Extra eukaryotic stuff Flashcards
Look at size of mouse egg and human egg
same size produce different size animal
what does the size of the organism depend on
Total cell mass
What determines the total cell mass to determine size of organism
number and size of cells
what determines the cell number
cell death and cell division
what determines organ and body size
Cell growth
Cell division
Cell survival
what are cell growth, division and death regulated by
intracellular and extracellular programs
What do extracellular signal molecules do
Regulate cell growth, division, and survival
what are extracellular signal molecules
Usually soluble secreted proteins,
proteins bound to cell surface, or
ECM components
3 major classes of extracellular signal molecules
Mitogens
Growth factors
Survival factors
Mitogen (extracellular signal molecule)
stimulates cell division
triggers G1/S-cdk activity
Growth factors (extracellular molecule)
stimulate cell growth
increase cell mass
promote protein synthesis
inhibit protein degradation
Survival factors (extracellular signal molecule)
promote cell survival
suppress programmed cell death
what is programed cell death
apoptosis
Mitogens
stimulates cell division
look at slide 35 for observation on this
with platelets
Platelet-derived growth factor (PDGF)
mitogen
helps stimulate cell division during healing
