Exam 5 - Malaria Gardner Flashcards
atovaquone/proguanil chemoprophylaxis duration
Begin 1-2 days before departure and continue for 7 days after leaving endemic area
chloroquine/hydroxychloroquine chemoprophylaxis duration
Begin 1-2 WEEKS before departure and continue for 4 WEEKS after leaving endemic area
doxycycline chemoprophylaxis duration
Begin 1-2 DAYS before departure and continue for 4 WEEKS after leaving endemic area
mefloquine chemoprophylaxis duration
Begin at least 2 WEEKS before departure and continue for 4 WEEKS after leaving endemic area
primaquine chemoprophylaxis duration
Begin 1-2 DAYS before departure and continue for 7 DAYS after leaving endemic area
tafenoquine chemoprophylaxis duration
Begin 3 DAYS before departure and continue for 1 WEEK after leaving endemic area
atovaquone/proguanil is CI in CrCL < ____ mL/min
a. 30
b. 50
c. 90
d. 120
a. 30
Begin 1-2 DAYS before departure and continue for 7 DAYS after leaving endemic area. SELECT ALL THAT APPLY (2)
a. atovaquone/proguanil
b. chloroquine and hydroxychloroquine
c. doxycycline
d. mefloquine
e. primaquine
f. tafenoquine
a. atovaquone/proguanil
e. primaquine
Begin 1-2 WEEKS before departure and continue for 4 WEEKS after leaving endemic area
a. atovaquone/proguanil
b. chloroquine and hydroxychloroquine
c. doxycycline
d. mefloquine
e. primaquine
f. tafenoquine
b. chloroquine and hydroxychloroquine
Begin 1-2 DAYS before departure and continue for 4 WEEKS after leaving endemic area
a. atovaquone/proguanil
b. chloroquine and hydroxychloroquine
c. doxycycline
d. mefloquine
e. primaquine
f. tafenoquine
c. doxycycline
Begin at least 2 WEEKS before departure and continue for 4 WEEKS after leaving endemic area
a. atovaquone/proguanil
b. chloroquine and hydroxychloroquine
c. doxycycline
d. mefloquine
e. primaquine
f. tafenoquine
d. mefloquine
Begin 3 DAYS before departure and continue for 1 WEEK after leaving endemic area
a. atovaquone/proguanil
b. chloroquine and hydroxychloroquine
c. doxycycline
d. mefloquine
e. primaquine
f. tafenoquine
f. tafenoquine
which antimalarial is NOT dosed once weekly?
a. primaquine
b. chloroquine
c. hydroxychloroquine
d. mefloquine
a. primaquine
(this one is once daily)
which of the following CANNOT be used in all malaria-endemic regions?
a. atovaquone/proguanil
b. doxycycline
c. mefloquine
d. tafenoquine
c. mefloquine
antimalarial DOC for regions primarily with P. vivax
a. hydroxychloroquine
b. mefloquine
c. clindamycin
d. primaquine
d. primaquine
T or F: atovaquone/proguanil can be used in pregnancy
F
which antimalarial drug should be avoided in women prone to vaginal yeast infections?
a. atovaquone/proguanil
b. chloroquine and hydroxychloroquine
c. doxycycline
d. mefloquine
e. primaquine
f. tafenoquine
c. doxycycline
which drug should be avoided in depression, hx of psychiatric disorders or seizures, and cardiac conduction abnormalities?
a. atovaquone/proguanil
b. chloroquine and hydroxychloroquine
c. doxycycline
d. mefloquine
e. primaquine
f. tafenoquine
d. mefloquine
which drug should be avoided in psychotic disorders?
a. atovaquone/proguanil
b. chloroquine and hydroxychloroquine
c. doxycycline
d. mefloquine
e. primaquine
f. tafenoquine
f. tafenoquine
which of the following requires G6PD testing? SELECT ALL THAT APPLY (2)
a. atovaquone/proguanil
b. chloroquine and hydroxychloroquine
c. doxycycline
d. mefloquine
e. primaquine
f. tafenoquine
e. primaquine
f. tafenoquine
we consider a pt might have malaria if they meet what two criteria?
fever AND has traveled to a malaria endemic region before fever onset
symptom onset for malaria: typically ____-____ weeks after mosquito bite and can occur up to ____ years after exposure to P. vivax or P. ovale
2-4 weeks; 3 years
standard for malaria diagnosis
Giemsa-stained blood smear
for severe malaria, pts must meet at least one criteria of: (8 things)
-Impaired consciousness/coma
-Hemoglobin < 7 g/dL
-Acute kidney injury
-Acute respiratory distress syndrome (ARDS)
-Circulatory collapse/shock
-Acidosis
-Disseminated intravascular coagulation
-Parasite density of ≥ 5%
