Excitable Tissues/Neuron signalling part 3 Flashcards

1
Q

Which is more water-soluble or fat-soluble?
hydrophilic or lipophilic hormones

A

Hydrophilic is water-soluble
Lipophilic fat-soluble

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Estrogen and insulin are examples of which chemical messenger in the body?

A

Hormones

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Which chemical messenger is secreted by the endocrine gland and must be near a blood vessel?

A

Hormones

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

The difference in charge from the ICF to the ECF is called?

A

Membrane potential

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

The neurocrine that release hormones into the bloodstream. travel thru the blood to reach their target cells or organs and they bind to specific receptors, What are they called?

A

Neurohormone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

The type of neurocrine that reaches the brain to send a message and act in a much longer time than the neurotransmitters are called?

A

Neuromodulators (neuropeptides)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Which chemical messenger is secreted by a nerve cell?

A

Neurocrine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

The type of neurocrine secretion that is very rapid/fast and it secretes to a target cell (muscle)?

A

Neurotransmitter

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

The chemical messenger that activates the same cell that creates it (self exciting)

A

Autocrine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

The chemical messenger secreted by one cell but excites neighboring cells is called?

A

Paracrine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Immune response
Fever production
Embryo development
inflammatory response
are all associated with which type of chemical messenger?

A

Cytokines

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Fever is spread by

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is Erythropoietin?

A

used for Red blood cell production

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Interleukin-1 (IL-1) and Erythropoietin are examples of this type of chemical messenger?

A

Cytokines

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Cholecystokinin CCK is an example of this type of chemical messenger. it reaches the brain and satiety center

A

Neuromodulator

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Acetylcholine is an example of what type of chemical messenger

A

Neurotransmitters

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Histamine is an example of what type of chemical messenger

A

Autocrine and Paracrine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

5 types of chemical messengers are

A
  1. autocrine
  2. paracrine
  3. neurocrine
  4. hormone
  5. cytokines
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Tetanus toxin blocks inhibitory impulses while leaving excitatory inputs unchecked.
true or false

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Tetanus toxin prevents the release of

A

inhibitory neurotransmitter GABA affecting skeletal muscles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Tetanus toxin gives rise to lockjaw (also known as trismus)
True or false

A

true

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

When Levodopa crosses _________ and is converted into dopamine.

A

BBB blood-brain barrier.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What drug is used in the Treatment of Parkinson’s disease?

A

Levodopa

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Parkinson’s disease is a result of dopamine deficiency in what region?

A

Basal Nuclei

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
The region of the Brain involved in controlling complex movement?
Basal nuclei
18
Cocaine blocks the reuptake of neurotransmitters/dopamine in the brain T or F
True
19
Cocaine causes the accumulation of dopamine in the
Synaptic cleft
19
Parkinson's disease is a result of a deficiency of __________ in the basal nuclei.
Dopamine
20
Drugs/disease/infection that alter synaptic transmission
1. cocaine 2. Parkinson's disease 3. Tetanus toxin
21
if EX1 is stimulated a second time after the first one has died off and does not reach the threshold what is the result?
No summation
22
When excitatory and Inhibitory synapses are activated simultaneously what is the result?
they cancel each other out
23
EX.1 + EX.2 when 2 or more EPSPs are initiated simultaneously it brings the cell to the threshold that results in
Spatial summation
24
EX.1 + EX.1 if EX.1 is stimulated a second time before the first EPSP dies off, the second EPSP will add onto the first one which brings the postsynaptic cell to threshold and results in
Temporal summation
25
What is the neural summation?
when you add up EPSP and IPSP excitatory and inhibitory post-synaptic potential at the same time.
26
Neural summation produces
GPSP - grand postsynaptic potential
27
Which synapse makes the cell not reach a threshold?
Inhibitory post-synaptic potential (IPSP)
28
which synapse causes a chloride influx making it more negative
Inhibitory post-synaptic potential (IPSP)
29
which synapse causes leakage of K (K efflux) out of the neuron
inhibitory post-synaptic potential
30
which synapse causes depolarization in the post-synaptic neuron?
excitatory post-synaptic potential
31
which synapse excites the next neuron and causes sodium channels to open
excitatory post-synaptic potential
32
which synapse keeps the msg going
excitatory post-synaptic potential
33
which synapse becomes more hyperpolarized inhibitory or excitatory?
inhibitory post-synaptic potential
34
Which synapses keep going toward the threshold?
excitatory post-synaptic potential
35
Two types of synapses
excitatory and inhibitory
36
When an action potential reaches the axon terminal, it causes these calcium channels to open. This influx of calcium ions into the axon terminal triggers the release of _________ from ________ into the _______
Neurotransmitters synaptic vesicles ...into the...... synaptic cleft,
37
Axon terminals contain chemically-gated calcium channels True or False
True
38
Neurotransmitters then bind to receptors in
postsynaptic neuron
39
Synaptic vesicles with neurotransmitters are released by _____________
Exocytosis
40
a neuron whose action potentials are propagated away from the synapse is?
postsynaptic neuron
41
Which neuron receives the msg?
postsynaptic neuron
42
Space between the presynaptic neuron and the post-synaptic neuron is called
synaptic cleft
43
What immediately mobilizes the neuron to open the synaptic vesicles and enter the synaptic cleft
Neurotransmitter
44
Neurotransmitters are released through
exocytosis
45
what stores neurotransmitters?
Synaptic vesicles
46
What opens on the presynaptic neuron and becomes calcium channels, calcium gets in and floods the axon terminal.
synaptic knob
47
What contains synaptic vesicles?
synaptic knob
48
The neuron that brings the message (passing it to another neuron) and it's before the junction is called what?
presynaptic neuron
49
Junctions with other neurons are called
synapse
50
What are synapses?
Junctions with other neurons.
51
what are the causes of multiple sclerosis?
- Herpes #6 infection - Environmental (causing myelin to be lost) - Herpes #4 (EBV virus)
52
What is the demyelination of the neuron?
It's a Demyelinating disease Examples: 1. Multiple sclerosis (patients lose myelin) 2. Loss of vision (early onset or late) 3. Muscle weakness, wheelchair-bound 4. skeletal muscles that are supposed to be myelinated are failing