Exam III practice questions Flashcards
Name a non-collagenous protein associated with bone:
osteonectin, osteopontin, osteocalcin, sialoprotein, phosphoprotein, glycoprotein, bone specific protein, bone morphogenetic protein, carboxyglutamic acid containing protein
According to your text, which bone morphogenic proteins promote bone formation?
BMP 2, 4, 6 and 7
(if only one BMP can be chosen pick BMP2)
What compounds are found in bone matrix vesicles?
alkaline phosphatase, pyrophosphatase, glycoprotein, phosphoproteins, and phospholipids
A ____ is defined as a denuded area of bone that extends through the marginal bone creating a “cleft-like” defect
dehiscence
Multiple myeloma accounts for nearly ____ % of all malignancies involving bone
50%
According to your text, the intrinsic fibers of alveolar bone are oriented ____ to the bone surface; the extrinsic fibers of the PDL are oriented ____ to the bone surface
intrinsic= parallel
extrinsic = perpindicular
Normally, at 4-5 years of age, the jaws will accomodate a total of ___ erupted and unerupted teethteeth
20 erupted + 28 developing (unerupted) teeth= 48 teeth total
What is the rate of eruption of teeth:
3mm every 3 months but this is NOT a constant rate
The deciduous dentition has generally completed eruption by age:
3 years
Melanocytes are derived from cells of what embryonic structure:
neural crest
After root formation is complete, the reduced enamel epithelium forms the ____ after eruption
junctional epithelium
What is the most common neoplastic (cancerous) lesion arising from odontogenic epithelium?
ameloblastoma
Oral cancer accounts for approximately ___ % of all cancers
3 %
The highest incidence of squamous cell carcinoma is found in what population?
Middle-Aged African-American
According to your text, where are oxytalan fibers found?
Periodontal ligament
Oral cancer accounts for approximately ___% of all cancers
3%
Short columnar/tall cuboidal epithelial cells are are found in which ducts?
striated ducts
What is the classification of the submandibular gland?
Mixed seromucous gland (predominately serous with mucous contributions)
What is the terminal exretory duct of the submandibular gland?
Wharton’s duct
Pleomorphic adenoma is a benign tumor that accounts for ___% of parotid salivary gland tumors
53-77%
According to your text, on the posterior slope of the TMJ articular eminence, the inner perpendicular collagen fibers are responsible for ____.
resting compression of mandibular condyle against the articular surface
In the intimal layer of the TMJ, the macrophage-like cells are the:
Type A cells
The type B synovial cells of the synovial membrane secrete:
hyaluronate
Which receptors are found in the TMJ area?
A: Ruffini Corpuscles- proprioception
B: Pacinian Corpuscles- dynamic mechanoreception
C: Golgi Tendon Organs- static mechanoreception
D: Free Nerve Endings- pain
2- What is the fibrillar component of the mature dentin matrix?
Type 1 collagen
2- Histologically, the presence of ____ is used to distinguish between the root dentin from the crown dentin
Tome’s Granular layer
2- According to your text, when compared to intertubular dentin, how is peritubular dentin characterized?
It has a greater content of inorganic salts, more mineralized because exposed to more granular stuff
2- During the transition from undifferentiated cell to mature odontoblast, what is the function of fibronectin?
Help align themselves along the basal lamina, assume polarity and differentiate into secretory cells
2- What is contained in the odontoblastic matrix vesicle?
Alkaline phosphatase, phospholipids, phosphoproteins, pyrophosphatase, Ca2+, PO4-, annexin, and calcium hydroxyapatite crystallites
2- What growth factors are secreted by IEE during initiation of odontoblastic differentiation?
- transforming growth factor (TGF)
- Fibroblast growth factor (FGF)
- Insulin-like growth factor (IGF)
- Bone morphogenetic protein (BMP)
2- What is the function of Annexin V in odontoblastic matrix vesicles?
Mediates flow of calcium into the matrix vesicle; also serves as a collagen receptors that binds matrix vesicles to collagen
2- The theory most commonly accepted to explain why pain is elicited when dentin is mechanically stimulated is the ____ theory
Brannstrom’s Hydrodynamic Theory
2- In the dental pulp, macrophages and dendritic cells constitute ____% of the total cell population
8%
2- The cells responsible for physiologic matrix of the cementum surface and alveolar bone proper are derived from undifferentiated cells located in the:
interstitial spaces of the PDL