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PHRM 865 Therapeutics > Exam 1 - Random Info ID > Flashcards

Exam 1 - Random Info ID Flashcards

1
Q

Gram Positive Cocci (5)

A

LoVE is Positive

Lactococci
Viridians
Enterococci
StaPhylococci
StrePtococci

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2
Q

Gram Negative Cocci

A

Neisseria

Ne -> negative
ss -> double letter like cc

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3
Q

Gram Positive Bacilli (5)

A

Cute Lady named ABC is positive

Clostridium
Listeria
Actinomyces
Bacillus
Corynebacterium

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4
Q

Gram Negative Bacilli common ending

A

-ella

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5
Q

Gram Negative Bacilli story (8 of them)

A

a guY took a Helicopter to the Camp, drank contaminated water, had traveler’s diarrhea, was injured on the way to the hospital with blood. Pseudo: false/negative

Yersinia
Helicobacter
Campylobacter
E. Coli
Vibrio cholera
Bacteroides
Haemophilus
Pseudomonas

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6
Q

gram positive

a. dark purple
b. light pink

A

a. dark purple

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7
Q

gram negative

a. dark purple
b. light pink

A

b. light pink

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8
Q

which antibiotic does NOT inhibit cell wall synthesis?

a. penicillin
b. cephalexin
c. imipenem
d. doxycycline
e. vancomycin

A

d. doxycycline

(blocks protein synthesis)

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9
Q

which of the following does NOT work by inhibiting cell wall synthesis?

a. amoxicillin
b. levofloxacin
c. aztreonam
d. vancomycin
e. cefipime

A

b. levofloxacin

(fluoroquinolones inhibit DNA synthesis)

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10
Q

which antibiotic binds to the 50S ribosomal subunit?

a. azithromycin
b. gentamicin
c. doxycycline
d. tobramycin

A

a. azithromycin

(binds to 23S, which is part of 50S)

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11
Q

macrolides drug name ending

A

-thromycin

(aminoglycosides end in -mycin)

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12
Q

aminoglycosides drug name ending

A

-mycin or -micin

(macrolides end in -ithromycin)

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13
Q

which TWO antibiotic classes bind to the 30S ribosomal subunit to inhibit protein synthesis?

a. aminoglycosides
b. fluoroquinolones
c. streptogramins
d. cephalosporins
e. tetracyclines

A

a. aminoglycosides
e. tetracyclines

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14
Q

tetracyclines are generally:

a. bacteriostatic
b. bactericidal
c. neither
d. both

A

a. bacteriostatic

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15
Q

which antibiotic binds to the 50S ribosomal subunit to inhibit protein synthesis?

a. minocycline
b. tobramycin
c. chloramphenicol
d. gentamicin
e. ceftazidime

A

c. chloramphenicol

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16
Q

2 beta-lactamase-resistant parenteral penicillins

A

methicillin
nafcillin

17
Q

2 beta-lactamase-sensitive, broad-spectrum, oral penicillins

A

ampicillin
amoxicillin

18
Q

which antibiotic binds to the 50S ribosomal subunit to inhibit protein synthesis?

a. clindamycin
b. demeclocycline
c. vancomcyin
d. dicloxacillin
e. ciprofloxacin

A

a. clindamycin

19
Q

which antibiotic is generally considered bacteriostatic?

a. vancomycin
b. doxycycline
c. cephalexin
d. nafcillin

A

b. doxycycline

20
Q

which antibiotic is generally considered bacteriostatic, but bactericidal at high doses?

a. cefazolin
b. gentamicin
c. amoxicillin
d. clarithromycin

A

d. clarithromycin

21
Q

which antibiotic binds to 23S and 50S and prevents formation of initiation complex?

a. chloramphenicol
b. imipenem
c. minocycline
d. vancomycin
e. linezolid

A

e. linezolid

22
Q

which antibiotic works by inhibiting DNA synthesis?

a. synercid
b. levofloxacin
c. aztreonam
d. cephalexin
e. doxycycline

A

b. levofloxacin

23
Q

3 beta-lactamase resistant, oral penicillins

A

OCD

oxacillin
cloxacillin
dicloxacillin

24
Q

which antibiotic causes a frameshift mutation?

a. demeclocycline
b. methicillin
c. ceftazidime
d. neomycin

A

d. neomycin (aminoglycosides)

25
Q

antibiotic that blocks and inhibits ribosome tunnel?

a. streptomycin
b. dalfopristin
c. quinupristin
d. linezolid

A

c. quinupristin

26
Q

aztreonam has a C-2 ______ ______ group

a. sulfamic acid
b. secondary hydroxyl
c. tertiary hydroxyl
d. piperazine ring

A

a. sulfamic acid

27
Q

resistance for linezolid

A

G2576U substitution

28
Q

linezolid metabolism

A

morpholine ring oxidation

29
Q

aminoglycosides are used against:

a. mainly gram positive
b. mainly gram negative

A

b. mainly gram negative

30
Q

macrolides are used against:

a. mainly gram positive
b. mainly gram negative

A

a. mainly gram positive

31
Q

aztreonam use

a. gram positive
b. gram negative

A

b. gram negative

32
Q

vancomycin use

a. gram positive
b. gram negative

A

a. gram positive

33
Q

which antibiotic interacts with MAOI’s and has a SE of thrush?

A

linezolid

34
Q

________ and ________ have intrinsic resistance to macrolides (blanks are bugs)

A

pseudomonas
enterococcus

35
Q

what is the SE of using sarecycline with oral retinoids?

A

inc ICP

36
Q

which antibiotic class inhibits CYP3A4?

a. macrolides
b. fluoroquinolones
c. aminoglycosides
d. linezolid

A

a. macrolides

37
Q

first gen quinolones work against gram ______ bacteria, as the gen goes up they have better activity against gram _____ bacteria

A

negative
positive

38
Q

3 tetracyclines that lack C-6 hydroxyl

A

DMT

doxycycline
minocycline
tigecycline

PHRM 865 Therapeutics (8 decks)

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