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2: NMSP Exam 3 > Extras: Summary Sheets > Flashcards

Extras: Summary Sheets Flashcards

1
Q

sedative drugs major action

A

increase GABA interactions

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2
Q

two benzos for insomnia + their AE

A

temazepam, triazolam; cause anterograde amnesia

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3
Q

what sedative class crosses placenta and causes respiratory depression in fetus + are classic CYP3A4 inducers?

A

barbiturates

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4
Q

barbiturate that treats SZRs

A

phenobarbital

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5
Q

issue with ramelteon

A

<50% of pts see results

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6
Q

issue with suvorexant

A

next-day somnolence, some complex sleep behaviors

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7
Q

which sedative is only for sleep maintenance issues, not sleep onset issues?

A

doxepin

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8
Q

four classes of opioids

A
  1. phenylpiperidines
  2. diphenylheptanes
  3. phenanthrenes
  4. benzomorphans
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9
Q

loperamide targets what receptors?

A

mu opioid receptors in GI tract

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10
Q

four opioid partial agonists

A
  1. pentazocine
  2. buprenorphine
  3. nalbuphine
  4. butorphanol
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11
Q

pentazocine use

A

pre-op supplement to anesthesia

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12
Q

what strucutral class are naloxone and naltrexone?

A

phenanthrenes

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13
Q

naltrexone has highest affinity at what receptor?

A

mu opioid receptor

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14
Q

scheduled drugs: which one is the worst vs the most chill?

A

schedule I is worst (no medical use, just recreational drug with high abuse potential), schedule 4 is the mildest

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15
Q

two SSRIs with a second function of being partial/full agonists to the 5HT receptors

A

Vilazodone, Vortioxetine

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16
Q

what SSRI is most anti-cholinergic of the group and what does that mean for its use?

A

Paroxetene -> dont give to elderly pts

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17
Q

what SNRI also has actions on DA, making it an anti-psychotic?

A

amoxapine

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18
Q

3 C’s of TCA OD

A

coma, convulsions, conduction abnlts

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19
Q

TCAs are SNRI’s that also affect what other three receptors?

A

Histamine, muscarinic, a1 adrenergic

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20
Q

three receptors blocked by SARAs

A

a1 adrenergics, 5HT, H1

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21
Q

major AE of SARAs

A

sedation

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22
Q

which SARA causes hepatic toxicity

A

Nefazodone

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23
Q

which drug class causes hypertensive crisis and why

A

MAOIs: block MAO A -> tyramine cant be broken down -> tyramine causes catecholamine release -> HTN

24
Q

what drug type is Buproprion

25
Q

what does Esketamine do?

A

NMDA receptor antagonist

26
Q

one drug specifically for post-partum depression

A

Brexanolone

27
Q

mnemonic for anti-depressant withdrawal

A

FINISH: flu-like, insomnia, nausea, imbalance, sensory sx (parasthesias), hyperarousal

28
Q

which bipolar drug is only used for maintenance, not acute mania?

A

lamotrigine

29
Q

which AED for bipolar induces hepatic UGT while the other ones inhibit it?

A

Carbamazepine

30
Q

amphetamine-based stimulants: liquid, IR vs ER drug

A

liquid IR: Detroamphetamine sulfate

liquid ER: amphetamine

31
Q

amphetamine based stimulant that is ER & ODT

32
Q

Daytrana patch is what drug?

A

methylphenidate

33
Q

two AEs with atomoxetine

A

liver injury, SI**

34
Q

atomoxetine vs guanfacine & clonidine MOAs

A
  1. atomoxetine: inhibits NE reuptake

2. guanfacine/clonidine: a2 adrenergic agonists in PFC

35
Q

two withdrawals that can be deadly

A

alcohol, barbiturates/sedatives

36
Q

treating HTN and hyperthermia in a pt on meth or coke

A

phentolamine

37
Q

MOA of cocaine

A

inhibits DA reuptake

38
Q

drug for pt on LSD or PCP

39
Q

only rec drug where pupils are constricted with use

A

opioids / heroin

40
Q

treating HTN in a pt in opioid withdrawal

41
Q

acamprosate MOA

A

NMDA antag + GABA R agonist

42
Q

FGAs vs SGAs MOA

A
  1. FGA: D2 R blocker

2. SGA: block 5HT > D2

43
Q

which FGA causes torsades de pointes

A

Thioridazine

44
Q

what drug class can cause NMS (neuroleptic malignant syndrome)

45
Q

two SGAs notable for prolactin sx

A

iloperidone, risperidone

46
Q

SGA notable for QT prolongation/EKG changes

A

Ziprasidone

47
Q

two SGAs notable for WG, glucose/lipid increase

A

Clozapine, Olanzapine

48
Q

SGA specifically for Parkinson’s psychosis

A

Pimavanserin

49
Q

three drugs to treat dystonia from anti-psychotics***

A

Benztropine, Benadryl, Triheyxphenidyl

50
Q

three drugs to treat akathisia from anti-pschotics

A

BB (propanolol), Benzodiazepine, Benztropine

51
Q

two drugs to treat parkinsonism from anti-psychotics

A

benztropine, amantidine

52
Q

drug type that treats tardive dyskinesia from anti-psychotics, + two examples

A

VMAT2 inhibitors; Valbenazine & Deutetrabenazine

53
Q

anti-psychotics: 4 for acute agitaiton + 4 for long acting injectables

A
  1. Acute: HOAZ: Haloperidol, Olanzapine, Aripiprazole, Ziprasidone
  2. Long-Acting: ROAP: Risperidone, Olanzapine, Aripiprazole, Paliperidone
54
Q

what drug type to avoid in elderly hospitalized pts to avoid delirium

55
Q

two types of ADHD

A

inattentive type, hyperactive type

2: NMSP Exam 3 (20 decks)

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