Exam 3 Renal meds Flashcards

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1
Q

Digoxin interactions:

Loops?

β-block?

A

HypoK+ -> dig toxicity

Dig and β both cause brady -> together = AV block

Loop + β = hypoTN = ↓ renal flow = dig toxicity

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2
Q

Loops + β-blocks interaction?

A

Both lower BP -> hypoTN

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3
Q

Diuretic that does not cause digoxin toxicity?

A

spironolactone

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4
Q

Drugs that cause digoxin interactions:

Antiarrhy?

ABX?

Other?

A

Amiodarone
Nifedipine, verapamil
Quinidine

EMC, TCN

IV Ca2+
Thyroid

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5
Q

Digitalis toxicity tx?

A

Discontinue drug
Adequate K+
Cardiac monitor
NO cardioversion

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6
Q

Which ABX has to be adjusted for renal dz?

Which don’t?

A

Levaquin

Ceftriax
Doxy

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7
Q

Metformin and renal dz adjustments:

GFR > 60?

45-60?

30-45?

<30?

A

GFR > 60, ok to use

45-60, monitor renal fxn Q 3-6mo

30-45, reduce dose by 50%

<30, discontinue

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