Antidepressants Flashcards

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1
Q

TCA toxicity causes what? (9)

A
Torsades
Arrhy
Severe hypoTN
Agitation/delirium
Seizures
Very high fever
Coma/shock
Metabolic acidosis
Respiratory depression
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2
Q

TCA toxicity tx? (4)

A

Gastric lavage + activated charcoal
Mg + isoproterenol (for torasdes)
Lido, propranolol, pheny (arrhy, seizure)
Sodium bicarb, KCl (acidosis)

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3
Q

MAO-A metabolizes?

A

NE and 5HT in CNS and GI

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4
Q

MAO-B metabolizes?

A

DA in CNS

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5
Q

Serotonin Syndrome is?

A

Overstim of 5HT receptors

Cognitive sxs: delirium, convulsion, coma

Autonom sxs: HTN, tachy

Somatic sxs: myoclonus, high fever

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