignant embryonal rhabdomyosarcoma that present with polypoid rounded bulky masses projecting out of the vagina.

A

Sarcoma bortyoides (embryonal rhabdomyosarcoma)

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14
Q

Benign exophytic growths within endocervical canal that present with irregular vaginal bleeding.

A

Endocervical polyp

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15
Q

HPV strains implicated in cervical cancer

A

HPV 16, 18, 31, & 33 (can only infect immature cells at the squamocolumnar junction)

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16
Q

Most common histologic subtype of cervical cancer

A

Squamous cell carcinoma (80%)

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17
Q

Treatment of microinvasive carcinomas

A

Conization

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18
Q

Tx of invasive cervical ca

A

Radical hysterectomy with LND

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19
Q

Tx of St IIa-4 Cervical Ca

A

Radiotherapy

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20
Q

Moat common cause of death in cervical ca

A

Uremia (consequence of local extension)

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21
Q

Cervical ca screening recommendation

A

Begin 21yo or 3yrs after onset of sexual activity, annually thereafter

After 30yo with 3 consecutive normal cytology q2-3yrs

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22
Q

Recommended age for HPV vaccine

A

9-26yo

23
Q

Most common cause of dysfunctional bleeding

A

Anovulation

24
Q

Most common site of endometriosis

A

Ovaries

25
Q

Most widely accepted theory of endometriosis

A

Metastatic theory aka Regurgitation/implantation theory

Via retrograde menstruation

26
Q

Theory that explains occurrence of endometriosis in the lungs or lymph nodes

A

Vascular or lymphatic dissemination theory

27
Q

Most common presentation of endometriosis

A

Infertility

28
Q

Associated with prolonged estrogen stimulation of the endometrium, precursor lesion of endometrial carcinoma

A

Endometrial hyperplasia

29
Q

Endometrial hyperplasa that invariably leads to endometrial adenocarcinoma

A

Complex hyperplasia with atypia

30
Q

Most common invasive cancer of the female genital tract

A

Endometrial carcinoma

31
Q

Most common benign tumor in women

A

Myoma uteri

32
Q

Central pathologic abnormality is numerous cystic follicles/ follicle cysts (follicular hyperthecosis

A

PCOS

33
Q

Ovarian tumor with psammoma bodies

A

Serous tumor

34
Q

Psammoma bodies are found in these pathologic conditions

A
Papillary thyroid ca
Meningioma
Mesothelioma
Prolacitnoma
Serous cyst ca (ovary)

(MMPS)

35
Q

Rupture of mucinous tumors in the appendix or ovaries causing extensive mucinous ascites,cystic epithelial implants, and adhesions

A

Pseudomyxima peritoneii

36
Q

Brenner tumor of the ovary

A

Walthard cell rests

37
Q

Most common ovarian GCT

A

Mature teratoma aka dermoid cyst

38
Q

Ovary composed entirely of mature thyroid tissue causing hyperthyroidism

A

Struma ovarii

39
Q

Combination of struma ovarii and carcinoid in the same ovary

A

Strumal carcinoid

40
Q

Ovarian counterpart of seminoma
Usually unilateral with polyhedral cells dispersed in sheet or cords with scant fibrous stroma
Malignant
Responsive to chemo

A

Dysgerminoma

41
Q

Presence of schiller duval bodies. Rich in AFP and a1-antitrypsin

A

Yolk sac tumor

42
Q
Elaborates large amount of estrogen
Tumor marker (+) inhbin. With Call-Exner Bodies
A

Granulosa cell tumor

43
Q

Tumor that contains sertoli cells or leydig cell interspersed with stroma causing masculinazation/defeminazation

A

Androblastoma

44
Q

Mucin producing signet ring cancer cells that commonly has gastric origin with bilateral metastases

A

Krukenberg tumor

45
Q

Most common cause of spontaneous abortion

A

Chromosomal abnormality

46
Q

Pregnancy loss before 20wks AOG

A

Spontaneous abortion

47
Q

Most important predisposing condition of ectopic pregnancy

A

Prior PID

48
Q

Painless vaginal bleeding during 3rd trimester

A

Placenta previa

49
Q

Painful vaginal bleeding during the 3rd trimester

A

Placental abruption

50
Q

Karyotype of partial moles

A

69XXX
69XXY
69XYY (rare)

51
Q

H mole tumor marker

A

High bHCG for AOG

52
Q

Malignant and rapidly invasive neoplasm of trophoblastic cells

A

Choriocarcinoma

53
Q

Malignant trophoblastic cells diffusely infiltrating the endomyometrium.
High HPL

A

Placental Site trophoblastic tumor

54
Q

Pus collection within ovary and tubes

A

Tubo-ovarian abscess