44: Anti-Psychotics

Question 1

Uses for anti-psychotics

Answer 1

schizophrenia, bipolar, major depressive DO, tourette’s, irritability with autism spectrum disorders, acute agitation

Question 2

positive sx of schizophrenia

Answer 2

hallucinations, delusions, disorganized speech/thought, agitation, abnormal motor behavior

Question 3

negative sx of schizphrenia

Answer 3

apathy, avolition, alogia, cognitive defects, social withdrawal

Question 4

hyperprolactinemia symptoms**

Answer 4

amenorrhea, galactorrhea, gynecomastia, decreased libido

Question 5

what baseline values should you get from a pt starting anti-psychotics?

Answer 5

BMI, weight, fasting plasma glucose, lipids, BP

Question 6

two SGAs with the least amount of side effects

Answer 6

aripiprazole, lumateperone

Question 7

two SGAs with the largest amount of side effects

Answer 7

Clozapine, olanzapine

Question 8

four scales to monitor anti-psychotics

Answer 8

GASS, AIMS, BARS, ESRS

Question 9

GASS stands for?

Answer 9

Glascow ANti-psychotic side effect scale

Question 10

AIMS stands for?

Answer 10

abnormal involuntary movement scale

Question 11

treatment for NMS (neuroleptic malignant syndrome)***

Answer 11

Dantrolene

Question 12

acute dystonic reactions

Answer 12

sudden tonic contractions of muscles of tongue, neck, back, mouth, eyes

Question 13

akathisia

Answer 13

motor restlessness, may involve entire body (pacing, cant keep feet still)

Question 14

anti-psychotic induced catatonia

Answer 14

withdrawal, mutism, motor abnormalities (rigidity, immobility, waxy flexibility)

Question 15

tardive dyskinesia

Answer 15

fasciculations of tongue, lingual-facial hyperkinesias, choreoathetotic movements of extremities and trunk