Excretion Flashcards

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1
Q

What is metabolism?

A

All the chemical reactions that happen in your cells

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2
Q

Why can’t waste products build up in the body?

A

They are toxic and would cause damage by affecting other metabolic reactions

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3
Q

What is excretion?

A

The removal of the waste products of metabolism from the body

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4
Q

What is broken down by the liver?

A

Excess amino acids

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5
Q

Why do excess amino acids need to be broken down?

A

Amino acids contain nitrogen and nitrogen can’t be stored in the body so they are broken down to prevent damage to the body

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6
Q

What occurs in deamination?

A

Nitrogen containing amino groups (-NH2) removed from excess amino acids - forming ammonia (NH3) and organic acids

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7
Q

Why can’t ammonia be excreted directly? How is it excreted?

A

It is too toxic to be excreted directly, so it is combined with CO2 in the ornithine cycle to create urea

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8
Q

Where in the body is ammonia combined with CO2 in the ornithine cycle?

A

The mitochondria of the liver cells

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9
Q

What is alcohol broken down into and where?

A

Ethanol is broken down by the liver into ethanal

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10
Q

What are the four substances broken down by the liver?

A

1)excess amino acids
2) alcohol
3) paracetamol
4) insulin

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11
Q

What part supplies the liver with oxygenated blood from the heart?

A

The hepatic artery

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12
Q

What part takes deoxygenated blood away from the liver?

A

The hepatic vein

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13
Q

What part brings blood from the small intestine, and why?

A

The hepatic portal vein - it is rich in the products of digestion (no harmful substances also)

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14
Q

Where does the bile duct take bile to?

A

The gallbladder to be stored

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15
Q

What is the liver made up of?

A

Liver lobules - cylindrical structures made of cells called hepatocytes

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16
Q

What is in the middle of each lobule in the liver?

A

Central vein that connects to the hepatic vein

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17
Q

What are sinusoids in the liver?

A

Capillaries in which blood runs through past hepatocytes that remove the harmful substances and oxygen

18
Q

What are the two parts of the liver in which blood runs through that join at the sinusoid to the central vein?

A

The hepatic artery and the hepatic portal vein

19
Q

What do kupffer cells do and where are they located?

A

They removed bacteria and breakdown old red blood cells - connected to the walls of the sinusoids

20
Q

What do hepatocytes produce and where does this go?

A

They produce bile and secreted into the bile canaliculi which drains to the bile ducts

21
Q

Under a light microscope, what does the central vein of the liver look like?

A

A large white circular shape

22
Q

Under a light microscope, what do hepatocytes in the liver look like?

A

The largest mass with red nuclei

23
Q

Under a light microscope, what do sinusoids in the liver look like?

A

Other white spaces that aren’t the central vein

24
Q

What are the two main function of the kidney?

A

To excrete waste products and regulate water potential of the blood

25
Q

Where does blood enter the kidney?

A

The renal artery

26
Q

Upon entering the kidney, where does the blood go and what happens to it?

A

The blood passes through the capillaries and substances are filtered out of the blood

27
Q

What is the name of the process where substances are filtered out of the blood in the kidneys?

A

Ultrafiltration

28
Q

What is reabsorbed back into the blood from the kidney and why?

A

Glucose because it is useful

29
Q

Where do the unwanted substances from ultrafiltration go?

A

Ureter and the bladder to be expelled as urine

30
Q

Once the blood from the kidney has undergone ultrafiltration, where does it go?

A

Out the kidneys through the renal vein

31
Q

Where does ultrafiltration take place?

A

The glomerulus that is looped inside the bowmans capsule

32
Q

How do substances move from the capillary into the Bowman capsule?

A

High pressure forces liquid and small molecules out the blood

33
Q

What are the names of the arterioles before and after the blood enters the glomerulus?

A

The afferent arterioles and the efferent arteriole

34
Q

Once the substances have entered the Bowman capsule, what path do they travel down?

A

Through proximal convoluted tubule, the loop of henle and the distal convoluted tubule to the renal vein that heads to the ureter

35
Q

Why can’t larger molecules pass through into the Bowman capsule?

A

They are too big to pass through the pores in the endothelium

36
Q

What takes place as the filtrate flows along the PCT, loop of Henle and the DCT?

A

Selective reabsorption

37
Q

What is reabsorbed by the PCT?

A

Useful solutes (glucose, amino acids and vitamins)

38
Q

What is urine usually made up of?

A

Water, urea and hormones

39
Q

What doesn’t urine usually contain?

A

Proteins, blood cells, glucose and amino acids

40
Q

What does the cortex of a nephron look like under a light microscope?

A

A glomerulus surrounded by a white Bowman capsule which is surrounded by squamous epithelial cells

41
Q

What are the long white lines on a nephron under a light microscope?

A

Loops of henle