Antidepressants Flashcards
1
Q
TCA toxicity causes what? (9)
A
Torsades Arrhy Severe hypoTN Agitation/delirium Seizures Very high fever Coma/shock Metabolic acidosis Respiratory depression
2
Q
TCA toxicity tx? (4)
A
Gastric lavage + activated charcoal
Mg + isoproterenol (for torasdes)
Lido, propranolol, pheny (arrhy, seizure)
Sodium bicarb, KCl (acidosis)
3
Q
MAO-A metabolizes?
A
NE and 5HT in CNS and GI
4
Q
MAO-B metabolizes?
A
DA in CNS
5
Q
Serotonin Syndrome is?
A
Overstim of 5HT receptors
Cognitive sxs: delirium, convulsion, coma
Autonom sxs: HTN, tachy
Somatic sxs: myoclonus, high fever