Exam 4 ALS

Question 1

Amyotropic Lateral Sclerosis is?

Answer 1

Idiopathic dz of UMN and LMN

NO sensation ∆s

Question 2

ALS presentation?

Answer 2

Painless, progressive

BOTH upper and lowerMN signs in same limb
(spastic, hyperreflex, twitching, wasting)
TONGUE fasiculations

Weakness starts in hands/arms then legs

Question 3

ALS diagnostics?

NCS findings?

EMG findings?

Imaging findings?

Answer 3

Clinical

NCS = N

EMG = widespread involv of prox and distal mm

Imag = N

Question 4

ALS prognosis?

Answer 4

Time b/w sxs and death = 27 - 43 months

Question 5

UMN lesion presentation?

Answer 5

Dependent on level of lesion

Spasticity (Initial resistance that gives way)

Hypertonia (Limbs held in position of strongest mm contraction)

Hyper-reflex
Clonus
Babinski
Abdominal stroke reflex absent

Question 6

LMN lesion presentation?

Answer 6

Hyporeflex
Hypotonia
Fasciculation
Wasting