Exam 3 GI

Question 1

Phenergan Indication/MOA?

Answer 1

Antiemetic

D, M, H block

Question 2

Phenergan C/I?

Answer 2

< 2 yo
Elderly
Severe resp dz
CNS depressants

Question 3

Phenergan S/E?

Answer 3

Sedation

Resp depress

Question 4

Zofran Indication/MOA?

Answer 4

Antiemetic - prevention
5-HT3 block
Safer for preggos

Question 5

Zofran S/E?

Answer 5

Very few

Question 6

Reglan Indication? (4)

Answer 6

Antiemetic/Promotility
N/V prevent
GERD
Gastroparesis
NOT 1st choice (s/e)

Question 7

Reglan S/E?

Answer 7

EPS

TARDIVE DYSKINESIA

Question 8

Imodium Indications/MOA?

Answer 8

Antidiarr

Binds gut opioid recep -> inhib peristalsis, ↑anal sphincter

Question 9

Imodium precautions? (3)

S/E? (3)

Answer 9

Bloody/bacterial diarr
Diarr > 48 hrs
IBD

Toxic mega
Ileus
Constp

Question 10

Lomotil Indication/MOA?

Answer 10

Antidiarr

Inhib peristalsis

Question 11

Lomotil precautions?

S/E? (4)

Answer 11

Same as imodium

Toxic mega
Ileus
Constp
Resp depress

Question 12

Pepto-Bismol MOA? (4)

Answer 12

Absorb H2O
↓secretions
Binds toxins
Antimicrobial

Question 13

Pepto precautions?

S/E? (2)

Answer 13

C/I ASA allergy, kids

Black stool
Black tongue

Question 14

Docusate Na+ Indication/MOA?

Answer 14

Laxative

Mix stool/fat/H2O

Question 15

Docusate Na+ precautions?

Answer 15

Acute abd
Obstruction

Safe for preggos

Question 16

Mineral Oil Indications/MOA?

Answer 16

Laxative

Coats/lubes stool

Question 17

Mineral Oil precautions?

Answer 17

Old

Question 18

Mg citrate Indication?

Precautions? (3)

S/E? (2)

Answer 18

Laxative - ACUTE

Acute abd
Obstruction
Renal dysf

e-
Cramping

Question 19

Miralax Indication?

Precaution?

S/E?

Answer 19

Laxative - chronic

Obstruction

e-

Question 20

Amitiza (lubiprostone) Indication/MOA?

Precaution?

S/E? (3)

Answer 20

Laxative - Chronic, IBS
Activate Cl- chan -> ↑secretions/motility

Obstruction

N/D
HA
Abd pain

Question 21

Antacids indications?

S/E?

Answer 21

Occastional dyspep, mild GERD

Inhib absorb/elim many meds

Question 22

H2 Blockers meds?

Indications?

Precautions?

Answer 22

Zantac, Pepcid

Dyspep, GERD, PUD

↑Warfarin
↓absorb lots of meds

Question 23

PPI meds?

Indications? (4)

Answer 23

-prazoles

Mod/Sev GERD
PUD
Erosive esoph
Ulcer prophy w/ NSAIDs

Works best in a.m.

Question 24

PPI S/E?

Precautions?

Answer 24

N/D
HA

↓Ca2+ absorp
↓efficacy of Plavix
↑risk of infection