FA, Triglyceride And Cholesterol Sythesis

Question 1

Where is biotin used (key word) what is the key function

Answer 1

Key word = carboxylase

Used with pyruvate carboxylase
Acetyl-CoA carboxylase
Propionyl - CoA carboxylase

Question 2

2 arms of fatty acid synthase

Answer 2

P site - has vitamin B5
SH site (cysteine residue)

Question 3

FAA synthesis vs degradation

Answer 3

Synthesis produces FA from Acetyl CoA

Degradation produces Acetyl CoA from FA

Question 4

What can (and what cannot) be elongated and be desaturated

Answer 4

Fatty Acyl-CoA CAN

FFA cannot

Question 5

Desaturation means to

Answer 5

Add a double bond

Question 6

Sythesis of KB vs Cholesterol

Answer 6

KB HMG CoA synthase is in mito
KB is glucagon induced
KB uses HMG CoA lyase to make the KB

Cholesterol HMG COA sythase is in cytosol
Cholesterol is insulin induced
Cholesterol uses HMG CoA reductase to make the mevalonate

Question 7

Cholesterol —?—->cholesterol ester

And what else do you need

Answer 7

ACAT-acyl CoA cholesterol acyl transferase

Fatty acyl-CoA(not FFA)