Fast and Slow Muscles, Muscle disorders Flashcards

1
Q

when a motor neuron is excited what fibers contract?

A

all of the fibers in the motor unit contract

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2
Q

how is the force of muscle contraction increased?

A
  • by activating more motor units - recruitment
  • by activating motor units more by increasing stimulus frequency to cause summation or tetanus of individual motor units
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3
Q

what does an EMG (electromyogram) record?

A

it measures the electrical activity of skeletal muscle

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4
Q

What are fast and slow muscles adapted for?

A
  • slow muscles are adapted for slow, sustained, tonic, fatigue-resistant contractions ex) postural muscles
  • fast muscles are adapted for rapid, intense, phasic, easily fatigued contractions ex) gastrocnemius
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5
Q

wat makes a muscle fast or slow?

A

the reason a muscle is fast or slow is simply dependent on the duration of the twitch - the contraction phase and relaxation phase are the start and endpoint of the speed of contraction

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6
Q

are fast and slow metabolism designed for the same metabolism?

A

slow muscles - constantly used so they are adapted for aerobic metabolism - they require lots of ATP

fast muscles are adapted for anaerobic metabolism- they need to twitch quickly they don’t have tim for anaerobic metabolism

*slow muscles are red due to mitochondria, myoglobin, and vascularity where as fast muscles are white due to lack of the above -

*this is why in a chicken, the white meat is found in the chicken wings -b/c they are not used for flight, however the legs are dark meat due to their constant use and presence, therefore, of vasculature/myoglobin/mitochondria

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7
Q

what is the difference between type1, 2a, and 2b muscle fibers?

A

Type1 = small, long twitch with lots of blood supply (slow oxidative fibers)

Type 2a= intermediate - fast twitch but both oxidative and glycolytic - they’re the bets of both worlds … contracts rapidly but is still aerobic (fast oxidative fibers)

Type 2b= Fast contractions, sparse in capillaries, low oxidative capacity - used for short bursts of energy usage - high glycogen capacity though for anaerobic metabolism (fast glycolytic fibers)

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8
Q

do some muscles have all fast or all slow cells?

A

no! the muscles are composed of a mix of cells - it’s the majority of cells that determines if a muscle is fast or slow

ex) soleus muscle is known as a slow muscle, but it has a number of both fast and slow fibers

*individual cells are either fast or slow*

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9
Q

what is the difference in the motorneurons between slow and fast fibers?

A

the motorneurons to slow fibers are smaller than those to fast fibers - their cell bodies are more excitable and are the first to be recruited during moderate contractions - fast fibers will be recruited during more intense contractions

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10
Q

What did the Buller experiment tell us about muscles and nerves?

A

the nerve has a profound influence on our muscle - if you get the fast nerve and stick it into the slow muscle, then the muscle will turn fast - so the nerve determines the type of muscle ( slow or fast)

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11
Q
A
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12
Q

can you train your muscle cells to be fast or slow?

A

no - mainly predetermined

elite sprinters have high numbers of fast fibers =

elite endurance athletes have high numbers of slow fibers

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13
Q

what are fasciculations after denervation?

A

visible twitching caused by release of ACh from degenerating motorneurons -

the nerves start to die after you cut them and they are releasing ACh as a result - therefore they produce a visible contraction as a result of spontaneous ACh release

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14
Q

What can cuase Type 1 and Type 2 atrophy?

A

both of these occur in peripheral neuropathies, disuse (bedrest, spaceflight, immobilization), parkinson’s disease, or myasthenia gravis

mainly type 2 atrophy found with Duchenne muscular dystrophy and ageing (sarcopaenia)

type 2 hypertrophy occurs with weight training

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15
Q

how can we reverse age related sarcopaenia?

A

we can reverse sarcopaenia with weight training

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16
Q

what are the underlying conditions of neuromuscular disease?

A

nueropathy of central or peripheral nervous system

junctionopathy

myopathy