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2: GI2 Exam 1 > Extras: Diarrhea And Constipation Drugs > Flashcards

Extras: Diarrhea And Constipation Drugs Flashcards

1
Q

3 Opioid agonists + 3 antagonists

A

Agonists: loperamide, eluxadoline, diphenoxylate
Antagonists: methylnaltrexone, alvimopan, naloxegol

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2
Q

Two meds for IBS-D and three for IBS-C

A

IBS-D: eluxadoline, alosetron

IBS-C: linaclotide, lubiprostone, tegaserod

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3
Q

Serotonin antagonist for diarrhea

A

Alosetron

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4
Q

Alosetron major side effect

A

Ischemic colitis

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5
Q

One Cl channel inhibitor vs one Cl channel activator

A

Inhib: crofelemer
Activator: lubiprostone

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6
Q

Major use for crofelemer

A

Non-infectious diarrhea in HIV pts on ART

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7
Q

Two drug classes for opioid induced constipation

A
  1. Peripheral opioid antagonists

2. Cl channel activators

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8
Q

Drug only used for preventing post-op ileus

A

Alvimopan

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9
Q

Risk of alvimopan

A

MI’s when using 15+ doses

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10
Q

What receptor do peripheral opioid antagonists work on

A

Mu

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11
Q

Two drug classes for chronic idiopathic constipation

A
  1. Guanylate cyclase C agonsists

2. Cl channel activators

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12
Q

One guanylate cyclase C agonist

A

Linaclotide

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13
Q

One Cl channel activator

A

Lubiprostone

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14
Q

One 5HT4 receptor partial agonist

A

Tegaserod

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15
Q

Four bulk forming agents

A
  1. Food
  2. Psyllium
  3. Methylcellulose
  4. Ca polycarbophil
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16
Q

Two stool softeners

A
  1. Decussate

2. Mineral oil

17
Q

Three laxative classes that can cause electrolyte disturbances

A
  1. Salines
  2. Osmotics
  3. Stimulants
18
Q

Four osmotics

A
  1. Lactulose
  2. Lacitol
  3. Polyethylene glycol
  4. Sorbitol
19
Q

Drug for liver dz pts with hyperammonemia

A

Lactulose

20
Q

Three drugs used for colonoscopy prep

A
  1. 3 salines together
  2. PEG3350
  3. Na picosulfate
21
Q

Four stimulants

A
  1. Bisacodyl
  2. Glycerin
  3. Senna
  4. Na picosulfate
22
Q

Senna side effect

A

Urine discoloration -> Brown/pink/red

2: GI2 Exam 1 (24 decks)

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