Exam 3 Renal meds Flashcards
Digoxin interactions:
Loops?
β-block?
HypoK+ -> dig toxicity
Dig and β both cause brady -> together = AV block
Loop + β = hypoTN = ↓ renal flow = dig toxicity
Loops + β-blocks interaction?
Both lower BP -> hypoTN
Diuretic that does not cause digoxin toxicity?
spironolactone
Drugs that cause digoxin interactions:
Antiarrhy?
ABX?
Other?
Amiodarone
Nifedipine, verapamil
Quinidine
EMC, TCN
IV Ca2+
Thyroid
Digitalis toxicity tx?
Discontinue drug
Adequate K+
Cardiac monitor
NO cardioversion
Which ABX has to be adjusted for renal dz?
Which don’t?
Levaquin
Ceftriax
Doxy
Metformin and renal dz adjustments:
GFR > 60?
45-60?
30-45?
<30?
GFR > 60, ok to use
45-60, monitor renal fxn Q 3-6mo
30-45, reduce dose by 50%
<30, discontinue