Exam 4 Tremors Flashcards
Essential Tremor is?
Auto-dominant: FET1/EMT1 or FET2/EMT2
Disruption of cerebellar outflow
Essential Tremor presentation? (5)
Postural or kinetic U upper extrem Resting tremor later P improvement w/ EtOH P head/chin/voice tremors
Essential Tremor tx? (4)
Wrist weights
Propranolol
Primidone, Gabapentin (anticonvulsant)
Botox for head
Restless Leg (Ekbom Dz) is? (3)
Abn urge to move legs when at rest
Alleviated by mvmt
Worse at night
Restless Leg (Ekbom Dz) 2° causes? (4)
Neuropathy
Fe deficiency
Preggo
Renal fail
Restless Leg tx? (5)
Only in p.m. Fe DA agonists Anti-epileptics BZs
Chorea: Hereditary causes? (3)
Huntington Disease
Neuroacanthocytosis
Sickle Cell Anemia
Chorea: Metabolic causes? (2)
Wilson’s (copper)
Porphyria (heme disorder)
Chorea: Drug causes? (6)
Parkinson's meds Anti-epileptics Cocaine TCAs OCPs Li+
Chorea: Systemic causes? (4)
Hyperthyroid
Hypoparathyroid
SLE
Hyper or hypoNa+/Ca2+/Mg/Glucose
Chorea: Infectious causes? (3)
Sydenam’s (rheumatic fever)
TB
AIDS
Huntington’s Dz is?
Auto-dom tri repeat
Huntington’s Dz: Motor sxs? (5)
Chorea Dystonia Brady Dysarthria Wide gait
Huntington’s Dz: Cognitive sxs? (2)
Executive fxn
Visual-spacial
Huntington’s Dz: Psych sxs? (3)
Depression
Mania
Psychosis
Huntington’s Dz: Progress?
Onset 35-40 yo
Time till death ~ 15 yrs
Huntington’s Dz: Tx? (3)
Anti-DA
BZs
Antidepress
Huntington’s Dz: Juvenile?
Onset < 20 yo
From father
Akinetic-rigid phenotype
Tics are?
Simple? (3)
Complex? (3)
Semi-voluntary, suppressible
Motor or phonic
Simple: sniff, grunt, blink
Complex: words, chew, scratch
Tourette’s criteria? (4)
Motor and phonic for > 1yr
Onset < 18yo
No 2° cause
Copralalia (swearing) uncommon
Tourette’s tx? (3)
Meds
Botox
Deep Brain Stim (DBS)
Dystonia is?
Primary/Generalized?
Primary/Focal? (6)
Abn posture/position
Idiopath torsion (childhood)
Cervical, eyelids, task-specific, oral-mandibular, lingual, laryngeal
Dystonia: 2°?
Neurodegenerative
Geste Antagoniste is?
Physical gesture (e.g. touching one’s chin ) which temporarily interrupts dystonia
Dystonia tx? (6)
DA MM relax BZs Antichol Botox DBS
Fxnl Mvmt Disorders are?
Multiple somatizations (sxs) w/o cause
Fxnl Mvmt Disorders presentation? (4)
Abrupt onset
Bizarre, exaggerated, rhythmic movements
Distraction/inconsistent movements
Spontaneous remission