Female Genital Tract

Question 1

Pus within tubal lumen

Answer 1

Pyosalpinx

Question 2

Intestinal obstruction due to adhesions between small bowel and pelvic organs

Answer 2

Fitz-Hugh-Curtis syndrome (violin-string adhesions)

Question 3

Treatment of bartholin cysts

Answer 3

Marsupialization

Question 4

4 cardinal histologic features of Lichen Sclerosis

Answer 4

1. Thinning of epidermis with disappearance of rete pegs
2. Hydropic degeneration of basal cells
3. Collagenous fibrous tissue replacement of dermis
4. Monoclonal band like lymphatic infiltrates

Question 5

White parchment-like patches of vulvar skin and labial atrophy

Answer 5

Lichen sclerosus (Chronic atrophic vulvitis)

Question 6

Nonspecific condition arising from rubbing or scratching the skin presents with leukoplakia. (+) expansion of stratum granulosum

Answer 6

Lichen simplex chronicum

Question 7

Etiologic factors of Condyloma acuminata

Answer 7

HPV 6 and 11

Question 8

Vulvar cancer with infiltrating tumor characterized by nests and cords of malignant squamous cells

Answer 8

Basaloid carcinoma

Question 9

Labia majora with maplike pruritic red crusts

Answer 9

Extramammary paget’s disease

Question 10

Clear cell adenocarcinoma of the vagina

Answer 10

In utero exposure to Diethylstilbestrol (DES)

Question 11

Derived from wolffian duct presenting with submucosal fluid-filled cyst

Answer 11

Gartner duct cyst

Question 12

Area of predilection of vaginal cancer

Answer 12

Upper posterior vagina

Question 13

A malignant embryonal rhabdomyosarcoma that present with polypoid rounded bulky masses projecting out of the vagina.

Answer 13

Sarcoma bortyoides (embryonal rhabdomyosarcoma)

Question 14

Benign exophytic growths within endocervical canal that present with irregular vaginal bleeding.

Answer 14

Endocervical polyp

Question 15

HPV strains implicated in cervical cancer

Answer 15

HPV 16, 18, 31, & 33 (can only infect immature cells at the squamocolumnar junction)

Question 16

Most common histologic subtype of cervical cancer

Answer 16

Squamous cell carcinoma (80%)

Question 17

Treatment of microinvasive carcinomas

Answer 17

Conization

Question 18

Tx of invasive cervical ca

Answer 18

Radical hysterectomy with LND

Question 19

Tx of St IIa-4 Cervical Ca

Answer 19

Radiotherapy

Question 20

Moat common cause of death in cervical ca

Answer 20

Uremia (consequence of local extension)

Question 21

Cervical ca screening recommendation

Answer 21

Begin 21yo or 3yrs after onset of sexual activity, annually thereafter

After 30yo with 3 consecutive normal cytology q2-3yrs

Question 22

Recommended age for HPV vaccine

Answer 22

9-26yo

Question 23

Most common cause of dysfunctional bleeding

Answer 23

Anovulation

Question 24

Most common site of endometriosis

Answer 24

Ovaries

Question 25

Most widely accepted theory of endometriosis

Answer 25

Metastatic theory aka Regurgitation/implantation theory Via retrograde menstruation

Question 26

Theory that explains occurrence of endometriosis in the lungs or lymph nodes

Answer 26

Vascular or lymphatic dissemination theory

Question 27

Most common presentation of endometriosis

Answer 27

Infertility

Question 28

Associated with prolonged estrogen stimulation of the endometrium, precursor lesion of endometrial carcinoma

Answer 28

Endometrial hyperplasia

Question 29

Endometrial hyperplasa that invariably leads to endometrial adenocarcinoma

Answer 29

Complex hyperplasia with atypia

Question 30

Most common invasive cancer of the female genital tract

Answer 30

Endometrial carcinoma

Question 31

Most common benign tumor in women

Answer 31

Myoma uteri

Question 32

Central pathologic abnormality is numerous cystic follicles/ follicle cysts (follicular hyperthecosis

Answer 32

PCOS

Question 33

Ovarian tumor with psammoma bodies

Answer 33

Serous tumor

Question 34

Psammoma bodies are found in these pathologic conditions

Answer 34

``` Papillary thyroid ca Meningioma Mesothelioma Prolacitnoma Serous cyst ca (ovary) ``` (MMPS)

Question 35

Rupture of mucinous tumors in the appendix or ovaries causing extensive mucinous ascites,cystic epithelial implants, and adhesions

Answer 35

Pseudomyxima peritoneii

Question 36

Brenner tumor of the ovary

Answer 36

Walthard cell rests

Question 37

Most common ovarian GCT

Answer 37

Mature teratoma aka dermoid cyst

Question 38

Ovary composed entirely of mature thyroid tissue causing hyperthyroidism

Answer 38

Struma ovarii

Question 39

Combination of struma ovarii and carcinoid in the same ovary

Answer 39

Strumal carcinoid

Question 40

Ovarian counterpart of seminoma Usually unilateral with polyhedral cells dispersed in sheet or cords with scant fibrous stroma Malignant Responsive to chemo

Answer 40

Dysgerminoma

Question 41

Presence of schiller duval bodies. Rich in AFP and a1-antitrypsin

Answer 41

Yolk sac tumor

Question 42

``` Elaborates large amount of estrogen Tumor marker (+) inhbin. With Call-Exner Bodies ```

Answer 42

Granulosa cell tumor

Question 43

Tumor that contains sertoli cells or leydig cell interspersed with stroma causing masculinazation/defeminazation

Answer 43

Androblastoma

Question 44

Mucin producing signet ring cancer cells that commonly has gastric origin with bilateral metastases

Answer 44

Krukenberg tumor

Question 45

Most common cause of spontaneous abortion

Answer 45

Chromosomal abnormality

Question 46

Pregnancy loss before 20wks AOG

Answer 46

Spontaneous abortion

Question 47

Most important predisposing condition of ectopic pregnancy

Answer 47

Prior PID

Question 48

Painless vaginal bleeding during 3rd trimester

Answer 48

Placenta previa

Question 49

Painful vaginal bleeding during the 3rd trimester

Answer 49

Placental abruption

Question 50

Karyotype of partial moles

Answer 50

69XXX 69XXY 69XYY (rare)

Question 51

H mole tumor marker

Answer 51

High bHCG for AOG

Question 52

Malignant and rapidly invasive neoplasm of trophoblastic cells

Answer 52

Choriocarcinoma

Question 53

Malignant trophoblastic cells diffusely infiltrating the endomyometrium. High HPL

Answer 53

Placental Site trophoblastic tumor

Question 54

Pus collection within ovary and tubes

Answer 54

Tubo-ovarian abscess