Exam 3 Seizures Flashcards

1
Q

Seizures are?

A

Sudden, excessive electrical discharges in brain

Causes uncontrolled mvmt, disorientation, LOC

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2
Q

Epilepsy is?

A

Recurrent seizures from chronic, underlying syndrome

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3
Q

Seizures caused by? (10)

A

1) Trauma: hypoxia, injury
2) Congenital defects
3) Metabolic: hypogly/Na+, hypo/hyperCa2+, uremia, Reye’s
4) Infection
5) Drugs or w/d
6) Toxins: lead, organophos
7) Neoplasm
8) Vascular: CVA, HTN, arteritis, sickle
9) Degenerative neuro dz
10) Fever in kids

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4
Q

Ictal?

Interictal?

Postictal?

A

During seizure

Between seizures

After seizure

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5
Q

Clonic?

Tonic?

Clonic-Tonic?

A

Repetitive, flex/ext

Rigid, continuous tension

Both

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6
Q

Epileptogenic?

Epileptiform?

A

Factors that ↓ threshold = more seizures

Having appearance of seizure activity

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7
Q

Simple Partial Seizures Presentation?

A

No ∆ in LOC
Can interact
Recalls event

Specific signs depend on focal area of brain

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8
Q

Simple Partial Seizures:

Motor sxs?

Sensory sxs?

Temporal lobe sxs?

Occipital lobe sxs?

A

Motor:
Jackson = Clonic mvmt start in hand/foot -> progress thru limb
Todd’s = Paralysis lasting min to hrs

Sensory: Paresthesia, Numbness

Temporal: Deja vu, Epigastric discomfort

Occ: Flashing lights, visual ∆

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9
Q

Complete Partial Seizures presentation?

A

Combo of focal motor/sensory w/ altered consciousness

Fluctuation in attitude, attention, behavior, memory

Epigastric/Abd sensations

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10
Q

Complete Partial Seizures:

Heralding sign?

Ictal phase?

Postictal phase?

A

P pre-seizure aura

Sudden arrest of behavior/motionless stare,
Automatisms (chewing, smacking, outbursts, runnning)

Confusion, amnesia

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11
Q

Generalized Seizures located where?

A

Bilat from both hemi simultaneously

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12
Q

Absence Seizure is?

Onset?

Duration?

Presentation?

A

Sudden LOC w/o loss of postural control

Childhood

Seconds

Subtle, bilat automatisms
No post confusion

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13
Q

Tonic-Clonic Seizure presentation:

Tonic? (3)

Clonic? (3)

Post? (4)

A

Sudden LOC, falls down

Tonic:
10-40 sec
Rigid, eyes roll back, moan/cry
Cyanosis, ↑ BP/HR/Pupils

Clonic:
30 sec - 3 min
Jerking, frothing
Lose bowel/bladder

Post:
Min - hrs
Confused/sleepy
HA
Amnesia
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14
Q

Status Epilepticus is?

A

EMERGENCY

Continuous or multiples w/o regaining consciousness

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15
Q

Status Epilepticus can lead to?

A

Card/Resp dysf
Metabolic dysf
Hyperthermia
Brain damage if > 2 hrs

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16
Q

Generalized Myoclonic Seizure is?

C seen with? (3)

A

Sudden, brief generalized mm contraction of limbs/trunk

Metabolic dis
Degenerative CNS dz
Anoxic brain injury

17
Q

Atonic Seizure is?

Presentation?

a/w?

A

Sudden loss of postural tone
1-2 sec

Brief LOC impairment
Brief head drop/nod
No post confusion

Other forms of epilepsy

18
Q

Hx should include what questions about the seizure? (6)

A
Actually a seizure?
Local or general?
Consciousness impaired?
Tonic-Clonic mvmts?
Sustain injury?
Loss of bowel/bladder?
19
Q

Physical exam should include checking what for injury? (5)

A
Tongue
Scalp
Neck
Back
Extremities
20
Q

Seizure labs? (6)

A
CBC
UA
CMP
Serum Mg
Tox screen
Syphillis
21
Q

Seizures specialized tests? (5)

A
EEG = KEY DIAG TEST
Cranial CT/MRI and CXR for all new
Lumbar punct
Cx (blood, urine, CSF)
PET/SPECT if refractory
22
Q

Seizure DDX? (6)

A
Syncope
Psych dis
Metabolic dis
TIA
Sleep dis
Mvmt dis
23
Q

Acute treatment of seizures: Immediate?

A

ABC
Turn on side
Protect head

24
Q

Acute treatment of Status Elip? (7)

If not responding?

A
IV loraz/diazepam
IV phosphenytoin/phenytion
IV 50% Glu
IV Narcan
IV Thiamine 100 mg
STAT labs
Cardiac monitoring

IV phenobarb/Midazolam

25
Q

Chronic tx of seizures? (4)

A

Tx cause
Avoid triggers
Antiepileptic
Neuro consult

26
Q

Tx w/ Antiepileptic meds begin how?

Monitoring?

A

Single med, titrate

Follow blood levels

27
Q

Antiepileptic meds for Focal Seizures? (3)

A

Carbamazepine (Tegretol)
Phenytoin (Dilantin)
Valproic Acid (Depakote)

28
Q

Antiepileptic meds for General Tonic-Clonic Seizures? (3)

A

Val acid
Carbam
Phenty

29
Q

Antiepileptic meds for General Absence Seizures? (2)

A

Ethosuximide (Zarontin)

Val acid

30
Q

Antiepileptic meds for General Myoclonic and Atonic Seizures? (1)

A

Val acid

31
Q

Refractory Seizures tx?

A

Temporal lobectomy
Lesionectomy
Corpus callosotomy
Vagal nn stim (pacemaker)