Exam 2 Malaria/Protoz

Question 1

Plasmodia Falciparum causes what?

Presentation?

Answer 1

Malignant 3° malaria

Most lethal
Fever Q 3 days
No 2° tissue form

Question 2

P. Vivax causes what?

Presentation?

Answer 2

Benign 3° malaria

Most C
Fever Q 3 days
Yes 2° tissue form

Question 3

P. Malariae causes what?

Presentation?

Answer 3

4° malaria

Rare
Fever Q 4 days
No 2° tissue form

Question 4

Plasmodia lifecycle?

Answer 4

Female injects Sporozoites into host ->

Sporozoites into liver cells ->

Replicate into Merozoites ->

Into RBCs -> Grow into Schizonts ->

RBC burst/Release new Merozoites and toxins

Question 5

Blood Schizonticides act on what?

Result in what?

Do not work on what?

Answer 5

RBC form of parasite

Sxs suppression and “clinical cure”

Tissue forms

Question 6

Tissue Schizonticides act on what?

Results in what?

Do not work on what?

Answer 6

Hepatic forms of parasite

Kills tissue forms, prevent relapse

Can’t tx Sxs if RBC form is already established

Question 7

Gametocidal Agents act on what?

Results in what?

Answer 7

Gametocytes

Spread of dz but not helpful to someone already w/ active dz

Question 8

Clinical Cure is?

Answer 8

RBC form eradicated

Question 9

Radical Cure is?

Answer 9

All forms eradicated

Question 10

Entamoeba Histolytica transmission/lifecycle?

Results in?

Answer 10

Cysts ingested in H2O or spread anal-oral

Active Trophozoites penetrate intest mucosa

Inflamm/Severe bloody D

P spread to liver -> cause hepatitis

Question 11

Giardia Iamblia transmission/lifecycle?

Results in?

Answer 11

Same trans as e. histolytica

Active Trophozoites bind sm intest ->
Block nutrient absorb

Diarr

Question 12

T. Gondii causes what?

Answer 12

Life-threat infection in immunocomp

Congenital toxoplasmosis in fetus

Question 13

P. Jiroveci causes what?

Answer 13

PNA in AIDS (major cause of death)